Browsing by Author "Zapata, Rodrigo"

Now showing 1 - 6 of 6
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    A changing etiologic scenario in liver transplantation for hepatocellular carcinoma in a multicenter cohort study from Latin America
    (2018) Piñero, Federico; Costa, Paulo; Boteon, Yuri Longatto; Hoyos Duque, Sergio; Marciano, Sebastian; Anders, Margarita; Varon, Adriana; Zerega, Alina; Poniachik, Jaime; Soza, Alejandro; Padilla Machaca, Martin; Menendez, Josemaria; Zapata, Rodrigo; Vilatoba, Mario; Munoz, Linda; Maraschio, Martin; Podesta, Luis G.; McCormack, Lucas; Gadano, Adrian; Fatima Boin, Ilka S. F.; Garcia, Parente; Silva, Marcelo
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    An update on the management of hepatitis C : guidelines for protease inhibitor-based triple therapy from the Latin American Association for the Study of the Liver
    (2013) Chávez Tapia, Norberto C.; Ridruejo, Ezequiel; Alves De Mattos, Angelo; Bessone, Fernando; Druich, Jorge; Sánchez Avila, Juan F.; Cheinquer, Hugo; Zapata, Rodrigo; Uribe, Misael; Soza, Alejandro; Bosques Padilla, Francisco; Gadano Espinoza, Adrián; Dávalos Moscol, Milagro; Marroni, Claudio; Muñoz Espinoza, Linda; Castro Narro, Graciela; Paraná, Raimundo; Méndez Sánchez, Nahum
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    Latin American Association for the Study of the Liver (ALEH) guidance of preoperative care in liver transplantation: referral criteria, patient assessment, and waiting list management
    (2025) Mainardi, Victoria; Pages, Josefina; Menéndez, Josemaría; Zapata, Rodrigo; Díaz Piga, Luis Antonio; Marciano, Sebastián; Cairo, Fernando; Padilla-Machaca, Martin; Tenorio, Laura; Urzúa, Álvaro; Navarro, Lucía; Domínguez, Nicolás; Coste, Pablo; Mendizábal, Manuel; Martínez, Jorge; López, Sergio; Varón, Adriana; Alfeu de Medeiros Fleck, jr; Abad Gonzáles, Jhon; Restrepo, Juan Carlos; Codes, Liana; Lisboa Bittencourt, Paulo; Pérez Figueroa, Norma Marlene; Castro-Narro, Graciela; Terrabuio, Débora Raquel B.; Pessoa, Mário Guimarães; Girala, Marcos; Schiavon, Leonardo Lucca; Aguilera, Edgard; Valenzuela Aguilera, Kenia; Samada, Marcia; Gerona, Solange; Villamil, Alejandra
    Liver transplantation (LT) is the standard of care therapy for patients with decompensated cirrhosis, early-stage hepatocellular carcinoma, acute liver failure, and other expanding indications. Latin America is a highly heterogeneous region characterized by an uneven distribution of socio-economic conditions and irregular access to health resources, and consequently LT activity varies across it. This current guidance of preoperative care in LT represents a collaborative effort to assess and standardize preoperative evaluation of liver transplant candidates in Latin America. It is the first position paper of the special interest group on LT of the Latin American Association for the Study of the Liver (ALEH), which draws evidence-based comprehensive recommendations regarding who to refer, the LT assessment and how to manage the patient on the waiting list, taking into consideration their applicability in Latin America.
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    Liver transplantation for hepatocellular carcinoma: impact of expansion criteria in a multicenter cohort study from a high waitlist mortality region
    (2021) Pinero, Federico; Anders, Margarita; Boin, Ilka F.; Chagas, Aline; Quinonez, Emilio; Marciano, Sebastian; Vilatoba, Mario; Santos, Luisa; Hoyos Duque, Sergio; Lima, Agnaldo Soares; Menendez, Josemaria; Padilla, Martin; Poniachik, Jaime; Zapata, Rodrigo; Soza, Alejandro; Maraschio, Martin; Chong Menendez, Ricardo; Munoz, Linda; Arufe, Diego; Figueroa, Rodrigo; de Ataide, Elaine Cristina; Maccali, Claudia; Vergara Sandoval, Rodrigo; Bermudez, Carla; Podesta, Luis G.; McCormack, Lucas; Varon, Adriana; Gadano, Adrian; Mattera, Juan; Villamil, Federico; Rubinstein, Fernando; Carrilho, Flair; Silva, Marcelo
    This study aimed to compare liver transplantation (LT) outcomes and evaluate the potential rise in numbers of LT candidates with hepatocellular carcinoma (HCC) of different allocation policies in a high waitlist mortality region. Three policies were applied in two Latin American cohorts (1085 HCC transplanted patients and 917 listed patients for HCC): (i) Milan criteria with expansion according to UCSF downstaging (UCSF-DS), (ii) the AFP score, and (iii) restrictive policy or Double Eligibility Criteria (DEC; within Milan + AFP score <= 2). Increase in HCC patient numbers was evaluated in an Argentinian prospective validation set (INCUCAI; NCT03775863). Expansion criteria in policy A showed that UCSF-DS [28.4% (CI 12.8-56.2)] or "all-comers" [32.9% (CI 11.9-71.3)] had higher 5-year recurrence rates compared to Milan, with 10.9% increase in HCC patients for LT. The policy B showed lower recurrence rates for AFP scores <= 2 points, even expanding beyond Milan criteria, with a 3.3% increase. Patients within DEC had lower 5-year recurrence rates compared with those beyond DEC [13.3% (CI 10.1-17.3) vs 24.2% (CI 17.4-33.1; P = 0.0006], without significant HCC expansion. In conclusion, although the application of a stricter policy may optimize the selection process, this restrictive policy may lead to ethical concerns in organ allocation (NCT03775863).
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    Management of nonalcoholic fatty liver disease : an evidence-based clinical practice review
    (2014) Arab Verdugo, Juan Pablo; Candia Balboa, Roberto; Zapata, Rodrigo; Muñoz, Cristián; Arancibia, Juan P.; Poniachik, Jaime; Soza, Alejandro; Fuster, Francisco; Brahm, Javier; Sanhueza, Edgar; Contreras, Jorge; Cuellar, M. Carolina; Arrese Jiménez, Marco; Riquelme Pérez, Arnoldo
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    Results of liver transplantation for hepatocellular carcinoma in a multicenter latin American cohort study
    (2018) Pinero, Federico; Costa, Paulo; Boteon, Yuri L.; Hoyos Duque, Sergio; Marciano, Sebastian; Anders, Margarita; Varón, Adriana; Zerega, Alina; Poniachik, Jaime; Soza, Alejandro; Padilla Machaca, Martín; Menéndez, Josemaría; Zapata, Rodrigo; Vilatoba, Mario; Muñoz, Linda; Maraschio, Martín; Fauda, Martín; McCormack, Lucas; Gadano, Adrian; Boin, Ilka SF; Parente García, Jose H.; Silva, Marcelo