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  1. Home
  2. Browse by Author

Browsing by Author "Villarroel del Pino, Luis A."

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    A randomized controlled trial of a brief intervention for alcohol and drugs linked to the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in primary health care in Chile
    (2017) Poblete A., Fernando; Barticevic Lantadilla, Nicolás A.; Zuzulich, Soledad Maria; Portilla, Rodrigo; Castillo Carniglia, Alvaro; Sapag Muñoz de la Peña, Jaime; Villarroel del Pino, Luis A.
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    A risk prediction model for severe intraventricular hemorrhage in very low birth weight infants and the effect of prophylactic indomethacin
    (2014) Luque, M.; Tapia Illanes, José Luis; Villarroel del Pino, Luis A.; Marshall Rivera, Guillermo; Musante, G.; Carlo, W.; Kattan Said, Alberto Javier
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    Academic performance of medical students. A predictable result?
    (SOC MEDICA SANTIAGO, 2000) Bastías, Gabriel; Villarroel del Pino, Luis A.; Zúñiga Parada, Denisse Alejandra; Marshall Rivera, Guillermo; Velasco Fuentes, Nicolas; Mena Concha, Beltrán
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    Adaptación y validación de la escala de bienestar materno en situación de parto : segunda versión para escenarios de asistencia integral
    (2014) Uribe Torres, Claudia; Contreras Mejías, Aixa; Villarroel del Pino, Luis A.
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    Adaptación y validación del instrumento genérico collaboRATE™ para medir la participación de mujeres en la toma de decisiones en salud durante el proceso reproductivo
    (2018) Bravo Valenzuela, Paulina Fabiola; Contreras, Aixa; Dois C., Angelina M.; Villarroel del Pino, Luis A.
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    Una alimentación poco saludable se asocia a mayor prevalencia de síndrome metabólico en la población adulta chilena : estudio de corte transversal en la Encuesta Nacional de Salud 2009-2010
    (2015) Dussaillant, Catalina; Echeverria, Guadalupe; Villarroel del Pino, Luis A.; Marín Larraín, Pedro Paulo; Rigotti Rivera, Attilio
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    Análisis de la ingesta según variables sociodemográficas e identificación de las principales fuentes alimentarias de folatos naturales y sintético en Chile a partir del estudio latinoamericano de nutrición y salud (ELANS)
    (2022) Cárdenas Muñoz, Fernanda; Busso, Dolores; Villarroel del Pino, Luis A.; Pontificia Universidad Católica de Chile. Facultad de Medicina
    Introducción: El ácido fólico (AF) es la forma sintética de la vitamina B9, mientras que el folato natural se encuentra en alimentos. En embarazadas, este micronutriente cumple un rol fundamental previniendo los defectos del tubo neural por lo que la recomendación de ingesta (RDA) en mujeres de edad fértil es 400 µg/día. Para lograrla, se fortifican los alimentos o se administran suplementos de ácido fólico. En Chile, se fortifica obligatoriamente la harina panificable con 1,8 µg AF/kg. Objetivo: Evaluar en sujetos chilenos de zonas urbanas la ingesta de AF y folato natural, y describir sus principales fuentes alimentarias. Métodos: Usando datos de la encuesta ELANS, en la que aplicaron dos encuestas R24Hrs a 879 sujetos de 15-65 años de distintas zonas urbanas de Chile, se extrajo información de nutrientes usando el programa NDS-R. Los análisis estadísticos se realizaron a través de Student t-test, ANOVA/post-test de Bonferroni o Chi-cuadrado, según el número y tipo de variables a comparar, usando SAS® y SPSS®. Los alimentos fueron clasificaron en 19 grupos, analizándose el % de aporte de folato o AF de cada grupo. Se consideraron diferencias estadísticamente significativas a un valor igual a p<0,05. Resultados: La ingesta promedio de folato total a nivel poblacional fue de 589±301 EFD µg/día, siendo el aporte de AF de un 67% del total. El consumo de folato natural y AF fue superior en hombres y en la región de Biobío. En el NSE bajo se observó mayor ingesta de AF. A nivel poblacional, el cumplimiento de la ingesta (% vs el EAR) fue del 84,2% y el nivel mayor al UL de AF fue de 0,5%. La principal fuente de AF fue el pan (64%) y la de folatos las legumbres y frutos secos (21%). Conclusión: La mayoría de los chilenos consumen niveles adecuados de folatos provistos principalmente por el AF en el pan, y además por los folatos en legumbres y frutos secos.
