Browsing by Author "SOZA, M"
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- ItemBILATERAL HOMONYMOUS HEMIANOPIA WITH SPARING OF CENTRAL VISION AFTER SUBDURAL-HEMATOMA(1987) SOZA, M; TAGLE, P; KIRKHAM, T; COURT, JA patient with bilateral homonymous hemianopia with preservation of the central vision, spatial disorientation and memory deficits secondary to bilateral occipital and mesial temporal infarctions, is presented. The cerebral damage followed a subdural hematoma with tentorial herniation and compression of both posterior cerebral arteries.
- ItemCALCIUM PARADOX IN SKELETAL-MUSCLES - PHYSIOLOGICAL AND MICROSCOPIC OBSERVATIONS(1986) SOZA, M; KARPATI, G; CARPENTER, SImmersion of rat hemidiaphragms in Ca2+-free Krebs solution (KS) containing Ca2+ chelator in vitro leads to separation of basal lamina from the plasma membrane, as well as transient contracture and rapid loss of twitch response [calcium paradox (CP) phase 1]. Subsequent immersion in regular KS results in necrosis of muscle fibers accompanied by slowly increasing contracture (CP phase 2). This contracture could be presented or reduced by using either Ca2+-free KS or calcium channel blockers, but not by dantrolene sodium, implying that after drastic reduction of extracellular and sarcolemmal Ca2+ during CP phase 1, the sarcolemma has lost its ability to control normal Ca2+ fluxes. Contracture did not develop at 21.degree. C. CP is a convenient model to study calcium-induced muscle cell death and the role of Ca2+ in maintaining sarcolemmal integrity.