Acute Liver Injury Among Pediatric Liver Transplantation Recipients With Coronavirus Disease 2019: An International Collaborative Study

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dc.contributor.authorSin, Priscila
dc.contributor.authorDiaz, Luis Antonio
dc.contributor.authorMartinez, Mercedes
dc.contributor.authorVizcaya, Cecilia
dc.contributor.authorD'Agostino, Daniel
dc.contributor.authorGana, Juan Cristobal
dc.date.accessioned2025-01-20T22:09:56Z
dc.date.available2025-01-20T22:09:56Z
dc.date.issued2021
dc.description.abstractCoronavirus disease 2019 (COVID-19) is an ongoing pandemic. The occurrence of acute liver injury (ALI) has been reported in liver transplant (LT) recipients; however, the findings on children remain controversial. This is the first extensive, worldwide report on the impact of COVID-19 on pediatric LT recipients. Our online survey reported 110 pediatric LT recipients with severe acute respiratory syndrome coronavirus 2 infection. Of these, 37 were symptomatic and 20 out of them (54%) had complicated COVID-19, which included ALI and acute liver graft rejection. No mortality was reported. Pediatric LT recipients who had undergone transplantation less than 6 months before contracting COVID-19 had a greater number of hospital admissions and a higher ALI frequency (P = 0.013 and P = 0.033, respectively) than those who had undergone transplantation more than 6 months prior. Our study found that COVID-19 cases among pediatric LT recipients demonstrated a high complication rate. We propose that these patients must be followed up strictly.
dc.fuente.origenWOS
dc.identifier.doi10.1097/MPG.0000000000003213
dc.identifier.eissn1536-4801
dc.identifier.issn0277-2116
dc.identifier.urihttps://doi.org/10.1097/MPG.0000000000003213
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94354
dc.identifier.wosidWOS:000683060000026
dc.issue.numero3
dc.language.isoen
dc.pagina.final394
dc.pagina.inicio391
dc.revistaJournal of pediatric gastroenterology and nutrition
dc.rightsacceso restringido
dc.subjectCoronavirus disease 2019
dc.subjectimmunosuppression
dc.subjectpediatric liver transplantation
dc.subjectsevere acute respiratory syndrome coronavirus 2
dc.subjectviral hepatitis
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAcute Liver Injury Among Pediatric Liver Transplantation Recipients With Coronavirus Disease 2019: An International Collaborative Study
dc.typeartículo
dc.volumen73
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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