Browsing by Author "MIQUEL, JF"

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    ISOLATION AND PURIFICATION OF HUMAN BILIARY VESICLES WITH POTENT CHOLESTEROL-NUCLEATION-PROMOTING ACTIVITY
    (1992) MIQUEL, JF; RIGOTTI, A; ROJAS, E; BRANDAN, E; NERVI, F
    1. Cholesterol nucleation is a critical step in the formation of cholesterol gallstones. This nucleation takes place after aggregation and fusion of cholesterol-rich biliary vesicles, a process probably modulated by biliary proteins. The present study was conducted to identify specific proteins associated with native cholesterol-rich biliary vesicles and to explore their effect on the cholesterol-nucleation time of supersaturated artificial bile.