Browsing by Author "Retamal Lucero, Mauricio Antonio"
Now showing 1 - 4 of 4
Results Per Page
Sort Options
- ItemFGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels(2010) Garre, J. M.; Retamal Lucero, Mauricio Antonio; Sáez, Juan Carlos
- ItemImpact of Microglial Activation on Astroglial Connexin Expression and Function in Brain Inflammation(Taylor and Francis publisher, 2013) Giaume, Christian; Froger, Nicolás; Orellana Roca, Juan Andrés; Retamal Lucero, Mauricio Antonio; Saéz Carreño, Juan CarlosThe central nervous system (CNS) is capable of dynamic immune and inŽammatory responses mediated by the activation of microglia, the brain resident macrophage population, and astrocyte reactivity. A growing body of evidence shows that the innate immune response exerts a dichotomous role in the brain. Under physiological conditions, microglia exhibit a resting phenotype that is associated with the production of anti-inŽammatory and neurotrophic factors. Microglia shift to an activated phenotype in response to a wide range of insults that activate speciŸc signaling pathways, thereby promoting an inŽammatory response necessary to further engage the immune system. The sustained inŽammation resulting in brain injury and pathology
- ItemOpening of connexin 43 hemichannels is increased by lowering intracellular redox potential(2007) Retamal Lucero, Mauricio Antonio; Sáez, Juan Carlos
- ItemOpening of pannexin- and con nexin-based channels increases the excitability of nodose ganglion sensory neurons(2014) Retamal Lucero, Mauricio Antonio; Sáez Pedraza, Pablo José; Sáez, Juan Carlos