Browsing by Author "Russo, Riccarda"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Lung Opening and Closing during Ventilation of Acute Respiratory Distress Syndrome
    (AMER THORACIC SOC, 2010) Caironi, Pietro; Cressoni, Massimo; Chiumello, Davide; Ranieri, Marco; Quintel, Michael; Russo, Sebastiano G.; Cornejo, Rodrigo; Bugedo, Guillermo; Carlesso, Eleonora; Russo, Riccarda; Caspani, Luisa; Gattinoni, Luciano
    Rationale The effects of high positive end-expiratory pressure (PEEP) strictly depend on lung recruitability, which varies widely during acute respiratory distress syndrome (ARDS). Unfortunately, increasing PEEP may lead to opposing effects on two main factors potentially worsening the lung injury, that is, alveolar strain and intratidal opening and closing, being detrimental (increasing the former) or beneficial (decreasing the latter).