Browsing by Author "Thumm, Nicolas"

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    Autograft versus allograft with or without demineralized bone matrix in posterolateral lumbar fusion in rabbits - Laboratory investigation
    (AMER ASSOC NEUROLOGICAL SURGEONS, 2008) Urrutia, Julio; Thumm, Nicolas; Apablaza, Daniel; Pizarro, Felipe; Zylberberg, Alejandro; Quezada, Felipe
    Object. Posterolateral spinal fusions are performed to treat different spinal disorders. Autograft continues to be the gold standard; it is, however, associated with donor site morbidity and limited sources. Allograft has been used, but has been reported to result in lower fusion rates. Demineralized bone matrix (DBM) has also been used and reportedly increases the fusion rate in a variety of critical defect models. Different forms of DBM are available, not all have been independently studied. To evaluate the effect of a xenogenic DBM added to allograft on the fusion rate of posterolateral lumbar spine arthrodesis the authors designed an experimental study comparing posterolateral fusion rate using autograft, allograft, and allograft plus a xenogenic DBM in a validated animal model.