Browsing by Author "Salazar, L."

Now showing 1 - 3 of 3
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    PRACTICES AND BARRIERS TO THE ADOPTION OF DIGITAL TWIN CONSTRUCTION IN LATIN AMERICA
    (Springer Nature, 2025) Martinez, J.G.; Gimenez De Benavides, Zulay Mercedes; Salazar, L.; Alva, L.; Alarcon, L.F.; Yeung, T.; Sacks, R.
    © 2025, International Group for Lean Construction. All rights reserved.The Digital Twin Construction paradigm, built on existing concepts of Lean project production systems, Building Information Modelling, Artificial Intelligence, and Automated data acquisition, proposes a new mode of construction management that leverages real-time insights and predictive analytics to optimise production flow and mitigate risks proactively. Its potential adoption in Latin America has yet to be explored. This study examines current practices and barriers to implementing Digital Twin Construction-based production planning and control systems. A survey was developed and validated through the Delphi method, involving an expert panel to ensure reliability and relevance. According to the survey’s results and experts' opinions, technological, organisational, cultural, and economic factors have impacted the adoption of Digital Twin Construction, including lack of robust digital infrastructure, gaps in knowledge, and resistance to innovation. The research findings provide practical recommendations to support future research and industry efforts.
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    The immunological response and post-treatment survival of DC-vaccinated melanoma patients are associated with increased Th1/Th17 and reduced Th3 cytokine responses
    (2013) Duran Aniotz, C.; Segal, G.; Salazar, L.; Pereda, C.; Falcon, C.; Tempio, F.; Aguilera, R.; Nervi Nattero, Bruno
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    Tumour necrosis factor (TNF)α-308 G/G promoter polymorphism and TNFα levels correlate with a better response to adalimumab in patients with rheumatoid arthritis
    (2006) Cuchacovich, M.; Soto, L.; Edwardes, M.; Gutierrez, M.; Llanos, C.; Pacheco, D.; Sabugo, F.; Alamo, M.; Fuentealba, C.; Villanueva, L.; Gatica, H.; Schiattino, I.; Salazar, L.; Catalan, D.; Valenzuela, O.
    Objective: To investigate the influence of -308 tumour necrosis factor-alpha (TNF alpha) promoter polymorphism and circulating TNF alpha levels in the clinical response to adalimumab treatment in patients with rheumatoid arthritis (RA).