Browsing by Author "Nachtigall, Lisa B."

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    Clinical MEN-1 Among a Large Cohort of Patients With Acromegaly
    (2020) Nachtigall, Lisa B.; Guarda, Francisco J.; Lines, Kate E.; Ghajar, Alireza; Dichtel, Laura; Mumbach, Giselle; Zhao, Wenxiu; Zhang, Xun; Tritos, Nicholas A.; Swearingen, Brooke; Miller, Karen K.; Thakker, Rajesh, V
    Context: Clinical multiple endocrine neoplasia type 1 (MEN-1) is diagnosed by the presence of at least 2 MEN-1-associated tumors. Many patients with acromegaly and clinical MEN-1 yield negative testing for MEN1 mutations. While cases of acromegaly and primary hyperparathyroidism (PHP) with negative genetic testing have been reported, its prevalence among patients with acromegaly is undetermined, and the clinical presentation has not been well characterized.
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    Mifepristone Increases Thyroid Hormone Requirements in Patients With Central Hypothyroidism: A Multicenter Study
    (2019) Guarda, Francisco J.; Findling, James; Yuen, Kevin C. J.; Fleseriu, Maria; Nachtigall, Lisa B.
    Purpose: Mifepristone is a glucocorticoid and progesterone receptor blocker that can be used for patients with hyperglycemia and Cushing syndrome in whom surgery failed to achieve remission or who were ineligible for surgery. We report a case series of patients with Cushing disease (CD) and central hypothyroidism that presented with increased levothyroxine requirements during mifepristone therapy.