Browsing by Author "Olmos Borzone, Roberto Ignacio"

Now showing 1 - 10 of 10
  • Thumbnail Image
    Item
    Cholestasis secondary to hyperthyroidism in Graves' disease : Report of one case
    (2020) Barra, M. I.; Olmos Borzone, Roberto Ignacio; Barrera Martínez, Francisco José; Mosso Gómez, Lorena; Domínguez Ruiz-Tagle, José Miguel
    Hyperthyroidism can induce elevation in several liver function tests including aminotransferases, alkaline phosphatases and, less frequently, serum bilirubin. These alterations are usually mild and asymptomatic. We report a 26 year-old male presenting with palpitations, progressive jaundice, choluria and generalized itching. Laboratory tests were compatible with hyperthyroidism and a mild elevation of bilirubin, alkaline phosphatases and gamma glutamyl transpeptidase. A liver biopsy showed portal hepatitis with canalicular cholestasis. The patient was treated temporarily with glucocorticoids, cholestyramine and betablockade. Thereafter, he was treated with radioactive iodine, after which serum bilirubin decreased steadily until normalization in ten weeks.
  • No Thumbnail Available
    Item
    Clinical Update on Congenital Adrenal Hyperplasia: Recommendations from a Multidisciplinary Adrenal Program
    (2023) Uslar Nawrath, Thomas Hermann; Olmos Borzone, Roberto Ignacio; Martinez Aguayo, Alejandro; Baudrand Biggs, René
    Congenital adrenal hyperplasia (CAH) is a common genetic disorder in endocrinology, especially its milder clinical presentation, often caused by a partial or total deficiency of the 21-hydroxylase enzyme located in the adrenal cortex. CAH is characterized by the overproduction of androgen, along with variable degrees of cortisol and aldosterone deficiency. The age at diagnosis can provide some information about underlying mutations, with those diagnosed at birth/early infancy more likely to have severe enzymatic defects, which may include adrenal insufficiency, sexual development disorders, short stature in adulthood, hirsutism, and a higher risk for metabolic syndrome and infertility. Non-classic CAH, a milder form of CAH, is usually manifested later in life and is a common differential diagnosis of Polycystic Ovary Syndrome and should be actively evaluated during initial studies of clinical or biochemical hyperandrogenism. The main goals of CAH treatment are hormone supplementation for severe cases, controlling adrenal androgen overproduction to minimize long-term side effects, managing fertility and genetic counseling, and optimizing patients' quality of life.
  • Thumbnail Image
    Item
    Discriminative Capacity of CT Volumetry to Identify Autonomous Cortisol Secretion in Incidental Adrenal Adenomas
    (ENDOCRINE SOC, 2022) Olmos Borzone, Roberto Ignacio; Mertens Folch, Nicolas Andres; Vaidya, Anand; Uslar Nawrath, Thomas Hermann; Fernández Walker, Paula Soledad; Guarda Vega, Francisco; Zuñiga, Alvaro; San Francisco Reyes, Ignacio Felipe; Huete Garin, Isidro Alvaro; Baudrand Biggs, Rene Felipe
    Context: Incidentally discovered adrenal adenomas are common. Assessment for possible autonomous cortisol excess (ACS) is warranted for all adrenal adenomas, given the association with increased cardiometabolic disease.
  • Thumbnail Image
    Item
    Gestational diabetes and pre-pregnancy overweight: Possible factors involved in newborn macrosomia
    (2012) Olmos Coelho, Pablo Roberto; Borzone, Gisella; Olmos Borzone, Roberto Ignacio; Valencia, Claudio Nicolás; Bravo, Felipe Andrés; Hodgson Bunster, María Isabel; Belmar Jones, Cristián Gastón; Poblete Lizana, José Andrés; Escalona, Manuel Orlando; Gómez, Bernardita
  • Thumbnail Image
    Item
    In properly selected patients with differentiated thyroid cancer, antithyroglobulin antibodies decline after thyroidectomy and their sole presence should not be an indication for radioiodine ablation
    (2019) Zavala, L.F.; Barra, M.I.; Olmos Borzone, Roberto Ignacio; Tuttle, M.; Gonzalez, H.; Droppelmann, Nicolás; Mosso Gómez, Lorena; Domínguez Ruiz-Tagle, José Miguel
  • Thumbnail Image
    Item
    Metástasis pancreática como debut de carcinoma papilar de tiroides : caso clínico y revisión del perfil clínico patológico y molecular
    (2020) Uslar, T.; Chahuán, J.; Olmos Borzone, Roberto Ignacio; Rodríguez Poblete, Carolina Elena; Zoroquiain Vélez, José Pablo; Solar González, Antonieta Alejandra; Espino Espino, Alberto Antonio; León Ramírez, Augusto; Fardella B., Carlos; Domínguez Ruiz-Tagle, José Miguel; Astudillo, R.
