Browsing by Author "Perret, Cecilia"

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    Age as Risk Factor for Death from Pandemic (H1N1) 2009, Chile
    (CENTERS DISEASE CONTROL, 2011) Dabanch, Jeannette; Perret, Cecilia; Najera, Manuel; Gonzalez, Claudia; Guerrero, Andrea; Olea, Andrea; Fasce, Rodrigo; Morales, Cecilia; Vega, Jeanette; Advisory Comm Chilean Minist Hlth
    Pandemic (H1N1) 2009 affected Chile during the winter of 2009. The hospitalization rate was 0.56% overall and 3.47% for persons >= 60 years of age at risk for severe disease and death independent of concurrent conditions. Age >= 60 years was the major risk factor for death from pandemic (H1N1) 2009.
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    Anaplasma platys in dogs, Chile
    (CENTER DISEASE CONTROL, 2007) Abarca, Katia; Lopez, Javier; Perret, Cecilia; Guerrero, Javier; Godoy, Paula; Veloz, Ana; Valiente Echeverria, Fernando; Leon, Ursula; Gutjahr, Constanza; Azocar, Teresa
    We conducted a 16S rRNA nested PCR for the genus Ehrlichia and Ehrlichia spp. with blood samples from 30 ill dogs in Chile. Phylogenetic analysis was performed by using groESL gene amplification. We identified Anaplasma platys as 1 of the etiologic agents of canine ehrlichiosis.
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    Asociación temporal entre la circulación de virus respiratorios y hospitalizaciones por enfermedad de Kawasaki
    (Sociedad Chilena de Infectologia, 2021) Aguirre, Daniela; Cerda, Jaime; Perret, Cecilia; Borzutzky Schachter, Arturo; Hoyos-Bachiloglu
    © 2021, Sociedad Chilena de Infectologia. All rights reserved.Background: The etiology of Kawasaki disease (KD) is unknown. It is believed that viral infections could trigger the disease in susceptible patients. Aim: To study the temporal association between the circulation of respiratory viruses and KD hospitalizations in the Metropolitan Region (MR), Chile, between 2010-2017. Methods: Ecologic study consisting of a review of KD cases in children under 18 years of age based on hospital discharges. The circulation of respiratory viruses was analyzed using the report of the metropolitan surveillance network. Moving averages for KD (MAKD) and respiratory viruses (MARV) were used. Results: 14,902 cases of respiratory virus infections were recorded between 2010-2017. A direct correlation was found between MARV-respiratory syncytial virus (RSV) of one month and year and MAKD of the subsequent month (correlation coefficient (ρ) = +0.441; p < 0.001). A similar association was found for MARV-influenza A (FLU A) (ρ = + 0.362; p < 0.001). MARV-influenza B (FLU B) and MARV-metapneumovirus (MPV) had direct correlations with MAKD (ρ = +0.443; p < 0.001 and ρ = +0.412; p < 0.001, respectively), being FLU B contemporary in month and year with KD, and MPV presenting a one-month lag. Conclusion: There is a direct temporal correlation between RSV, FLU A, FLU B and MPV circulation and KD in children from RM, Chile.
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    Fatal Yellow Fever in Travelers to Brazil, 2018
    (CENTERS DISEASE CONTROL, 2018) Hamer, Davidson H.; Angelo, Kristina; Caumes, Eric; van Genderen, Perry J. J.; Florescu, Simin A.; Popescu, Corneliu P.; Perret, Cecilia; McBride, Angela; Checkley, Anna; Ryan, Jenny; Cetron, Martin; Schlagenhauf, Patricia
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    Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche
    (SOC MEDICA SANTIAGO, 2011) Perret, Cecilia; Viviani, Tamara; Pena, Anamaria; Abarca, Katia; Ferres, Marcela
    Background: Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism. Aim: To determine the source of Pertussis infection in infants aged six months or less in Chile. Material and Methods: Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polymerase chain reaction (PCR). Clinical and demographic data were analyzed. Results: Respiratory symptoms were present in 20 (77%) contacts, being cough the most common. Pertussis cases were identified in every household and in 18 (72%) of the household members. Four members with B.pertussis were asymptomatic. Source of infection was identified in 80% (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PR and their cough duration was significantly shorter compared to primary cases with negative PER. Conclusions: B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants. (Rev Med Chile 2011; 139: 448-454).
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    Illness in Children After International Travel: Analysis From the GeoSentinel Surveillance Network
    (AMER ACAD PEDIATRICS, 2010) Hagmann, Stefan; Neugebauer, Richard; Schwartz, Eli; Perret, Cecilia; Castelli, Francesco; Barnett, Elizabeth D.; Stauffer, William M.; GeoSentinel Surveillance Network
    OBJECTIVE: By using a large, multicenter database, we investigated the characteristics and morbidities of 1591 children returning from 218 global destinations and presenting for care in 19 countries.
