Browsing by Author "Villagrán Torres, Andrea Alejandra"

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    Functional gastrointestinal disorders in children from low socio-economic status and Helicobacter pylori infection
    (2018) Jaime Méndez, María Francisca; Villagrán Torres, Andrea Alejandra; Hernández Rocha, Cristián Antonio; Ortiz Aparicio, Freddy Miguel; Serrano Honeyman, Carolina; Harris Diez, Paul Richard
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    Helicobacter pylori-associated hypochlorhydria in children, and development of iron deficiency
    (2013) Harris D., Paul R.; Serrano Honeyman, Carolina; Villagrán Torres, Andrea Alejandra; Walker, Marjorie M.; Thomson, Melanie; Duarte, Ignacio; Windle, Henry J.; Crabtree, Jean E.
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    Interleukin-1 beta and Tumor Necrosis Factor-alpha Polymorphisms as Iron Deficiency Risk Markers in Helicobacter pylori-Infected Children
    (2012) Serrano Honeyman, Carolina Andrea; Villagrán Torres, Andrea Alejandra; Venegas, Alejandro; Toledo, Hector; Crabtree, Jean E.; Harris Diez, Paul Richard
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    Letter: childhood recurrent abdominal pain is associated with increased duodenal eosinophilia independent of Helicobacter pylori infection
    (WILEY, 2023) Wauters, Lucas; Harris Diez, Paul Richard; Walker, Marjorie M.; Serrano Honeyman, Carolina Andrea; Villagrán Torres, Andrea Alejandra; Rakhra, Gurpreet S.; Crabtree, Jean E.; Talley, Nicholas J.
    LINKED CONTENT This article is linked to Broeders et al paper. To view this article, visit
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    Some key factors in medical writing
    (2009) Villagrán Torres, Andrea Alejandra; Harris Diez, Paul Richard
    The purpose of scientific research is to disseminate their results in a publication. Scientists, clinicians, graduate and postgraduate students are judged and are primarily known for their publications. A scientific experiment whilst their results may be outstanding does not end until those results are published. Thus, the scientists not only have to "do" science but also "write" science. A poor wording could prevent or delay the publication of an excellent scientific work. The purpose of this article is to help scientists and students to prepare manuscripts that are likely to be accepted for publication and to be perfectly understood when issued. As the requirements journal vary widely among disciplines, and even within a single discipline, it is not possible to make recommendations that are universally acceptable. Therefore, this article will get its importance, insofar as it is taken as a guide for those professionals who wish to publish their studies in national and international journals.
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    Valores de normalidad de eosinófilos en mucosa gástrica y duodenal de niños referidos a endoscopía digestiva alta.
    (Sociedad Chilena de Pediatría, 2021) Ortiz Menares, Marlene Andrea; Jaime. Francisca; Ortiz, Loreto; Carrasco Gaete, Ruby; Orellana Gonzalez, Maria José; Torres, Javiera; Villagrán Torres, Andrea Alejandra; Harris D., Paul R.
    With the increasing incidence of food allergies, the presence of eosinophils (Eos) in the gastrointestinal mucosa has received increased attention, particularly in the esophagus and colon. However, normal values for the Eos count in the stomach and duodenum in pediatric patients are still limited. The objective of this study was to estimate Eos reference values in stomach and duodenal biopsies of children referred to upper gastrointestinal endoscopy. Patients and Methods: Cross-sectional study of biopsies from symptomatic children referred to upper gastrointestinal endoscopy. The endoscopic report, Rapid Urease Test for the presence of H. pylori, and the quantitative histological evaluation (number of cells/HFP, high power field) were analyzed. The Eos distribution is described as mean and standard deviation, and also as percentiles since the counts did not have a normal distribution. Statistical analysis included χ2 test, Wilcoxon test, analysis of variance, and linear regression curves were evaluated as appropriate. Results: Of the 170 patients referred to endoscopy, 72 met “normal” criteria (normal endoscopy in macroscopic analysis, negative Rapid Urease Test, and normal biop-sy). The median age was 11 years (range 4-16), and 68% were girls. The Eos count (mean ± 1SD) in gastric antrum (n = 72) was 1.13 ± 1.79 Eos/HPF; in gastric body (n = 27), 1.06 ± 1.79 Eos/HPF; and in duodenum (n = 30), 10.44 ± 7.09 Eos/HPF. There were no significant differences by age and sex, or by H. pylori infection (p = 0.095). Conclusions: We propose an Eos count of 0-3 Eos/HPF for the gastric body, 0-3 Eos/HPF in the antrum, and 3-17 Eos/HPF in the duodenum as a normal range for gastric mucosa in children. This study suggests that in areas with a high prevalence of H. pylori infec-tion, the count of Eos does not seem to be a distinctive element and that Eos are commonly present in the gastroduodenal mucosa.