Browsing by Author "Wehrmeister, Fernando C."

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    Inequalities on medical diagnosis and underdiagnosis of COPD: The PLATINO study
    (EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2015) Wehrmeister, Fernando C.; Menezes, Ana Maria B.; Montes de Oca, Maria; Talamo, Carlos; Victorina Lopez Varela, Maria; Muino, Adriana; Valdivia, Gonzalo; Lisboa, Carmem; Jardim, Jose R.; Perez Padilla, Rogelio
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    Outcomes for symptomatic non-obstructed individuals and individuals with mild (GOLD stage I) COPD in a population based cohort
    (2018) Perez-Padilla, Rogelio; Wehrmeister, Fernando C.; Montes de Oca, María; Lopez, Maria Victorina; Jardim, Jose R.; Muiño A.; Valdivia Cabrera, Gonzalo; Menezes A.M.B.
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    The PLATINO study: description of the distribution, stability, and mortality according to the Global Initiative for Chronic Obstructive Lung Disease classification from 2007 to 2017
    (2017) Menezes, Ana M.; Wehrmeister, Fernando C.; Pérez Padilla, Rogelio; Viana, Karynna P.; Soares, Claudia; Müllerova, Hana; Valdivia Cabrera, Gonzalo; Jardim, José R.; Montes de Oca, María
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    Trajectories of Spirometric Patterns, Obstructive and PRISm, in a Population-Based Cohort in Latin America
    (2023) Perez-Padilla, Rogelio; de Oca, Maria Montes; Thirion-Romero, Ireri; Wehrmeister, Fernando C.; Lopez, Maria Victorina; Valdivia, Gonzalo; Jardim, Jose R.; Muino, Adriana; Menezes, Ana Maria B.; Perez-Padilla, Rogelio
    Background: Preserved ratio impaired spirometry (PRISm) has been associated with adverse outcomes and increased transition to other spirometric categories over time. We aimed to examine its prevalence, trajectories over time, and outcomes in a population-basedMethods: Data were obtained from two population-based surveys of adults from three cities in Latin America (PLATINO study), conducted on the same individuals 5-9 years after their baseline examination. We estimated the frequency of PRISm defined by FEV1 /FVC & GE;0.70 with FEV1 <80%, describing their clinical characteristics, longitudinal transition trajectories over time, factors associated with the transition.Results: At baseline, 2942 participants completed post-bronchodilator spirometry, and 2026 at both evaluations. The prevalence of normal spirometry was 78%, GOLD-stage 1 10.6%, GOLD 2-4 6.5%, and PRISm was: 5.0% (95% CI 4.2-5.8). PRISm was associated with less schooling, more reports of physician-diagnosis of COPD, wheezing, dyspnea, missing days at work, having & GE;2 exacerbations in the previous year but without accelerated lung function decline. Mortality risk was significantly higher in PRISm (HR 1.97, 95% CI 1.2-3.3) and COPD GOLD 1-4 categories (HR 1.79, 95% CI 1.3-2.4) compared with normal spirometry. PRISm at baseline most frequently transitioned to another category at follow-up (46.5%); 26.7% to normal spirometry and 19.8% to COPD. The best predictors of transition to COPD were closeness of FEV1/FVC to 0.70, older age, current smoking, and a longer FET in the second assessment.Conclusion: PRISm, is a heterogeneous and unstable condition prone to adverse outcomes that require adequate follow-up.
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    Waist circumference and lung function parameters: The PLATINO study
    (EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2012) Menezes, Ana Maria B.; Wehrmeister, Fernando C.; Perez Padilla, Rogelio; Lopez, Maria V.; Muino, Adriana; Talamo, Carlos; Montes de Oca, Maria; Jardim, Jose R.; Valdivia, Gonzalo