Browsing by Author "Patz, Samuel"

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    Quantitative Assessment of Bronchial Wall Attenuation With Thin-Section CT: An Indicator of Airflow Limitation in Chronic Obstructive Pulmonary Disease
    (AMER ROENTGEN RAY SOC, 2010) Yamashiro, Tsuneo; Matsuoka, Shin; Estepar, Raul San Jose; Dransfield, Mark T.; Diaz, Alejandro; Reilly, John J.; Patz, Samuel; Murayama, Sadayuki; Silverman, Edwin K.; Hatabu, Hiroto; Washko, George R.
    OBJECTIVE. The purpose of this study was to evaluate the relation between bronchial wall attenuation on thin-section CT images and airflow limitation in persons with chronic obstructive pulmonary disease. SUBJECTS AND
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    Quantitative CT Measurement of Cross-sectional Area of Small Pulmonary Vessel in COPD: Correlations with Emphysema and Airflow Limitation
    (ELSEVIER SCIENCE INC, 2010) Matsuoka, Shin; Washko, George R.; Dransfield, Mark T.; Yamashiro, Tsuneo; Estepar, Raul San Jose; Diaz, Alejandro; Silverman, Edwin K.; Patz, Samuel; Hatabu, Hiroto
    Rationale and Objectives: Pulmonary vascular alteration is one of the characteristic features of chronic obstructive pulmonary disease (COPD). Recent studies suggest that vascular alteration is closely related to endothelial dysfunction and may be further influenced by emphysema. However, the relationship between morphological alteration of small pulmonary vessels and the extent of emphysema has not been assessed in vivo. The objectives of this study are: to evaluate the correlation of total cross-sectional area (CSA) of small pulmonary vessels with the extent of emphysema and airflow obstruction using CT scans and to assess the difference of total CSA between COPD phenotypes.