Browsing by Author "Matsuoka, Shin"

Now showing 1 - 4 of 4
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    Airway Count and Emphysema Assessed by Chest CT Imaging Predicts Clinical Outcome in Smokers
    (ELSEVIER, 2010) Diaz, Alejandro A.; Valim, Clarissa; Yamashiro, Tsuneo; San Jose Estepar, Raul; Ross, James C.; Matsuoka, Shin; Bartholmai, Brian; Hatabu, Hiroto; Silverman, Edwin K.; Washko, George R.
    Background: Recently, it has been shown that emphysematous destruction of the lung is associated with a decrease in the total number of terminal bronchioles. It is unknown whether a similar decrease is visible in the more proximal airways. We aimed to assess the relationships between proximal airway count, CT imaging measures of emphysema, and clinical prognostic factors in smokers, and to determine whether airway count predicts the BMI, airflow obstruction, dyspnea, and exercise capacity (BODE) index.
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    Collapsibility of Lung Volume by Paired Inspiratiory and Expiratory CT Scans: Correlations with Lung Function and Mean Lung Density
    (ELSEVIER SCIENCE INC, 2010) Yamashiro, Tsuneo; Matsuoka, Shin; Bartholmai, Brian J.; Estepar, Raul San Jose; Ross, James C.; Diaz, Alejandro; Murayama, Sadayuki; Silverman, Edwin K.; Hatabu, Hiroto; Washko, George R.
    Rationale and Objectives: To evaluate the relationship between measurements of lung volume (LV) on inspiratory/expiratory computed tomography (CT) scans, pulmonary function tests (PFT), and CT measurements of emphysema in individuals with chronic obstructive pulmonary disease.
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    Quantitative CT Measurement of Cross-sectional Area of Small Pulmonary Vessel in COPD: Correlations with Emphysema and Airflow Limitation
    (ELSEVIER SCIENCE INC, 2010) Matsuoka, Shin; Washko, George R.; Dransfield, Mark T.; Yamashiro, Tsuneo; Estepar, Raul San Jose; Diaz, Alejandro; Silverman, Edwin K.; Patz, Samuel; Hatabu, Hiroto
    Rationale and Objectives: Pulmonary vascular alteration is one of the characteristic features of chronic obstructive pulmonary disease (COPD). Recent studies suggest that vascular alteration is closely related to endothelial dysfunction and may be further influenced by emphysema. However, the relationship between morphological alteration of small pulmonary vessels and the extent of emphysema has not been assessed in vivo. The objectives of this study are: to evaluate the correlation of total cross-sectional area (CSA) of small pulmonary vessels with the extent of emphysema and airflow obstruction using CT scans and to assess the difference of total CSA between COPD phenotypes.
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    Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD
    (W B SAUNDERS CO LTD, 2010) Diaz, Alejandro A.; Bartholmai, Brian; Estepar, Raul San Jose; Ross, James; Matsuoka, Shin; Yamashiro, Tsuneo; Hatabu, Hiroto; Reilly, John J.; Silverman, Edwin K.; Washko, George R.
    Objective: To assess the association of emphysema and airway disease assessed by volumetric computed tomography (CT) with exercise capacity in subjects with chronic obstructive pulmonary disease (COPD).