Browsing by Author "Mery, Pablo"

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    Chronic Liver Failure and Concomitant Distant Infections Are Associated With High Rates of Neurological Involvement in Pyogenic Spinal Infections
    (LIPPINCOTT WILLIAMS & WILKINS, 2009) Urrutia, Julio; Bono, Christopher M.; Mery, Pablo; Rojas, Claudio; Gana, Natalia; Campos, Mauricio
    Study Design. A retrospective study of a consecutive series of all patients with pyogenic spinal infections treated at a single institution over a 10-year period.
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    Cultured autologous bone marrow stem cells inhibit bony fusion in a rabbit model of posterolateral lumbar fusion with autologous bone graft
    (ELSEVIER SCI LTD, 2010) Urrutia, Julio; Mery, Pablo; Martinez, Rafael; Pizarro, Felipe; Apablaza, Daniel; Mardones, Rodrigo
    Mesenchymal stem cells (MSCs) have been isolated from various tissues and expanded in culture. MSCs add osteogenic potential to ceramic scaffolds when used together. A spinal fusion rabbit model was used to evaluate whether a pellet of cultured, autologous bone marrow MSCs (BMSCs) with osteogenic differentiation could increase the fusion rate when co-grafted with an autologus bone graft compared to autograft alone. Thirty rabbits were randomly assigned to two groups. Group I received bone autograft alone and Group 2 received bone autograft plus a pellet of cultured and differentiated BMSCs. Group 2 rabbits had a bone marrow puncture, after which the BMSC were cultured and osteoblastic differentiation was induced. BMSC cultures were obtained from 12 of 15 rabbits. The 27 rabbits underwent a bilateral, L4-L5 intertransverse fusion with an autograft and in Group 2 rabbits a pellet of differentiated BMSCs was added to the autograft. In Group 1, the fusion rate was 53% (8 of 15 rabbits) and ill Group 2 the fusion rate was 0% (p < 0.05). Adding differentiated BMSCs in a pellet without a scaffold not only failed to increase fusion rate, but completely inhibited bony growth. (C) 2009 Elsevier Ltd. All rights reserved.
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    Early histologic changes following polymethylmethacrylate injection (Vertebroplasty) in rabbit lumbar vertebrae
    (LIPPINCOTT WILLIAMS & WILKINS, 2008) Urrutia, Julio; Bono, Christopher M.; Mery, Pablo; Rojas, Claudio
    Study Design. An ex vivo histologic study in rabbits.
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    Percutaneous Fixation of Posterior Malleolar Fractures: A Contemporary Review
    (2024) Massri-Pugin, Jafet; Morales, Sergio; Serrano, Javier; Mery, Pablo; Filippi, Jorge; Villa, Andrés
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    Role of the CT Scan in Preoperative Planning for Tillaux-Chaput Fractures in Adults
    (2025) Massri Pugin, Jafet Esteban; Matamoro Rueda, Gabriel; Morales, Sergio; Mery, Pablo; Lira, María Jesús; Filippi, Jorge
    Background: Tillaux-Chaput fractures (TCFs) occur in the anterolateral rim of the distal tibia. TCFs are often overlooked on radiographic review, increasing the risk of chronic pain, instability, and ankle osteoarthritis. This study evaluated the effect of the computed tomography (CT) scan on preoperative planning for TCFs in adults.Methods: A retrospective review of ankle fractures evaluated from 2013 to 2023 at a university hospital was conducted. The inclusion criteria were patients ≥18 years of age who underwent radiographic and CT evaluation and had a TCF that was confirmed by CT. The exclusion criteria included pilon and distal tibial fractures and prior ankle surgery. Three orthopaedic surgeons assessed radiographs, classified TCFs using the Rammelt classification, formulated a treatment plan (conservative versus surgical), and, if a surgical treatment was indicated, determined the patient positioning, fixation type, and approach for the TCF. After evaluating CT images, changes in treatment strategy were recorded. Forward stepwise regression was utilized to analyze variables associated with modifications in preoperative planning.Results: A total of 481 fractures had ankle radiographs and CT scans; of these, 83 (17.3%) had a TCF. After the CT evaluation, the Rammelt classification and the surgical decision changed by 69.1% and 12.5%, respectively. Changes in patient positioning, the type of fixation, and the surgical approach for a TCF (when surgery was indicated) occurred in 32.1%, 43.8%, and 35.3% of all cases, respectively. Multivariable analysis showed that the detection of a TCF on CT predicted changes in the surgical decision and fixation type, while changes in the TCF classification predicted modifications in the fixation type and surgical approach. Posterior malleolar fractures were the unique predictor of changes in the patient positioning.Conclusions: CT evaluation modified the surgical decision, type of fixation, and surgical approach for a TCF in 12.5%, 43.8%, and 35.3% of cases, respectively. Moreover, the detection of a TCF and a change in the classification after CT evaluation were predictors of a change in treatment strategy. These findings underscore the importance of the CT scan in the preoperative planning for TCFs in adults. Therefore, we strongly recommend conducting a CT scan when a TCF is suspected in adult patients.Level of Evidence: Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.