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    Antenatal exposure to magnesium sulfate and neonatal outcomes in very low birth weight infants: a multicenter study
    (2024) Vaz Ferreira, Catalina; Caro, Jose; Villarroel del Pino, Luis A.; Muñoz, Sergio; Álvarez, Patricia; Flores, Gerardo; Herrera, Tamara; Toso, Alberto; Toso Milos, Paulina Alejandra; Tapia Illanes, José Luis; NEOCOSUR Neonatal Network
    Objective: To explore the association between antenatal magnesium sulfate (MgSO4), mortality and incidence of intraventricular hemorrhage (IVH) in very low birth weight (VLBW) infants. Study design: Retrospective, cohort study of infants <32 weeks’ GA born at centers of NEOCOSUR Network between January 2015 and December 2020. Subjects were categorized as exposed vs non-exposed to antenatal MgSO4. Primary outcomes were death, incidence of severe IVH (Grade III-IV) and severe IVH/death. Secondary outcomes included relevant morbidities. Results: 7418 VLBW infants were eligible. Antenatal MgSO4 was associated with a significantly decreased death rate after admission (aOR 0.67 [95% CI, 0.49–0.94]) and severe IVH/ death (aOR 0.68 [95% CI, 0.50–0.93]). No significant reduction in severe IVH was observed (aOR 1.11 [95% CI, 0.72–1.71]). No differences between groups were observed in rates of morbidities. Conclusion: Antenatal MgSO4 was associated with a decreased death rate after admission and in severe IVH/ death.
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    ASSOCIATION BETWEEN PERINATAL FACTORS AND COMPONENTS OF THE METABOLIC SYNDROME AND INSULIN RESISTANCE IN CHILDREN OF PUENTE ALTO, SANTIAGO, CHILE
    (2013) Mardones, Francisco; Pacheco, M.; Dominguez, Angélica; Villarroel del Pino, Luis A.; Eriksson, J. G.; Arnáiz Gómez, Pilar; Barja Y., Salesa; Castillo Valenzuela, Oscar; Farías Jofré, Marcelo
    Background and objectives: we have previously studied the association of prenatal growth with metabolic syndrome (MS) components, including insulin resistance (IR), in about two thousand Chilean low-income urban school-age children (J Devel Orig Health Dis. 2012; 3(4): 237-244). We aim to ascertain with a higher sample size the influence of the above mentioned variables. Methods: retrospective cohort study linking information on MS and IR in school-age, with perinatal records. 3325 children were enrolled in schools in the district of Puente Alto (Santiago, Chile) during 2009-2011. Anthropometry and blood pressure (BP) were assessed. A blood sample for determination of glycemia, insulinemia (quimioluminiscence) and blood lipids was taken; HOMA was calculated and a national standard was applied to select HOMA-IR cases. Cook et al standard was used to define MS. We used Pearson correlation, chi-square test and logistic regression step-by-step. Linear and quadratic associations were tested with Poisson regression. Results: 3290 children had complete information at birth (98.9%) 52.01% women; aged 11.4 + 1 years. The prevalence of MS and IR was 7.26% and 25.47%, respectively. Logistic regression analysis showed an inverse association between birth length (BL), gestational age and birth weight (BW) with most dependent variables studied. However BW showed a direct association with the majority of the dependent variables studied. The waist circumference > 90th percentile, BP > 90th percentile and triglycerides > 110 mg/dl were associated with U-shaped BW, BL and ponderal index, respectively. Conclusions: In this new study we could demonstrate a higher number of U-shaped associations with perinatal variables. New studies with higher sample sizes would permit to show this kind of associations and improve our understanding of the early origins of metabolic diseases.
