Browsing by Author "Ramchandani, Avinash"
Now showing 1 - 4 of 4
Results Per Page
Sort Options
- ItemA nomogram for predicting complications in patients with solid tumours and seemingly stable febrile neutropenia(2016) Jimenez Fonseca, Paula; Carmona-Bayonas, Alberto; Matos Garcia, Ignacio; Marcos, Rosana; Castanon, Eduardo; Antonio, Maite; Font, Carme; Biosca, Merce; Blasco, Ana; Lozano, Rebeca; Ramchandani, Avinash; Beato, Carmen; Martinez de Castro, Eva; Espinosa, Javier; Martinez-Garcia, Jeronimo; Ghanem, Ismael; Hernando Cubero, Jorge; Aragon Manrique, Isabel; Garcia Navalon, Francisco; Sevillano, Elena; Manzano, Aranzazu; Virizuela, Juan; Garrido, Marcelo; Mondejar, Rebeca; Angeles Arcusa, Maria; Bonilla, Yaiza; Perez, Quionia; Gallardo, Elena; del Carmen Soriano, Maria; Cardona, Merce; Sanchez Lasheras, Fernando; Jesus Cruz, Juan; Ayala, FranciscoBackground: We sought to develop and externally validate a nomogram and web-based calculator to individually predict the development of serious complications in seemingly stable adult patients with solid tumours and episodes of febrile neutropenia (FN).
- ItemA nomogram for predicting serious complications in patients with solid tumors and apparently stable febrile neutropenia: prospective data on 781 consecutive episodes from the FINITE study(2014) Ghanem, Ismael; Rebollo, Maite Antonio; Garrido, Marcelo; Martínez, Jerónimo; Font, Carme; Ramchandani, Avinash; Biosca, Merce; Beato, Carmen; Martínez de Castro, Eva; Castanon, Eduardo; Virizuela Echaburu, Juan; Espinosa, Javier; Sevillano, Elena; Aragon Manrique, Isabel; Cardona, Merce; Mondejar, Rebeca; Baron, Francisco; Acevedo Claros, Francisco Nicolás; Jiménez-Fonseca, Paula; Carmona Bayonas, AlbertoBackground: An accurate estimate of the likelihood of serious complications in patients with otherwise apparently stable febrile neutropenia (FN) may assist in decision-making regarding individualized therapy. Our group has developed a prognostic score for predicting complications in patients with solid tumors and apparently stable episodes called CISNE (Clinical Index for Stable Febrile Neutropenia). The purpose of this study is to present a nomogram based on the previously mentioned index in a broader dataset of patients. Methods: FINITE is a prospective and multicenter study which aims to investigate prognostic factors and outcomes of FN episodes with clinical stability at first assessment, defined as events without acute organ dysfunction, vital signs abnormalities or major infections. We performed a nomogram based on the CISNE score which includes the following prognostic variables: ECOG PS≥2, chronic obstructive pulmonary disease, cardiovascular disease, mucositis NCI grade ≥2, monocytes <200/mm3 and stress-induced hyperglycemia. A calibration plot was used to analyze the accuracy of this multivariate nomogram. Results: From October 2012 to December 2013, 781 patients with apparently stable FN were recruited in 21 Spanish hospitals. The rate of infection-related complications and death was 15.6% (95% confidence interval [CI], 12.9-18.6%) and 1.7% (95% CI, 0.98%-3.01%). A nomogram was designed according to the CISNE score. The area under the ROC curve was 0.836 (95% CI, 0.808-0.861). The observed and predicted probabilities also matched closely. Conclusions: Our group has developed a user-friendly nomogram for predicting complications in patients with apparently stable FN. This nomogram may be particularly useful to prevent premature discharges of cancer patients starting inpatient management.
- ItemEfficacy and safety of chemotherapy in older versus non-older patients with advanced gastric cancer:. A real-world data, non-inferiority analysis(2018) Visa, Laura; Jimenez-Fonseca, Paula; Asensio Martinez, Elena; Hernandez, Raquel; Custodio, Ana; Garrido, Manuel; Viudez, Antonio; Buxo, Elvira; Echavarria, Ignacio; Maria Cano, Juana; Macias, Ismael; Mangas, Montserrat; Martinez de Castro, Eva; Garcia, Teresa; Alvarez Mancenido, Felipe; Fernandez Montes, Ana; Azkarate, Aitor; Longo, Federico; Diaz Serrano, Asuncion; Lopez, Carlos; Hurtado, Alicia; Cerda, Paula; Serrano, Raquel; Gil-Negrete, Aitziber; Martin Carnicero, Alfonso; Pimentel, Paola; Ramchandani, Avinash; Carmona-Bayonas, AlbertoObjective: Advanced gastric cancer (AGC) is a common neoplasm in older adults. Nevertheless, there are few specific management data in the literature. The aim of this study was to assess non-inferiority of survival and efficacy-related outcomes of chemotherapy used in older vs non-older patients with ACC
- ItemExternal validity of docetaxel triplet trials in advanced gastric cancer: Are there patients who still benefit?(2020) Jiménez Fonseca, Paula; Carmona Bayonas, Alberto; Martínez de Castro, Eva; Custodio, Ana; Pericay Pijaume, Carles; Hernández, Raquel; Aguado, Gema; Castro Unanua, Natalia; Cano, Juana María; López, Flora; Garrido Salvo, Marcelo Adán; Fernández Montes, Ana; Visa, Laura; Sánchez Cánovas, Manuel; Limón, María Luisa; Martínez Lago, Nieves; Pimentel, Paola; Hurtado, Alicia; Azkárate, Aitor; Longo, Federico; Diez, Marc; Arias Martinez, Aranzazu; Sauri, Tamara; Carnicero, Alfonso Martín; Mangas, Monserrat; Martín Richard, Marta; Granja, Mónica; Ramchandani, Avinash; Hernández Pérez, Carolina; Cerdá, Paula; Gil Negrete, Aitziber; Calvo, Mariona; Vidal Tocino, Rosario; Gallego, Javier