Browsing by Author "Morán, S"
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- ItemAdenosine 5′-triphosphate and neuropeptide Y are co-transmitters in conjunction with noradrenaline in the human saphenous vein(1999) Racchi, H; Irarrázabal, MJ; Howard, M; Morán, S; Zalaquett, R; Huidobro-Toro, JP1 Human saphenous veins were used to assess the cooperative participation of adenosine 5-triphosphate (ATP), neuropeptide Y (NPY), and noradrenaline (NA) in the vasomotor responses elicited following electrical depolarization of the perivascular nerve terminals. Rings from recently dissected human biopsies were mounted to record isometric muscular contractions; the motor activity elicited in the circular muscle layer following electrical depolarization (2.5-20 Hz, 50 V, 0.5 msec) were recorded.
- ItemOral rapamycin to prevent human coronary stent restenosis(2004) Guarda, E; Marchant, E; Fajuri, A; Martínez, A; Morán, S; Mendez, M; Uriarte, P; Valenzuela, E; Lazen, RBackground Recent human trials with rapamycin-eluting stents have shown very low restenosis rates. However, the high costs of these devices preclude their use in routine angioplasty, especially when considering multiple stenting. We evaluated whether orally administered rapamycin inhibits in-stent neointimal growth in patients with unstable angina.