Browsing by Author "Mertens, Luc"

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    Clinical Research Regional Vascular Changes and Aortic Dilatation in Pediatric Patients With Bicuspid Aortic Valve
    (2022) Rumman, Rawan K.; Slorach, Cameron; Hui, Wei; Lopez, Carmen; Larios, Guillermo; Fan, Steve; Franco-Cereceda, Anders; Loeys, Bart; Mohamed, Salah A.; Dietz, Harry; Mital, Seema; Andelfinger, Gregor; Mertens, Luc; Grattan, Michael
    Background: Bicuspid aortic valve (BAV) is the most common congenital heart disease, often associated with valve dysfunction, coarctation of the aorta, and ascending aorta dilatation. Aortic dilatation might result from abnormal regional hemodynamics or inherent vascular disease. Vascular function in pediatric BAV remains poorly characterized.
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    Right ventricular function in patients with pulmonary regurgitation with versus without tetralogy of Fallot
    (2019) Larios, Guillermo; Yim, Deane; Dragulescu, Andreea; Mertens, Luc; Grosse-Wortmann, Lars; Friedberg, Mark K.
    Background Right ventricular (RV) dilation from pulmonary valve regurgitation (PR) is common after intervention(s) for pulmonary stenosis (PS) or atresia and intact ventricular septum (PA/IVS). It is not well established whether PR and RV dilation have similar effects on RV function and exercise capacity in these patients compared to patients after repair of tetralogy of Fallot (rToF). The aims of this study were to compare exercise tolerance, RV function and myocardial mechanics in non-ToF versus rToF children with significantly increased and comparable RV volumes.