Browsing by Author "Wang, Dan"

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    Anchoring black phosphorus quantum dots over carboxylated multiwalled carbon nanotubes: A stable 0D/1D nanohybrid with high sensing performance to Ochratoxin a
    (2022) Huang, Zhiwen; Ceron, Maria Luisa; Feng, Kehuai; Wang, Dan; Camarada, Maria Belan; Liao, Xiaoning
    Exploration of an efficient ochratoxin A (OTA) screening technique is highly important because of its highly toxic effect on human health. Electrochemical sensor, characterized with high accuracy and precise, is an emerging detection technique for toxic agents in food samples. However, the inherent fouling effect and low electro-chemical activity from OTA molecular hinder its practical application in OTA detection. Herein, we prepared a novel 0D/1D nanohybrid by anchoring black phosphorus quantum dots (BPQDs) over carboxylated multiwalled carbon nanotubes (CNTs-COOH) via a facile sonication assisted assembly approach. Characterization techniques together with theoretical approximations reveal that BPQDs can anchor onto the CNTs-COOH via strong covalent reaction, endowing the nanohybrid with high conductivity, high stability and high anti-fouling property. The electrochemical sensor constructed with the 0D/1D nanohybrid shows high electrochemical activity and a good antifouling effect in OTA detection. In optimized conditions, the sensor provide a quantitative determination of OTA in a wide concentration range from 0.4 to 10 mu M with a detection limit of 0.03 mu M. Moreover, the sensor shows high reproductivity and satisfactory anti-interference ability. Satisfactory recoveries that can comparable to those of high-performance liquid chromatography indicate that the sensor is promising for the trace-level analysis of OTA in agricultural crops.
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    Maternal and Fetal Factors Associated With Mortality and Morbidity in a Multi-Racial/Ethnic Registry of Anti-SSA/Ro-Associated Cardiac Neonatal Lupus
    (LIPPINCOTT WILLIAMS & WILKINS, 2011) Izmirly, Peter M.; Saxena, Amit; Kim, Mimi Y.; Wang, Dan; Sahl, Sara K.; Llanos, Carolina; Friedman, Deborah; Buyon, Jill P.
    Background-Cardiac manifestations of neonatal lupus include conduction disease and, rarely, an isolated cardiomyopathy. This study was initiated to determine the mortality and morbidity of cardiac neonatal lupus and associated risk factors in a multi-racial/ethnic US-based registry to provide insights into the pathogenesis of antibody-mediated injury and data for counseling.
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    MoS2 quantum dots and titanium carbide co-modified carbon nanotube heterostructure as electrode for highly sensitive detection of zearalenone
    (2022) Huang, Hao; Camarada, Maria Belen; Wang, Dan; Liao, Xiaoning; Xiong, Wanming; Du, Juan; Xiong, Jianhua; Hong, Yanping
    A novel electrochemical sensor has been fabricated for sensitive determination of zearalenone (ZEA) in food samples based on molybdenum disulfide quantum dots (MoS2 QDs) and two-dimensional titanium carbide (2D-Ti3C2Tx MXene) co-modified multi-walled carbon nanotube (MWCNT) heterostructure. Physical and electrochemical characterizations reveal that 2D-Ti3C2Tx and MoS2 QDs co-modified MWCNTs yields synergistic signal amplification effect, together with large specific surface area and excellent conductivity for the heterostructure, endowing the developed sensor with high detection performance to ZEA. Under optimized conditions, the sensor shows a wide linear range from 3.00 to 300 ng mL(-1) and a low limit of detection (LOD) of 0.32 ng mL(,)(-1) which is far lower than the maximum residue limits (MRLs) settled by the European Commission. In addition, it exhibits excellent selectivity, high reproducibility with a relative standard deviation (RSD) of 1.1%, and good repeatability (RSD 1.1%). In real sample analysis recoveries ranged from 94.8 to 105% showing the proposed electrochemical sensor has high potential in practical applications. This work presents an effective and valuable pathway for the use of novel heterostructure in the biosensing field.