Paracetamol como coadyuvante a opioides fuertes en dolor oncológico moderado a intenso: ¿es realmente efectivo?

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dc.catalogadoraba
dc.contributor.authorLeiva, Ofelia
dc.contributor.authorPérez Cruz, Pedro
dc.date.accessioned2025-04-01T15:33:20Z
dc.date.available2025-04-01T15:33:20Z
dc.date.issued2021
dc.description.abstractCancer related pain is one of the most frequent and relevant symptoms in patients with malignant tumors, causing a huge impact in their quality of life. According to the Chilean Public Health System Technical Report of the Cancer Pain Control and Palliative Care Program 2013-2014, 90% of cancer patients admitted to the Program experienced pain, being moderate or intense in 34%. International and local standards recommend the use of strong opioids (morphine, methadone, or fentanyl) associated with adjuvants such as paracetamol as an initial strategy for pain management. This recommendation assumes that the use of combined analgesics could allow the use of lower opioid doses to obtain similar analgesic effect, decreasing the occurrence of opioid side effects. However, this technical report also describes that there is uncertainty about the impact of paracetamol as an adjuvant in patients with cancer pain who are already receiving strong opioids. This review aims to describe the current state of the art regarding the role of paracetamol as a coadjuvant in cancer pain patients.
dc.format.extent7 páginas
dc.fuente.origenORCID
dc.identifier.doi10.4067/S0034-98872021000600899
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedid34751349
dc.identifier.scieloidS0034-98872021000600899
dc.identifier.scopusid2-s2.0-85119593387
dc.identifier.urihttps://doi.org/10.4067/S0034-98872021000600899
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/103079
dc.identifier.wosidWOS:000733624100010
dc.information.autorucEscuela de Medicina; Leiva, Ofelia; 0000-0001-8136-3505; 167303
dc.information.autorucEscuela de Medicina; Pérez Cruz, Pedro; 0000-0001-6265-6919; 4140
dc.issue.numero6
dc.language.isoes
dc.nota.accesocontenido completo
dc.pagina.final905
dc.pagina.inicio899
dc.publisherSociedad Medica de Santiago
dc.revistaRevista Medica de Chile
dc.rightsacceso abierto
dc.rights.licenseAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.en
dc.subjectAcetaminophen
dc.subjectAnalgesics, Opioid
dc.subjectCancer Pain
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleParacetamol como coadyuvante a opioides fuertes en dolor oncológico moderado a intenso: ¿es realmente efectivo?
dc.title.alternativeParacetamol as an adjuvant to opioids for cancer pain management
dc.typeartículo de revisión
dc.volumen149
sipa.codpersvinculados167303
sipa.codpersvinculados4140
sipa.trazabilidadORCID;2025-03-03
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