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    Intestinal protozoa in returning travellers: a GeoSentinel analysis from 2007 to 2019
    (2024) Weitzel, Thomas; Brown, Ashley; Libman, Michael; Perret, Cecilia; Huits, Ralph; Chen, Lin; Leung, Daniel T.; Leder, Karin; Connor, Bradley A.; Menendez, Marta D.; Asgeirsson, Hilmir; Schwartz, Eli; Salvador, Fernando; Malvy, Denis; Saio, Mauro; Norman, Francesca F.; Amatya, Bhawana; Duvignaud, Alexandre; Vaughan, Stephen; Glynn, Marielle; Angelo, Kristina M.
    Background Prolonged diarrhoea is common amongst returning travellers and is often caused by intestinal protozoa. However, the epidemiology of travel-associated illness caused by protozoal pathogens is not well described. Methods We analysed records of returning international travellers with illness caused by Giardia duodenalis, Cryptosporidium spp., Cyclospora cayetanensis or Cystoisospora belli, reported to the GeoSentinel Network during January 2007-December 2019. We excluded records of travellers migrating, with an unascertainable exposure country, or from GeoSentinel sites that were not located in high-income countries. Results There were 2517 cases, 82.3% giardiasis (n = 2072), 11.4% cryptosporidiosis (n = 287), 6.0% cyclosporiasis (n = 150) and 0.3% cystoisosporiasis (n = 8). Overall, most travellers were tourists (64.4%) on long trips (median durations: 18-30 days). Cryptosporidiosis more frequently affected people < 18 years (13.9%) and cyclosporiasis affected people >= 40 years (59.4%). Giardiasis was most frequently acquired in South Central Asia (45.8%) and sub-Saharan Africa (22.6%), cryptosporidiosis in sub-Saharan Africa (24.7%) and South-Central Asia (19.5%), cyclosporiasis in South East Asia (31.3%) and Central America (27.3%), and cystoisosporiasis in sub-Saharan Africa (62.5%). Cyclosporiasis cases were reported from countries of uncertain endemicity (e.g. Cambodia) or in countries with no previous evidence of this parasite (e.g. French Guiana). The time from symptom onset to presentation at a GeoSentinel site was the longest amongst travellers with giardiasis (median: 30 days). Over 14% of travellers with cryptosporidiosis were hospitalized. Conclusions This analysis provides new insights into the epidemiology and clinical significance of four intestinal protozoa that can cause morbidity in international travellers. These data might help optimize pretravel advice and post-travel management of patients with travel-associated prolonged gastrointestinal illnesses. This analysis reinforces the importance of international travel-related surveillance to identify sentinel cases and areas where protozoal infections might be undetected or underreported.
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    Latin America: Situation and preparedness facing the multi-country human monkeypox outbreak
    (2022) Rodriguez Morales, Alfonso J.; Lopardo, Gustavo; Verbanaz, Sergio; Orduna, Tomás; Lloveras, Susana; Azeñas Burgoa, José María; Escalera-Antezana, Juan Pablo; Alvarado Arnez, Lucia Elena; Naime Barbosa, Alexandre; Diaz Quijano, Fredi; Cimerman, Sergio; Souza Chaves, Tania do Socorro; Rodriguez Morales, Andrea G.; Perret, Cecilia; Méndez, Claudio A.; Riera, Jorge A.; Bonilla Aldana, D.Katterine; Camacho Moreno, Germán; Mendoza, Henry; Rodriguez Sabogal, IvanArturo
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    Unraveling the unparalleled 2024 epidemic of Dengue in the Americas
    (2024) Rodriguez-Morales, Alfonso J.; Montenegro-Idrogo, Juan J.; Celis-Salinas, Juan-Carlos; Angerami, Rodrigo; Villamil-Gomez, Wilmer E.; Sarute, Nicolas; Orduna, Tomas; Perret, Cecilia; Rodriguez-Enciso, Hernan D.; Savio-Larriera, Eduardo; Risquez, Alejandro; Forero-Pena, David A.; Ulloa-Gutierrez, Rolando; Cabrera, Maritza; Cimerman, Sergio; Sah, Ranjit; Acosta-Espana, Jaime D.; Navarro, Juan-Carlos; Sandoval, Nancy; Suarez, Jose A.
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    Yellow fever vaccination for Chilean tourists visiting Brazil. Practical considerations
    (SOC CHILENA INFECTOLOGIA, 2018) Weitzel, Thomas; Perret, Cecilia; Valdivieso, Francisca; Abarca, Katia; Vial, Pablo
    Due to the recent yellow fever outbreak affecting the costal region of Brazil, including main touristic destinations, there is a high demand of yellow fever vaccination. This publication addresses the most relevant practical issues regarding this vaccine for tourists visiting Brazil and aims to serve as a guideline for non-expert physicians in Chile and elsewhere.