Browsing by Author "SANTELICES, LC"

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    CYTOCHEMICAL STUDY OF DISTRIBUTION OF ADENOSINE-TRIPHOSPHATASE IN PANCREAS OF DOG
    (1976) KOENIG, CS; SANTELICES, LC; VIAL, JD
    Dog pancreatic tissue, incubated in a modified Wachstein-Meisel medium, showed 2 different ATPase activities. One of them was located at the apical border of the cells lining the intralobular ducts and of the centroacinar cells and was stimulated by HCO3-, depressed by SCN- and OCN- and completely abolished by CN-. The other was located at the intracellular clefts of the epithelium lining the interlobular ducts and was stimulated by Mg2+. These findings correlated well with the results of incubation of homogenates of fresh and fixed tissues. Their significance with respect to the role of different segments of the duct system in the formation of the pancreatic juice was discussed.