Browsing by Author "SMEITINK, JAM"

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    IMMUNOLOCALIZATION OF A 43 KDA PEROXISOMAL MEMBRANE-PROTEIN IN THE LIVER OF PATIENTS WITH GENERALIZED PEROXISOMAL DISORDERS
    (1995) ESPEEL, M; ROELS, F; GIROS, M; MANDEL, H; PELTIER, A; POGGI, F; POLLTHE, BT; SMEITINK, JAM; VANMALDERGEM, L; SANTOS, MJ
    The presence of peroxisomal membrane ghosts was examined in liver biopsies from eleven patients presenting the clinical and biochemical picture of a generalized peroxisomal disorder (Zellweger syndrome, neonatal adrenoleukodystrophy, infantile Refsum disease and variants of these syndromes). A polyclonal antibody raised against the membrane of human liver peroxisomes and recognizing a 43 kDa peroxisomal membrane protein (PMP) was used. In human control liver the antibodies react in a distinct and specific way with the peroxisomal membrane.