Browsing by Author "Volk, BA"

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    Exploring the genetic role of the HLA-DPB1 locus in Chileans with intrahepatic cholestasis of pregnancy
    (1996) Mella, JG; Roschmann, E; Glasinovic, JC; Alvarado, A; Scrivanti, M; Volk, BA
    Background/Aims: Intrahepatic cholestasis of pregnancy is a rare disease of unknown etiology, with a strikingly higher prevalence in Chile than in most other countries, Although several studies suggest that a genetic predisposition is involved in the pathogenesis, no genetic disease-marker has so far been identified, Using a recently developed HLA-genotyping technique, we performed an association study with a highly polymorphic HLA class II gene in patients with recurrent intrahepatic cholestasis of pregnancy and normal control patients.