Browsing by Author "Torres, J."
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- ItemA promising Electrochemical Test for Evaluating the Hydrocarbon - Type Pollutants Contained in Industrial Waste Soils(2011) Ramirez, V.; Sanchez, J.A.; Hernández P., Glenn; Solis, S.; Torres, J.; Antano, R.; Manríquez M., Juan Manuel; Bustos, E.
- ItemChemical hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles(2020) Hernández Villanueva, Alejandra Andrea; Geng, Y.; Sepúlveda, R.; Solis López, Nancy de las Mercedes; Torres, J.; Arab Verdugo, Juan Pablo; Barrera Martínez, Francisco Javier; Cabrera, D.; Moshage, H.; Arrese, Marco
- ItemDexmedetomidine metabolic clearance is not affected by fat mass in obese patients(2018) Rolle, A.; Paredes, S.; Cortínez Fernández, Luis Ignacio; Anderson, B. J.; Quezada Sanhueza, Nicolás; Solari, S.; Allende, Fidel; Torres, J.; Cabrera, D.; Contreras, V.; Carmona, J.; Ramirez, C.; Oliveros, A. M.; Ibacache Figueroa, Mauricio Enrique
- ItemDiseño de una escala ecográfica predictora de malignidad en nódulos tiroideos: Comunicación preliminar(2009) Domínguez, J.M.; Baudrand, R.; Arteaga, E.; Campusano, C.; González, G.; Mosso, L.; Fardella, C.; Arias, T.; Pizarro, A.; Gómez, M.; Cruz, F.; Torres, J.; Solar, A.; Cavada, G.; NCD Risk Factor Collaboration (NCD-RisC)Background: Thyroid nodules are common and associated to a low risk of malignancy. Their clinical assessment usually includes a fine neddle aspiration biopsy (FNAB). Aim: To identify ultrasonographic characteristics associated to papillary thyroid carcinoma (PTC) and generate a score that predicts the risk of PTC. Material and methods: Retrospective review of all fine needle aspiration biopsies of the thyroid performed in a lapse of two years. Biopsies that were conclusive for PTC were selected and compared with an equal amount of randomly selected biopsies that disclosed a benign diagnosis. Results: One hundred twenty two biopsies of a total of 1,498 were conclusive for PTC. Univariate analysis showed associations with PTC for the presence of micro-calcifications (Odds ratio (OR) 49.2: 95% confidence intervals (CI) 18.7-140.9), solid predominance (OR 25.1; 95% CI 6-220), hypoechogenicity (OR 23.5, 95% CI 6.5-122.6), irregular borders (OR 17, 95% CI 7.2-42.9), lymph node involvement (OR 12.3, 95% CI 2.7-112), central vascularization (OR 12.2, 95% CI 4.8-33.3), local invasion and hyperechogenicity (OR 0.2; CI 95% CI 0.03-0.6). Multivariate analysis disclosed microcalcifications (OR 28.1; CI 95% 8.9-89), hypoechogenicity (OR 9.4; 95% CI 1.5-59.5) and irregular borders (OR 4.7; CI 95% 1.5-15) as the variables independently associated with the presence of PTC. The prevalence of PTC in the presence of the three variables was 97.6% (Likelihood ratio (LR) 45) and 5.4% in their absence (LR 0.06). Conclusions: This scale predicts the presence or absence of PTC using simple ultrasound characteristics.
- ItemEffective Dissolved Oxygen Control Strategy for High-Cell-Density Cultures(2014) Cárcamo, M.; Saa Higuera, Pedro Andrés E.; Torres, J.; Torres, S.; Mandujano, P.; Pérez C., José Ricardo; Agosin T., Eduardo
- ItemHelicobacter pylori Gastritis in Children Is Associated With a Regulatory T-Cell Response(2008) Harris, P.R.; Wright, S.W.; Serrano, C.; Riera, F.; Duarte, I.; Torres, J.; Peña, A.; Rollán, A.; Viviani, P.; Guiraldes, E.; Schmitz, J.M.; Lorenz, R.G.; Novak, L.; Smythies, L.E.; Smith, P.D.
