Browsing by Author "MOORE, GD"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    EFFECTS OF DELAYED TRANSFER AND TREATMENT WITH ESTROGEN ON THE TRANSPORT OF MICROSPHERES BY THE RAT OVIDUCT
    (1988) MOORE, GD; CROXATTO, HB
    Starch or dextran blue microspheres were transferred microsurgically to the influndibulum of the oviduct on Days 1, 2, or 3 of pregnancy of control and oestradiol-treated rats. The animals were killed a few hours to several days after transfer to assess the number and distribution of ova and microspheres in the tract. After transfer on Day 1 of pregnancy, microspheres and eggs crossed the ampullary-isthmic junction (AIJ) 18 h after ovulation. After transfer on Day 2 of pregnancy, more than 50% of microspheres were retained in the ampulla, indicating that the AIJ changes again 34 h after ovulation. Treatment with oestradiol did not advance the passage of eggs or microspheres across the AIJ but caused accelerated transport through the isthmus as soon as the eggs or microspheres reached this segment. Dextran blue microspheres were seen to move back and forth in the isthmus of control anaesthetized rats at a frequency of 5-6 times/min. Between 7 and 20 h after treatment with oestradiol the frequency of these movements was significantly augmented, indicating that increased frequency of contractions of the smooth muscle of the isthmus precedes and accompanies accelerated transport of ova through this segment.