Browsing by Author "Ranieri, Vito Marco"

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    Anatomical and functional intrapulmonary shunt in acute respiratory distress syndrome
    (LIPPINCOTT WILLIAMS & WILKINS, 2008) Cressoni, Massimo; Caironi, Pietro; Polli, Federico; Carlesso, Eleonora; Chiumello, Davide; Cadringher, Paolo; Quintel, Micheal; Ranieri, Vito Marco; Bugedo, Guillermo; Gattinoni, Luciano
    Objectives. The lung-protective strategy employs positive end expiratory pressure to keep open otherwise collapsed lung regions (anatomical recruitment). Improvement in venous admixture with positive end-expiratory pressure indicates functional recruitment to better gas exchange, which is not necessarily related to anatomical recruitment, because of possible global/regional perfusion modifications. Therefore, we aimed to assess the value of venous admixture (functional shunt) in estimating the fraction of nonaerated lung tissue (anatomical shunt compartment) and to describe their relationship.