Browsing by Author "Sanchez, C."

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    Cosmology from cross-correlation of ACT-DR4 CMB lensing and DES-Y3 cosmic shear
    (2024) Shaikh, S.; Harrison, I; van Engelen, A.; Alves, O.; Marques, G. A.; Abbott, T. M. C.; Aguena, M.; Amon, A.; An, R.; Bacon, D.; Battaglia, N.; Becker, M. R.; Bernstein, G. M.; Bertin, E.; Blazek, J.; Bond, J. R.; Brooks, D.; Burke, D. L.; Calabrese, E.; Carnero Rosell, A.; Carretero, J.; Cawthon, R.; Chang, C.; Chen, R.; Choi, A.; Choi, S. K.; da Costa, L. N.; Pereira, M. E. S.; Darwish, O.; Davis, T. M.; Desai, S.; Devlin, M.; Diehl, H. T.; Doel, P.; Doux, C.; Elvin-Poole, J.; Farren, G. S.; Ferraro, S.; Ferrero, I; Ferte, A.; Flaugher, B.; Frieman, J.; Garcia-Bellido, J.; Gatti, M.; Giannini, G.; Giardiello, S.; Gruen, D.; Gruendl, R. A.; Gutierrez, G.; Hill, J. C.; Hinton, S. R.; Hollowood, D. L.; Honscheid, K.; Huffenberger, K. M.; Huterer, D.; James, D. J.; Jarvis, M.; Jeffrey, N.; Jense, H. T.; Knowles, K.; Kim, J.; Kramer, D.; Lahav, O.; Lee, S.; Lima, M.; MacCrann, N.; Madhavacheril, M. S.; Marshall, J. L.; McCullough, J.; Mehta, Y.; Mena-Fernandez, J.; Miquel, R.; Mohr, J. J.; Moodley, K.; Myles, J.; Navarro-Alsina, A.; Newburgh, L.; Niemack, M. D.; Omori, Y.; Pandey, S.; Partridge, B.; Pieres, A.; Malagon, A. A. Plazas; Porredon, A.; Prat, J.; Qu, F. J.; Robertson, N.; Rollins, R. P.; Roodman, A.; Samuroff, S.; Sanchez, C.; Sanchez, E.; Cid, D. Sanchez; Secco, L. F.; Sehgal, N.; Sheldon, E.; Sherwin, B. D.; Shin, T.; Sifon, C.; Smith, M.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Troxel, M. A.; Tutusaus, I; Vargas, C.; Weaverdyck, N.; Wiseman, P.; Yamamoto, M.; Zuntz, J.
    Cross-correlation between weak lensing of the Cosmic Microwave Background (CMB) and weak lensing of galaxies offers a way to place robust constraints on cosmological and astrophysical parameters with reduced sensitivity to certain systematic effects affecting individual surveys. We measure the angular cross-power spectrum between the Atacama Cosmology Telescope (ACT) DR4 CMB lensing and the galaxy weak lensing measured by the Dark Energy Survey (DES) Y3 data. Our baseline analysis uses the CMB convergence map derived from ACT-DR4 and Planck data, where most of the contamination due to the thermal Sunyaev Zel'dovich effect is removed, thus avoiding important systematics in the cross-correlation. In our modelling, we consider the nuisance parameters of the photometric uncertainty, multiplicative shear bias and intrinsic alignment of galaxies. The resulting cross-power spectrum has a signal-to-noise ratio = 7.1 and passes a set of null tests. We use it to infer the amplitude of the fluctuations in the matter distribution (S-8 equivalent to sigma(8) (Omega(m)/0.3)(0.5) = 0.782 +/- 0.059) with informative but well-motivated priors on the nuisance parameters. We also investigate the validity of these priors by significantly relaxing them and checking the consistency of the resulting posteriors, finding them consistent, albeit only with relatively weak constraints. This cross-correlation measurement will improve significantly with the new ACT-DR6 lensing map and form a key component of the joint 6x2pt analysis between DES and ACT.
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    Double pi-pi stacking in 2-[(E)-(3,5-dimethylisoxazol-4-yl)diazenyl]benzoic acid
    (2006) Alvarez-Thon, L.; Bustos, C.; Schott Verdugo, Eduardo Enrique; Sanchez, C.; Ibanez, A.
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    How much survival benefit is necessary for breast cancer patients to opt for adjuvant chemotherapy? Results from a Chilean survey
    (2014) Acevedo Claros, Francisco Nicolás; Sanchez, C.; Jans, J.; Rivera Mercado, Solange; Camus, M.; Besa, P.
