Browsing by Author "Rodríguez J."
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- ItemCardiac dyssynchrony correlates with left ventricular remodeling after myocardial infarctionLa disincronía cardíaca se correlaciona con el remodelado ventricular izquierdo postinfarto agudo al miocardio(2009) McNab P.; Castro P.; Gabrielli L.; Verdejo H.; Quintana J.; Rodríguez J.; Corbalán R.Background: Cardiac dyssynchrony is common in advanced heart failure (HF), but the changes in cardiac synchrony after myocardial infarction (MI) have not been adequately described. Aim: To study the relationship between cardiac synchrony and left ventricular remodeling after acute myocardial infarction. Material and methods: Forty nine patients aged 59±10 years (77% men) with a first episode of a ST segment elevation MI, were studied. Scintigraphic left ventricular function and synchrony analyses were performed at baseline and after a six months follow-up. Determinations were compared with 33 healthy subjects. Results: At baseline, patients with MI had a decreased left ventricular ejection fraction (LVEF) and significant dyssynchrony, when compared with controls. LVEF was 36.4%±10%, left ventricular end-diastolic volume (LVEDV) 127±38 mL, interventricular delay (IEV) 29±35 miliseconds (ms), and intraventricular delay (IAV), 234±89 ms. After 6 months, LVEF significantly improved (38%±10%, p =0.042) without significant changes in LVEDV (129±32 mL, p =0.97), IEV (24±17, p =0.96) or IAV (231±97, p =0.34). At baseline there were significant correlations between IAV and LVEF, and between IAV and LVEDV (r =-0.48, p =0.001 and r =-0.41, p =0.004, respectively). These correlations remained significant after 6 months. There was a positive correlation between IAV and LVEDV changes at six months (r =0.403, p =0.04). Conclusions: The development of cardiac dyssynchrony correlates with adverse left ventricular remodeling after MI.
- ItemConsolidado de recomendaciones del comité asesor de vacunas y estrategias de inmunización-cavei, sobre priorización de vacunación covid-19Consolidated recommendations of the Advisory Committee on Vaccines and Immunization Strategies- on prioritizing COVID-19 vaccination(2021) Dabanch J.; Bastías M.; Endeiza M.L.; Díaz E.; Inostroza J.; Cerda J.; Santillana S.; Rodríguez J.; González C.; Rodríguez M.; Pizarro A.; Dabanch J.; Bastías M.; González C.; Endeiza M.L.; Díaz E.; Inostroza J.; Cerda J.; Santillana S.; Rodríguez J.; Rodríguez M.; Pizarro A.; Dabanch J.© 2021, Sociedad Chilena de Infectologia. All rights reserved.COVID-19 is a global public health issue due to its epidemic nature that, to date, lacks pharmacological treatment. However, some COVID-19 vaccines have been authorized for emergency use, although the duration of their protection, their ability to interrupt viral transmission, and their efficacy against emerging variants of SARS-CoV-2 are being studied. Chile's SARS-CoV-2 vaccination campaign required design and planning, like any other campaign. This process included the prioritization of risk groups for vaccination given the limited supply of COVID-19 vaccines globally. Throughout 2020, CAVEI issued recommendations on the prioritization of population groups to be vaccinated against SARS-CoV-2 in response to different needs and in accordance with available evidence. These recommendations are consolidated in Table 1 in this report. In summary, it was recommended that healthcare workers, people in long-term residences and essential State personnel be vaccinated in phase 1. In phase 2, persons over 65 years of age and people with comorbidities. In phase 3, essential tasks workers and, lastly, the general population.