Browsing by Author "McAllister, F."

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Microbial Regulation of Vitamin D Linked to Colorectal Cancer: A Sex Bias
    (2023) Riquelme Sánchez, Erick Marcelo; Howell, R.M.; McAllister, F.
    In a recent issue of Cancer Cell, Li and colleagues revealed that Carnobacterium maltaromaticum (C. maltaromaticum) was significantly depleted in the stool samples of patients with colorectal cancer in a female-specific manner. C. maltaromaticum actively participated in the generation of vitamin D intermediary metabolites, which together with Faecalibacterium prausnitzii and Lachnispiraceae bacterium produce an active metabolite of vitamin D that protects against colorectal cancer development. C. maltaromaticum supplementation induced in a female-specific manner an increase in vitamin D levels that would activate its receptor in the colonic epithelium, protecting against the development of colorectal cancer.