    Background: Breast cancer (BC) is the leading cause of cancer death in Chilean women. Adjuvant chemotherapy decreases recurrence and death from BC. The recommendation to indicate chemotherapy is complex. Adjuvant! Online is a valuable computational tool to predict survival benefit obtained with adjuvant systemic therapy. Previous studies in Caucasian patients with BC showed that they are willing to receive chemotherapy for a small benefit. No studies, to our knowledge, have been done in the Hispanic or Latino populations. Methods: We interviewed females with BC who had previously received adjuvant chemotherapy. Age, stage at presentation, time since last chemotherapy, type of chemotherapy, marital status, number of children, and level of education were recorded. We used the graphic representation from Adjuvant! Online to question each patient on how much survival benefit she required to accept chemotherapy. Results: There were 101 women surveyed. The average age was 55.9 (±10.2), 54.5% had involved lymph nodes, 59.4% were married, and 15.8% did not have parity; 62.3% of females accepted chemotherapy for an absolute survival benefit of 1% or less. In a multivariate analysis, younger (p = 0.02) and less-educated patients (p = 0.018) were associated with lower survival benefit required to opt for chemotherapy. Conclusion: In our study, the acceptance of chemotherapy by the Hispanic population requires minimal survival benefit and is in agreement with the Caucasian population reported elsewhere. To our knowledge, our report is the first study that evaluates the perception of Latino patients regarding the benefit of chemotherapy in early BC.
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    NOTCH3 Gene Mutation in a Chilean Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Family
    (2020) Gallardo, A.; Latapiat, V.; Rivera, A.; Fonseca, B.; Roldan, A.; Sandoval, Patricio; Sanchez, C.; Matamala, J.M.
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    Occurrence, source estimation, and risk assessment of Polycyclic Aromatic Hydrocarbons in coastal seawaters from the Quintero Industrial Complex (Valparaiso, Chile)
    (2023) Galban-Mmalagon, C. J.; Zapata, J.; Perez-Venegas, D. J.; Vargas, R.; Latorre-Padilla, N.; Luarte, T.; Ahrendt, C.; Hirmas-Olivares, A.; Gomez-Aburto, V.; Tapia, P.; Isamit, V.; Arce, P.; Sanchez, C.; Pozo, K.
    In the 1960s, the Quintero industrial complex was inaugurated in Chile. This began a history of dramatic anthropo-genic impacts on the Chilean coast. Among the known, we could mention high atmospheric emissions of chemicals due to combustion processes and frequent oil spills. For this reason, we surveyed the concentrations of fifteen EPAPAHs in the surface coastal waters of the Quintero Bay area in 2015. The levels found are in the range of the highest levels when reviewing the literature (0.97 mu g L-1 up to 9.84 mu g L-1). The highest levels were found in the vicinity of the industrial complex and decreased in the other two zones. The concentration of individual compounds significantly ex-ceeds the levels recommended by the EPA (Environmental Protection Agency) and the EU water framework directive (WFD). The risk estimations revealed that PAH concentrations represent high-risk for wildlife. Molecular ratios of PAHs were used to identify the possible sources, being these were mainly of pyrogenic origin, agreeing with an origin in the combustion of wood, coal, grass, and fossil fuels. This study contributes to the first data for surface water in a country's highly impacted industrial coastal area.
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    Prolonged survival of a woman with lung cancer diagnosed and treated with chemotherapy during pregnancy - Review of cases reported
    (ELSEVIER IRELAND LTD, 2008) Garrido, M.; Clavero, J.; Huete, A.; Sanchez, C.; Solar, A.; Alvarez, M.; Orellana, E.
    Lung cancer is the most common cause of cancer death in women in the US, diagnosis during pregnancy is rare and has been reported 34 times. We report a case of a 34-year-old woman with stage III locally advanced lung cancer diagnosed during the 27th week of pregnancy. Chest X-ray and thorax MRI revealed a 9 cm x 7 cm mass in the upper right lung lobe. CT guided FNA biopsy indicated adenocarcinoma. Neoadjuvant chemotherapy was administered with vinorelvine (Navetbine (R)) and cisplatin for three cycles with partial response. At 39 weeks, she delivered a healthy baby. Right upper lobectomy with complete lymphadenectomy was performed 3 weeks later. Final pathology was reported as an adenocarcinoma of 7.5 cm x 6.2 cm with involvement of 16/30 lymph nodes. She received three additional cycles of chemotherapy and radiotherapy. Follow-up with CT scan after 11 months did not show recurrence. (C) 2007 Elsevier Ireland Ltd. Ail rights reserved.