Carbon-Based Materials in Photodynamic and Photothermal Therapies Applied to Tumor Destruction

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dc.contributor.authorLagos, Karina J.
dc.contributor.authorBuzza, Hilde H.
dc.contributor.authorBagnato, Vanderlei S.
dc.contributor.authorRomero, Maria Paulina
dc.date.accessioned2024-01-10T14:23:37Z
dc.date.available2024-01-10T14:23:37Z
dc.date.issued2022
dc.description.abstractWithin phototherapy, a grand challenge in clinical cancer treatments is to develop a simple, cost-effective, and biocompatible approach to treat this disease using ultra-low doses of light. Carbon-based materials (CBM), such as graphene oxide (GO), reduced GO (r-GO), graphene quantum dots (GQDs), and carbon dots (C-DOTs), are rapidly emerging as a new class of therapeutic materials against cancer. This review summarizes the progress made in recent years regarding the applications of CBM in photodynamic (PDT) and photothermal (PTT) therapies for tumor destruction. The current understanding of the performance of modified CBM, hybrids and composites, is also addressed. This approach seeks to achieve an enhanced antitumor action by improving and modulating the properties of CBM to treat various types of cancer. Metal oxides, organic molecules, biopolymers, therapeutic drugs, among others, have been combined with CBM to treat cancer by PDT, PTT, or synergistic therapies.
dc.description.funderFAPESP (Fundaco de Amparoa Pesquisa do Estado de Sao Paulo)
dc.description.funderEscuela Politecnica Nacional Project
dc.fechaingreso.objetodigital2024-05-02
dc.format.extent28 páginas
dc.fuente.origenWOS
dc.identifier.doi10.3390/ijms23010022
dc.identifier.eissn1422-0067
dc.identifier.pubmedidMEDLINE:35008458
dc.identifier.urihttps://doi.org/10.3390/ijms23010022
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80119
dc.identifier.wosidWOS:000751051300001
dc.information.autorucFacultad de Física; Harb Buzza, Hilde; S/I; 1232017
dc.issue.numero1
dc.language.isoen
dc.nota.accesocontenido completo
dc.publisherMDPI
dc.revistaInternational Journal of Molecular Sciences
dc.rightsacceso abierto
dc.subjectphototherapy
dc.subjectcancer
dc.subjectgraphene oxide
dc.subjectreduced graphene oxide
dc.subjectgraphene quantum dots
dc.subjectcarbon dots
dc.subjectGRAPHENE QUANTUM DOTS
dc.subjectNANO-GRAPHENE
dc.subjectDRUG-DELIVERY
dc.subjectIN-VITRO
dc.subjectOXIDE
dc.subjectNANOTUBES
dc.subjectFACILE
dc.subjectPHOTOSENSITIZER
dc.subjectNANOPARTICLES
dc.subjectNANOMATERIALS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCarbon-Based Materials in Photodynamic and Photothermal Therapies Applied to Tumor Destruction
dc.typeartículo de revisión
dc.volumen23
sipa.codpersvinculados1232017
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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