Browsing by Author "Riveros, Rodrigo"

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    Applauding with Closed Hands: Neural Signature of Action-Sentence Compatibility Effects
    (PUBLIC LIBRARY SCIENCE, 2010) Aravena, Pia; Hurtado, Esteban; Riveros, Rodrigo; Cardona, Juan Felipe; Manes, Facundo; Ibanez, Agustin
    Background: Behavioral studies have provided evidence for an action-sentence compatibility effect (ACE) that suggests a coupling of motor mechanisms and action-sentence comprehension. When both processes are concurrent, the action sentence primes the actual movement, and simultaneously, the action affects comprehension. The aim of the present study was to investigate brain markers of bidirectional impact of language comprehension and motor processes.
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    The face and its emotion: Right N170 deficits in structural processing and early emotional discrimination in schizophrenic patients and relatives
    (ELSEVIER IRELAND LTD, 2012) Ibanez, Agustin; Riveros, Rodrigo; Hurtado, Esteban; Gleichgerrcht, Ezequiel; Urquina, Hugo; Herrera, Eduar; Amoruso, Lucia; Martin Reyes, Migdyrai; Manes, Facundo
    Previous studies have reported facial emotion recognition impairments in schizophrenic patients, as well as abnormalities in the N170 component of the event-related potential. Current research on schizophrenia highlights the importance of complexly-inherited brain-based deficits. In order to examine the N170 markers of face structural and emotional processing, DSM-IV diagnosed schizophrenia probands (n = 13), unaffected first-degree relatives from multiplex families (n = 13), and control subjects (n = 13) matched by age, gender and educational level, performed a categorization task which involved words and faces with positive and negative valence. The N170 component, while present in relatives and control subjects, was reduced in patients, not only for faces, but also for face-word differences, suggesting a deficit in structural processing of stimuli. Control subjects showed N170 modulation according to the valence of facial stimuli. However, this discrimination effect was found to be reduced both in patients and relatives. This is the first report showing N170 valence deficits in relatives. Our results suggest a generalized deficit affecting the structural encoding of faces in patients, as well as the emotion discrimination both in patients and relatives. Finally, these findings lend support to the notion that cortical markers of facial discrimination can be validly considered as vulnerability markers. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
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    The relationship of clinical, cognitive and social measures in schizophrenia: A preliminary finding combining measures in probands and relatives
    (HINDAWI LTD, 2012) Huepe, David; Riveros, Rodrigo; Manes, Facundo; Couto, Blas; Hurtado, Esteban; Cetkovich, Marcelo; Escobar, Maria; Vergara, Viviana; Parrao, Teresa; Ibanez, Agustin
    This study examines performance of schizophrenia patients, unaffected relatives and controls in social cognition, cognitive and psychiatric scales looking for possible markers of vulnerability in schizophrenia. Performance of schizophrenia patients from multiplex families, first-degree relatives, and matched controls was compared and, subsequently, discriminant analysis method was used for identifying the best predictors for group membership. By using Multigroup Discriminant Analyses on the three groups, the best predictors were PANSS, Premorbid Adjustment Scale, Faux Pas test, and a face/emotion categorizing task. This model obtained 82% correct global classification, suggesting that the combination of psychiatric scales and neuropsychological/social cognition tasks are the best approach for characterizing this disease. Although preliminary, our results suggest that social cognition tasks are robust markers of schizophrenia family impairments, and that combining clinical, social and neuropsychological measures is the best approach to asses patients and relatives vulnerability.