Browsing by Author "Morales, Eugenia"
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- ItemThe European lactase persistence genotype determines the lactase persistence state and correlates with gastrointestinal symptoms in the Hispanic and Amerindian Chilean population: a case-control and population-based study(BMJ PUBLISHING GROUP, 2011) Morales, Eugenia; Azocar, Lorena; Maul, Ximena; Perez, Claudio; Chianale, Jose; Francisco Miquel, JuanBackground: The lactase persistent (LP) or lactase nonpersistent (LNP) state in European adults is genetically determined by a single nucleotide polymorphism (SNP) located 13.9 kb upstream of the lactase (LCT) gene, known as LCT C>T-13910 (rs4988235). The LNP condition leads to an inability to digest the milk sugar lactose leading to gastrointestinal symptoms and can affect nutrient and calcium intake in certain populations.