Adverse pregnancy and perinatal outcomes in Latin America and the Caribbean: systematic review and meta-analysis

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dc.catalogadorjlo
dc.contributor.authorBlanco, Estela
dc.contributor.authorMarin, Marcela
dc.contributor.authorNunez, Loreto
dc.contributor.authorRetamal, Erika
dc.contributor.authorOssa, Ximena
dc.contributor.authorWoolley, Katherine E.
dc.contributor.authorOludotun, Tosin
dc.contributor.authorBartington, Suzanne E.
dc.contributor.authorMaria Delgado-Saborit, Juana
dc.contributor.authorHarrison, Roy M.
dc.contributor.authorRuiz-Rudolph, Pablo
dc.contributor.authorElisa Quinteros, María
dc.date.accessioned2025-12-10T18:55:46Z
dc.date.available2025-12-10T18:55:46Z
dc.date.issued2022
dc.description.abstractObjective. To estimate the point prevalence and likely ranges of pregnancy-induced hypertension, pre-eclampsia, gestational diabetes, low birth weight and preterm delivery in Latin America and the Caribbean, and evaluate the heterogeneity of the estimates. Methods. We conducted a systematic review and meta-analysis of observational studies reporting the prev-alence of maternal and perinatal adverse outcomes in populations in Latin American and the Caribbean published between 2000 and 2019 in English, Spanish, or Portuguese. We searched PubMed, Embase, and LILACS. We estimated the point prevalence and evaluated overall heterogeneity and, in sub-group analyses, heterogeneity by study design and level of bias. Results. Of 1087 records retrieved, 50 articles were included in the review: two on hypertensive disorders of pregnancy, 14 on pre-eclampsia, six on gestational diabetes, nine on low birth weight and 19 on preterm birth. No meta-analysis for hypertensive disorders of pregnancy could be done because of the small number of studies. Point prevalence estimates and 95% confidence intervals (CIs) for pre-eclampsia, gestational diabe-tes, low birth weight, and preterm birth were: 6.6% (95% CI: 4.9%, 8.6%), 8.5% (95% CI: 3.9%, 14.7%), 8.5% (95% CI: 7.2%, 9.8%), and 10.0% (95% CI: 8.0%, 12.0%), respectively. We observed substantial heterogeneity overall and by study design. No major differences in estimates were observed by level of bias. Conclusions. The results of this study provide updated estimates of some of the most prevalent adverse preg-nancy and perinatal outcomes in Latin America and the Caribbean. They highlight that important heterogeneity exists in prevalence estimates, which may reflect the diversity of populations in the region.
dc.fechaingreso.objetodigital2025-12-10
dc.format.extent10 páginas
dc.fuente.origenWOS
dc.identifier.doi10.26633/RPSP.2022.21
dc.identifier.issn1020-4989
dc.identifier.scopusidSCOPUS_ID:85130425968
dc.identifier.urihttps://doi.org/10.26633/RPSP.2022.21
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/107344
dc.identifier.wosidWOS:000795771500001
dc.information.autorucEscuela de Medicina; Blanco, Estela; S/I; 1232774
dc.language.isoen
dc.nota.accesocontenido completo
dc.revistaRevista Panamericana de Salud Pública
dc.rightsacceso abierto
dc.subjectHypertension
dc.subjectPregnancy-induced
dc.subjectPre-eclampsia
dc.subjectDiabetes
dc.subjectGestational
dc.subjectInfant
dc.subjectLow birth weight
dc.subjectPremature birth
dc.subjectLatin America
dc.subjectCaribbean Region
dc.subject.ddc610
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAdverse pregnancy and perinatal outcomes in Latin America and the Caribbean: systematic review and meta-analysis
dc.typereseña
dc.volumen46
sipa.codpersvinculados1232774
sipa.codpersvinculados1232774
sipa.codpersvinculados134957
sipa.trazabilidadWOS;2022-07-08
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