Browsing by Author "Riquelme, A"

Now showing 1 - 5 of 5
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    Histological resolution of steatohepatitis after iron depletion
    (2004) Riquelme, A; Soza, A; Nazal, L; Martínez, G; Kolbach, M; Patillo, A; Arellano, M; Duarte, I; Martínez, J; Molgó, M; Arrese, M
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    Increased orocecal transit time in patients with nonalcoholic fatty liver disease
    (2005) Soza, A; Riquelme, A; González, R; Alvarez, M; Pérez-Ayuso, RM; Glasinovic, JC; Arrese, M
    Intestinal bacterial overgrowth (IBO) has been suggested to play a pathogenic role in patients with nonalcoholic fatty liver disease (NAFLD). Delayed intestinal transit may contribute to IBO development. Ten nondiabetic patients with NAFLD and abnormal liver enzymes were recruited. Ten healthy individuals, matched by sex, age, and body mass index, were used as controls. Orocecal transit time (OCTT) was measured by the lactulose breath test. Anti-endotoxin core antibodies (EndoCAb) were determined. The effect of oral norfloxacin (400 mg BID during 2 weeks) on liver enzymes, lactulose breath test, and EndoCAb was also studied. NAFLD patients had higher basal breathed H, and prolonged OCTT compared to controls (127 +/- 61 vs. 57 +/- 23 min, respectively; P=0.0037). EndoCAb titers were similar in NAFLD patients and controls. Norfloxacin administration had no effect on ALT levels, lactulose breath test, or EndoCAb titers in patients with NAFLD. The present data show evidence of deranged intestinal motility in nondiabetic patients with NAFLD and support the hypothesis that NAFLD could be linked to endotoxin-induced liver damage of intestinal origin.
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    Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass
    (2005) Boza, C; Riquelme, A; Ibañez, L; Duarte, I; Norero, E; Viviani, P; Soza, A; Fernandez, JI; Raddatz, A; Guzman, S; Arrese, M
    Background: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are conditions gaining increasing recognition in hepatology as a potential cause of cirrhosis and end-stage liver disease. Obesity is one of the main risk factors. The aims of this study were to determine the frequency of NAFLD in obese patients and to identify variables that predict NASH.
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    Successful liver transplantation and delivery in a woman with fulminant hepatic failure occurring during the second trimester of pregnancy
    (WILEY, 2006) Jarufe, N; Soza, A; Perez Ayuso, RM; Poblete, JA; Gonzalez, R; Guajardo, M; Hernandez, V; Riquelme, A; Arrese, M; Martinez, J
    Background: Severe liver dysfunction occurring during pregnancy is an unusual but dramatic event that poses special technical and ethical issues because it involves two lives. Methods an Results: We report the case of a 35-year-old woman with cryptogenic fulminant hepatic failure who underwent successful orthotopic liver transplantation at 22 weeks of pregnancy. After a relatively uneventful post-operative course she delivered a normal offspring at the 27th week of gestation. There were no obstetrical complications and neonatal outcome was excellent. After a year of follow-up, the patient is doing well,and the newborn has exhibited normal psychomotor and weight/height development. Conclusions: This case illustrates the challenge of treating fulminant hepatic failure during pregnancy and demonstrates that liver transplantation is a feasible therapeutic option for treatment of patients with this condition, allowing successful completion of pregnancy.
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    Sun exposure behaviors and knowledge among Chileans
    (SOC MEDICA SANTIAGO, 2005) Molgo, M; Castillo, C; Valdes, R; Romero, W; Jeanneret, V; Cevo, T; Torres, C; Silva, P; Flores, L; Riquelme, A; Ayala, MF; Gonzalez, F; Hasbun, MT; Baladron, MJ
    Background: Ultraviolet light exposure has a pathogenic effect on the development of skin cancer whose prevalence increases worldwide. In Chile and the rest of the world, preventive educational campaigns are carried out to change high risk sun exposure behaviors. Aim To study the behavior of the Chilean population towards skin cancer prevention and to identify erroneous preventive practices and concepts. Material and methods: A survey containing 17 questions about sun exposure behaviors, photoprotective measures and knowledge about ultraviolet radiation and skin cancer was used. It was applied during January and February 2004, to 1,143 subjects (mean age 30 years, 409 males), taking vacations in beach resorts in Chile. Results: The hours of higher sun, exposure ranged from 12 AM to 4 PM. Thirty seven percent of subjects were exposed more than 2 hours during this high risk lapse. Women and subjects aged less than 25 years were Those with the riskiest behaviors. Fifty four percent used some type of photoprotection and 50% used ocular protection. Seventy percent used creams with sun screen and 74% used a sun protection factor higher than 15. Seventy percent applied The sun screen as recommended. Thirty eight percent had at least one sun burn in the last two years. More than 90% of subjects were aware of the relationship between sun exposure and skin cancer but 60% did not know the hours of higher ultraviolet radiation. The information about sun exposure was obtained from television in 57% of surveyed individuals. Conclusions: More educational campaigns about the risk of sun exposure are needed to reduce risky behaviors in the Chilean population.