Browsing by Author "Vallejos Gálvez, Omar Patricio"

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects
    (2025) Vallejos Gálvez, Omar Patricio; Bueno Ramírez, Susan; Kalergis Parra, Alexis Mikes
    Inflammatory bowel disease (IBD) is a chronic inflammatory disorder that represents a significant public health challenge worldwide. This multifactorial condition results from complex interactions among genetic, environmental, immune, and microbial factors. Some beneficial microbes, known as probiotics, have been identified as promising therapeutic agents for inflammatory conditions, such as IBD. In this review, we explore the potential of probiotics as a therapeutic strategy for managing IBD. Probiotics have shown promise due to their ability to modulate the gut microbiota, regulate histamine levels, and enhance vitamin D metabolism, thereby promoting a tolerant immune profile and reducing inflammation. While the exact mechanisms underlying these benefits remain incompletely understood, probiotics represent a novel and emerging approach for alleviating the exacerbated inflammation characteristic of this disorder.
  • Thumbnail Image
    Item
    The impact of the micronutrient iodine in health and diseases
    (Bellwether Publishing, Ltd., 2020) Opazo, María Cecilia; Riedel, Claudia A.; Coronado, Arrazola Irenice; Vallejos Gálvez, Omar Patricio; Kalergis Parra, Alexis Mikes; Bueno Ramírez, Susan Marcela; Moreno Reyes, Rodrigo; Fardella Bello, Carlos Enrique; Mosso Gómez, Lorena Montserrat
    © 2020 Taylor & Francis Group, LLC.Adequate iodine nutrition is crucial for all mammals by playing his starring role as a component of thyroid hormones, which are key regulators of cellular processes for life such as differentiation, growth, function, and metabolism. Deficiency or excess of iodine in the diet are worldwide highly frequent conditions that are responsible of health problems like hypothyroidism, hypothyroxinemia, goiter, thyroiditis, hyperthyroidism, and autoimmune thyroid diseases among others. The incorporation of iodine in salt or other nutrients resolved the consequences of severe iodine deficiency like goiter, cretinism. However, this strategy in several countries led to other ailments like Hashimoto autoimmune thyroiditis, hyperthyroidism, and hypothyroidism. The goal of this review is to analyze and discuss the different aspects of iodine nutrition for human health comprising its biological role through thyroid hormones, pathogen control, and the regulation of the intestinal microbiota.