DSpace Angular :: Browsing by Author "Recabarren Gajardo, Gonzalo Iván"

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Derivados de adamantiloxadiazoles y sus solvatos, hidratos y sales farmaceuticamente aceptables del mismo, composición farmacéutica que los comprende, proceso de síntesis, útiles como inhibidores efectivos y selectivos de la actividad reductasa de la enzima 11-BETA HIDROXIESTEROIDE deshidrogenasa tipo 1 (11B- HSD1)) y selectivos de la actividad reductasa de la enzima 11-BETA deshidrogenasa tipo 1 (11Β-HSD1) (Australia, concesión n° 2019440945)
Fardella Bello, Carlos Enrique; Lagos Arévalo, Carlos Fernando; Vecchiola Cárdenas, Andrea Paola; Allende Sanzana, Fidel Alejandro; Diethelm Varela, Benjamín Manuel; Recabarren Gajardo, Gonzalo Iván; González Cisterna, Pablo Marcelo
Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands
(2013) Espinosa Bustos, Christian; Iturriaga Vásquez, Patricio; Lagos, Carlos; Mella Raipán, Jaime; Pessoa Mahana, Carlos David; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Romero Parra, Javier Hernán
A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 compounds displayed high affinitie