Browsing by Author "Varga, Eniko"

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    Efficacy of Pembrolizumab Monotherapy for Advanced Gastric/Gastroesophageal Junction Cancer with Programmed Death Ligand 1 Combined Positive Score ≥ 10
    (2021) Wainberg, Zev A.; Fuchs, Charles S.; Tabernero, Josep; Shitara, Kohei; Muro, Kei; Van Cutsem, Eric; Bang, Yung-Jue; Chung, Hyun Cheol; Yamaguchi, Kensei; Varga, Eniko; Chen, Jen-Shi; Hochhauser, Daniel; Thuss-Patience, Peter; Al-Batran, Salah-Eddin; Garrido, Marcelo; Kher, Uma; Shih, Chie-Schin; Shah, Sukrut; Bhagia, Pooja; Chao, Joseph
    Purpose: Pembrolizumab demonstrated efficacy in PD-L1-positive [combined positive score (CPS) >= 1] advanced gastric/gastro-esophageal junction (G/GEJ) cancer in the first-, second-, and third-line setting in KEYNOTE-062, KEYNOTE-061, and KEYNOTE-059, respectively. To better delineate the specificity of CPS as a predictor of dinical outcomes, we analyzed pembrolizumab efficacy in patients with CPS >= 10 in these trials.