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    Association of perinatal factors and school performance in primary school Chilean children
    (2013) Villarroel del Pino, Luis A.; Karzulovic Busch, Lorena Karina; Manzi Astudillo, Jorge; Eriksson, Johan; Mardones S., Francisco
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    ASSOCIATION OF SUBCLINICAL ATHEROSCLEROSIS WITH DIFFERENT STANDARDS OF THE METABOLIC SYNDROME AND INSULIN RESISTANCE
    (2013) Arnai, P.; Dominguez, Angélica; Barja Y., Salesa; Godoy, I.; Villarroel del Pino, Luis A.; Castillo Valenzuela, Oscar; Farías Jofré, Marcelo; Mardones, Francisco
    Background and objectives: we have previously selected two metabolic syndrome (MS) components blood pressure (BP) and high density lipoprotein cholesterol (HDLC) as associated with carotid intima media thickness (CIMT) a surrogate marker of subclinical atherosclerosis in children (Rev Med Chile 2012; 140: 1268-75). We aimed to ascertain with a higher sample size the influence of the above mentioned variables and three standards defining the MS plus three standards defining insulin resistance (IR). Methods: A cross-sectional study of 447 children 10-14 years old of low socio-economic strata from an urban area of Chile was performed during years 2009-2011. This sample was selected considering the presence of one or more MS component and IR. Anthropometry and BP were assessed. A blood sample for determination of glycaemia, insulinemia (quimioluminiscence) and blood lipids were taken; HOMA was calculated and three standards were applied to select HOMA-IR cases. Three standards to define MS were also used. Medium CIMT was assessed using ultrasonography with automated software. Chi-squared test and stepwise regression were used. Results: Mean age was 11.5 ±1.0 years old; 59% girls; 92.6% pubertal; 72% excess weight. Three standards for MS had prevalence of 24.4% (Cook, 2004), 14.1% (IDF, 2007), 42.9% (De Ferranti, 2004). Three standards for HOMA-IR had the following prevalence: 15.2% (Barja, 2011), 37.4% (Burrows, 2006), 23.0% (De Onis, 2012). Elevated blood pressure and reduced CHDL had significant associations with CIMT ≥ percentile 75. The logistic regression for CIMT ≥ percentile 75 only selected BP ≥ percentile 90 (OR = 2.963) and CHDL < 40 mg/dL (OR = 1.789) Conclusions: None of the various classifications for the MS and the HOMA-IR were selected in the multivariate analysis confirming the previously found influence of increased BP and reduced CHDL on medium CIMT.
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    Association of vitamin D deficiency, season of the year, and latent tuberculosis infection among household contacts
    (2017) Balcells Marty, María Elvira; García Cañete, Patricia; Tiznado, Camila; Villarroel del Pino, Luis A.
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    Ateroesclerosis subclínica y síndrome metabólico en niños
    (2013) Arnáiz Gómez, Pilar; Barja Y., Salesa; Villarroel del Pino, Luis A.; Domínguez, Angélica; Godoy J., Iván; Castillo Valenzuela, Oscar; Farías Jofré, Marcelo Enrique; Mardones, Francisco
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    Attitudes of Medical Students Toward Psychiatry in a Chilean Medical School
    (2014) Valdivieso Fernández, Sergio Andrés; Sirhan Nahum, Marisol; Aguirre, Constanza; Ivelic Zulueta, José Antonio; Aillach Bravo, Emilio Jorge; Villarroel del Pino, Luis A.
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    Autores clásicos en psiquiatría : evaluación de un modelo de enseñanza de la psicopatología para residentes de psiquiatría
    (2015) Valdivieso F., Sergio; Brockering, Walter; Mejías, Macarena; Villarroel del Pino, Luis A.; Gustavo, Maldonado; Sirhan Nahum, Marisol
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    Banding ligation versus beta-blockers for primary prophylaxis of oesophageal variceal bleeding in children. Protocol
    (2013) Gana Ansaldo, Juan Cristóbal; Cifuentes, Lorena; Cerda, Jaime; Villarroel del Pino, Luis A.; Rivera Cornejo, Marcela; Peña Villegas, Alfredo Javier
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    Banding ligation versus sclerotherapy for primary prophylaxis of oesophageal varices in children (Protocol)
    (2015) Gana Ansaldo, Juan Cristóbal; Cifuentes, Lorena; Cerda, Jaime; Villarroel del Pino, Luis A.; Peña Villegas, Alfredo Javier; Torres Robles, R.
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    Banding ligation versus sham or no intervention for primary prophylaxis of oesophageal variceal bleeding in children
    (2015) Gana Ansaldo, Juan Cristóbal; Cifuentes, Lorena; Cerda, Jaime; Villarroel del Pino, Luis A.; Peña Villegas, Alfredo Javier; Rivera Cornejo, M.
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    Beta-blockers versus placebo or no intervention for primary prophylaxis of oesophageal varices in children
    (2015) Gana Ansaldo, Juan Cristóbal; Cifuentes, Lorena; Cerda, Jaime; Villarroel del Pino, Luis A.; Peña Villegas, Alfredo Javier; Torres‐Robles, Romina
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    Bile acids for cholelithiasis
    (2018) Gana Ansaldo, Juan Cristóbal; Gattini Valdés, Daniela Cecilia; Villarroel del Pino, Luis A.; Larraín Castellón, Sebastián; Yap, Jason
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