Browsing by Author "Medina, Pablo"

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    Assessing cohesion and diversity in the collaboration network of the SALURBAL project
    (2023) Baquero, Sofia; Montes, Felipe; Stankov, Ivana; Sarmiento, Olga L.; Medina, Pablo; Slesinski, S. Claire; Diez-Canseco, Francisco; Kroker-Lobos, Maria F.; Teixeira, Waleska; Vives Vergara, Alejandra; Alazraqui, Marcio; Barrientos-Gutierrez, Tonatiuh; Diez Roux, Ana V.; CEDEUS (Chile)
    The SALURBAL (Urban Health in Latin America) Project is an interdisciplinary multinational network aimed at generating and disseminating actionable evidence on the drivers of health in cities of Latin America. We conducted a temporal multilayer network analysis where we measured cohesion over time using network structural properties and assessed diversity within and between different project activities according to participant attributes. Between 2017 and 2020 the SALURBAL network comprised 395 participants across 26 countries, 23 disciplines, and 181 institutions. While the cohesion of the SALURBAL network fluctuated over time, overall, an increase was observed from the first to the last time point of our analysis (clustering coefficient increased [0.83-0.91] and shortest path decreased [1.70-1.68]). SALURBAL also exhibited balanced overall diversity within project activities (0.5-0.6) by designing activities for different purposes such as capacity building, team-building, research, and dissemination. The network's growth was facilitated by the creation of new diverse collaborations across a range of activities over time, while maintaining the diversity of existing collaborations (0.69-0.75 between activity diversity depending on the attribute). The SALURBAL experience can serve as an example for multinational research projects aiming to build cohesive networks while leveraging heterogeneity in countries, disciplines, career stage, and across sectors.
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    Effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) in Treating Borderline Personality Disorder: A Randomized Controlled Trial
    (2025) Nvo Fernandez, Marcelo; Salas, Fabiola; Miño Reyes, Valentina; Ahumada Méndez, Francisco; Medina, Pablo; Avello Saez, Daniela Margot; Floriano Landim, Síbila; Via, Marc; Napolitano, Nicholas; Leiva-Bianchi, Marcelo
    Background:Eye movement desensitization and reprocessing (EMDR) is recommended by major health organizations for trauma treatment, but its efficacy for borderline personality disorder (BPD) remains unestablished. This study aims to evaluate EMDR’s effectiveness in treating BPD through a randomized controlled trial (RCT) and compare its outcomes with cognitive behavioral therapy (CBT).Methods:A total of 76 individuals participated in the RCT, with 18 patients (78% female) completing the study. Participants were randomly assigned to receive either EMDR (n = 8) or CBT (n = 10) via teletherapy sessions. Trauma symptoms were assessed using the international trauma questionnaire (ITQ), BPD symptoms were assessed using the Personality Assessment Inventory-Borderline Features Scale (PAI-BOR), and post-traumatic growth (PTG) was assessed using the post-traumatic growth inventory (PTGI). Additionally, attentional evaluations were conducted at behavioral and electroencephalographic levels through an oddball paradigm. A final comparison was made between a participant who did not complete the therapeutic process and a participant who did.Results:Both EMDR and CBT treatments significantly improved trauma and BPD symptoms, as well as post-traumatic growth. The effect size was moderate for ITQ (η2 = 0.615) and PTGI (η2 = 0.610), and low for PAI-BOR (η2 = 0.147). Symptomatic participants showed a decrease in ITQ (p = 0.006) and PAI-BOR (p = 0.047) scores, and an increase in PTGI scores (p = 0.028).Conclusions:Both EMDR and CBT significantly improved trauma and BPD symptoms, as well as post-traumatic growth. Additionally, EMDR showed benefits in response accuracy and speed, with a correct response rate of 97% when comparing two participants (with and without therapy). However, completely clean electroencephalography (EEG) data were not obtained from both participants for a deeper comparison.Clinical Trial Registration:The study was registered at https://doi.org/10.1186/ISRCTN91146045, registration number: ISRCTN91146045, registration date: 21 May 2021.
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    The Stochastic Transport Dynamics of a Conserved Quantity on a Complex Network
    (2018) Medina, Pablo ; Clark, Jaime; Kiwi, Miguel ; Torres, Felipe ; Rogan, José; Valdivia, Juan Alejandro