- ItemMicrocarcinoma tiroideo de evolución agresiva(2005) Mosso, L.; Jimenez, M.; Gonzalez, H.; Solar, A.; Torres, J.; Fardella, C.; NCD Risk Factor Collaboration (NCD-RisC)The treatment of papillary thyroid carcinoma of less than 10 mm diameter is a matter of controversy. The incidental finding of papillary microcarcinomas in autopsies is frequent and some authors postulate that these tumors are biologically inactive and should only be observed. We report a 21 years old woman with a papillary thyroid cancer of 6x5x5 mm and bilateral paratracheal metastases, that leas subjected to a total thyroidectomy. She received 200 mCi of radioiodine. Two years after surgery, a new nodule of 9.6 Mm diameter was detected by ultrasound, that was treated with a new dose of 200 1,170 of radioiodine. One year later a suprasternal mass of 2 cm diameter and 3 enlarged lymph nodes were detected. She was subjected to a surgical lymph node dissection of the neck and the biopsy confirmed the presence of cancer. She received a new dose of 300 mCi of radioiodine. The mother of the patient had a 7 mm thyroid nodule that was also a papillary carcinoma.
- ItemOxygen response of the wine yeast Saccharomyces cerevisiae EC1118 grown under carbon-sufficient, nitrogen-limited enological conditions(2012) Aceituno, F. F.; Orellana, M.; Torres, J.; Mendoza, S.; Slater, A. W.; Melo Ledermann, Francisco Javier; Agosin T., EduardoDiscrete additions of oxygen play a critical role in alcoholic fermentation. However, few studies have quantitated the fate of dissolved oxygen and its impact on wine yeast cell physiology under enological conditions. We simulated the range of dissolved oxygen concentrations that occur after a pump-over during the winemaking process by sparging nitrogen-limited continuous cultures with oxygen-nitrogen gaseous mixtures. When the dissolved oxygen concentration increased from 1.2 to 2.7 μM, yeast cells changed from a fully fermentative to a mixed respirofermentative metabolism. This transition is characterized by a switch in the operation of the tricarboxylic acid cycle (TCA) and an activation of NADH shuttling from the cytosol to mitochondria. Nevertheless, fermentative ethanol production remained the major cytosolic NADH sink under all oxygen conditions, suggesting that the limitation of mitochondrial NADH reoxidation is the major cause of the Crabtree effect. This is reinforced by the induction of several key respiratory genes by oxygen, despite the high sugar concentration, indicating that oxygen overrides glucose repression. Genes associated with other processes, such as proline uptake, cell wall remodeling, and oxidative stress, were also significantly affected by oxygen. The results of this study indicate that respiration is responsible for a substantial part of the oxygen response in yeast cells during alcoholic fermentation. This information will facilitate the development of temporal oxygen addition strategies to optimize yeast performance in industrial fermentations.
- ItemPortal Angiogenesis in Chronic Liver Disease Patients Correlates with Portal Pressure and Collateral Formation(2019) Serrano Honeyman, Carolina; Ling, S. C.; Verdaguer, S.; León, M.; Jarufe Cassis, Nicolás; Guerra, J. F.; Pattillo Silva, Juan Carlos; Benítez, C.; Villagrán, A.; Torres, J.; Concha, M.; Villarroel del Pino, Luis A.; Dellepiane, P.; Domínguez, P.; Martínez, J.; Gana Ansaldo, Juan Cristóbal
- ItemRisk of Recurrent Helicobacter pylori Infection 1 Year After Initial Eradication Therapy in 7 Latin American Communities(2013) Morgan, D.; Torres, J.; Sexton, R.; Herrero, R.; Salazar Martínez, E.; Greenberg, E.; Bravo, L.; Ferreccio Readi, Catterina
- ItemRobust State Estimation in Presence of Parametric Uncertainty by NL-PI observers. An Application to Continuous Microbial Cultures(2016) Rodríguez, A. E.; Torres, J.; Pérez C., José Ricardo; Domínguez, A. R.; Luna, R.; Flores, G.
- ItemSynthesis and characterization of poly[bis(3-aminophenyl) diselenide] and poly[bis(3-aminophenyl) diselenide-co-aniline](2003) Sánchez, C. O.; Bustos, C. J.; Valle Delaware la Cortina, María Angélica del; Díaz Alzamora, Fernando Raúl; Torres, J.
- ItemTumores neuroendocrinos del páncreas. Resultados quirúrgicos y sobrevida alejada(2013) Galindo, J.; Gabrielli Nervi, Mauricio; Barros, D.; Moisan, F.; Martínez, M.; Torres, J.; Flores, M.; Guerra Castro, Juan Francisco; Martínez Castillo, Jorge; Jarufe Cassis, Nicolás