  • Thumbnail Image
    Item
    Sarcoid-like granulomatous myositis-associated hypercalcemia. An infrequent case to consider
    (2021) Uslar N., Thomas; Olmos Borzone, Roberto Ignacio; Godoy Santín, Jaime; Mellado T., Patricio; González Vicente, Gilberto
    PTH-independent hypercalcemia due to granulomatous disease is well-documented and sarcoidosis is the most characteristic disease, although there are others. We describe a case of sarcoid-like granulomatous myositis. An 87-year-old man was referred with tetraparesis and hypercalcemia (albumin-corrected calcium of 13.4 mg/dl) following a trip to the Caribbean. The evaluation showed a suppressed PTH, 25-hydroxy vitamin D of 7.5 ng/ml, 18F-FDG PET/CT showed markedly increased uptake in intercostal, back, shoulder, buttock and thigh muscles and a deltoid biopsy confirmed extensive granulomatous myositis. He was prescribed glucocorticoids which resulted in normalized plasma calcium levels and complete recovery from tetraparesis. Sarcoid-like granulomatous myositis should be incorporated into the differential diagnosis of PTH-independent hypercalcemia, especially in the absence of clinical features of sarcoidosis and with special emphasis on the use of 18F-FDG PET/CT to ensure a correct approach.
  • Thumbnail Image
    Item
    The aldosterone/renin ratio predicts cardiometabolic disorders in subjects without classic primary aldosteronism
    (2019) Vecchiola Cárdenas, Andrea Paola; Fuentes Zúñiga, Cristóbal Andrés; Barros Lamus, Eric Raúl; Martínez Aguayo, Alejandro Gregorio; García Bruce, Hernán; Allende, Fidel; Solari Gajardo, Sandra; Olmos Borzone, Roberto Ignacio; Carvajal, C.; Tapia-Castillo, A.; Campino Johnson, María del Carmen; Kalergis Parra, Alexis Mikes; Baudrand Biggs, René; Fardella B., Carlos; Vecchiola Cárdenas, Andrea Paola; Fuentes Zúñiga, Cristóbal Andrés; Barros Lamus, Eric Raúl; Martínez Aguayo, Alejandro Gregorio; García Bruce, Hernán; Allende, Fidel; Solari Gajardo, Sandra; Olmos Borzone, Roberto; Carvajal, C.; Tapia-Castillo, A.; Campino Johnson, María del Carmen; Kalergis Parra, Alexis Mikes; Baudrand Biggs, René; Fardella B., Carlos
  • Thumbnail Image
    Item
    ¿Vale la pena utilizar dosis altas de inhibidores de la bomba de protones en la hemorragia péptica aguda?
    (2016) Villalón, Alejandro; Olmos Borzone, Roberto Ignacio; Rada G., Gabriel
  • Thumbnail Image
    Item
    Warthin-like and classic papillary thyroid cancer have similar clinical presentation and prognosis
    (2020) Olmos Borzone, Roberto Ignacio; Muñoz, F.; Donoso Torres, Francisca Andrea; Mosso Gómez, Lorena; Lustig, Nicole; Solar González, Antonieta Alejandra; Droppelmann, Nicolás; Montero, P. H.; Montero Miranda, Pablo Hernán; López, J.; González, H. E.; Domínguez, J. M.; Bruera, M. J.; Ruiz Esquide, M.