Browsing by Author "Lustig, Nicole"
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- ItemEndocarditis infecciosa por Listeria monocytogenes: revisión de la literatura a partir de un caso clínico(2013) Marin, Arnaldo; Lustig, Nicole; Cruz Urrutia, Ricardo Javier; Cordova, SamuelInfective endocarditis caused by Listeria monocytogenes is an extremely rare but usually aggressive disease. We have seen in recent years an increase in age of onset of this disease and a predilection for patients With valvular disease, especially prosthetic valve. The treatment of choice is ampicillin, which is combined with gentamicin for synergy. It is known that even with treatment the Mortality is very high and higher than in other types of bacterial endocarditis. With optimal therapy, that is medical-surgical, mortality has declined significantly in recent years. We presents a review of literature and a clinical ease of a patient with a febrile syndrome diagnosed as a infective endocarditis caused by L. monocytogenes treated Medically with successful Outcome to date.
- Item¿Es efectivo el iloprost en el fenómeno de Raynaud secundario?(2015) Lustig, Nicole; Rada G., Gabriel
- ItemEvaluación para el aprendizaje : experiencia en un curso teórico de pregrado en medicina(2015) Pérez, Gonzalo; Kattan Tala, Eduardo José; Collins, Luz; Wright Navarrete, Ana Cecilia; Rybertt, Tomás; González, Agustín; Sirhan Nahum, Marisol; Solís, Nancy; Pizarro Rojas, Margarita Alicia; Arrese Jiménez, Marco; Sarfatis Feige, Alberto; Lustig, Nicole; Arab Verdugo, Juan Pablo; Labarca L., Jaime; Riquelme Pérez, Arnoldo
- ItemManagement of Helicobacter pylori infection in Latin America : A Delphi technique-based consensus(2014) Rollan, Antonio; Arab Verdugo, Juan Pablo; Camargo, M. Constanza; Candia Balboa, Roberto; Harris D., Paul R.; Ferreccio Readi, Catterina; Rabkin, Charles S.; Gana Ansaldo, Juan Cristóbal; Cortés, Pablo; Herrero, Rolando; Durán, Luisa; García, Apolinaria; Toledo, Claudio; Espino Espino, Alberto Antonio; Lustig, Nicole; Sarfatis Feige, Alberto; Figueroa, Catalina; Torres, Javier; Riquelme Pérez, Arnoldo
- ItemPericarditis constrictiva como presentación grave e infrecuente de lupus eritematoso sistémico : reporte de un caso y revisión de la literatura(2014) Lustig, Nicole; Florenzano Valdés, Pablo Felipe; Sanhueza, L.; Cid, X.; Ramos, G.; Thone, Natalie; Fullerton, D.
- ItemSalud ósea en pacientes sometidos a trasplante de precursores hematopoyéticos: un nuevo problema a considerar(2016) Florenzano Valdés, Pablo Felipe; Ernst Diaz, Daniel Matias; Lustig, Nicole; Rojas, Patricio; Ramírez, Pablo; Campusano Montaño, Claudia
- ItemTeaching therapy decision-making to medical students. A prospective mixed-methods evaluation of a curricular innovation(2024) García-Huidobro Munita, Diego Nicolás; Fernandez, Joaquín; Espinosa, Pilar; Lustig, Nicole; Perez, Ignacio; Letelier Saavedra, Luz MaríaTherapy decision-making (TDM) is an essential medical skill. However, teaching therapeutic reasoning poses significant challenges. We present a comprehensive TDM course for medical students and report on student satisfaction with the educational strategies, their perceived importance of various TDM domains, and their self-efficacy in incorporating these elements into clinical decisions. Methods Three student cohorts participated in a 16-week TDM course, which included self-instruction modules, application assignments, faculty symposia, and application seminars as educational strategies. The course focused on TDM and emphasized how factors such as the patient’s diagnosis, needs and preferences, treatment options, physicians’ viewpoints, the patient-physician relationship, and contexts of medical practice impact TDM. After the course, students completed a before-and-after survey assessing their satisfaction with the educational strategies, their perceived importance of ten TDM domains, and their ability to incorporate these domains into patient management. Scores ranged from 1 to 10. Students from the first two cohorts completed a 1- and 2-year follow-ups. Results A total of 387 students completed the course. All educational strategies were well-received, with self-instruction modules and faculty symposia yielding the highest satisfaction rates (94.8% and 88.6% respectively). Before-and-after evaluations indicated that students` perceived importance of the TDM domains increased from an average of 8.0 ± 2.4 at baseline to 9.9 ± 1.0 after the course. Additionally, their perceived ability to integrate TDM domains into practice rose from an average of 5.2 ± 3.2 to 9.4 ± 1.5 by the end of the course. Follow-up results showed a decrease in these outcomes over time. Conclusion This course serves as a successful model for systematically teaching TDM to medical students.
- ItemThyroid-Stimulating Hormone Reference Ranges in the First Trimester of Pregnancy in an Iodine-Sufficient Country(2018) Castillo, C.; Lustig, Nicole; Margozzini Maira, Paula; Gómez, A.; Rojas Villar, María Paulina; Muzzo, S.; Mosso Gómez, Lorena
- ItemTwo Decades of Thyroid Nodule Cytology in Children: Malignancy Risk Assessment at a Tertiary Care Center(2024) Pino, Consuelo; Dominguez, Jose Miguel; Solar, Antonieta; Zoroquiain, Pablo; Cruz, Francisco; Garcia, Cristian; De Barbieri, Florencia; Mosso, Lorena; Lustig, Nicole; Gonzalez, Hernan; Leon, Augusto; Goni, Ignacio; Contreras, Andy; Grob, FranciscaIntroduction: Pediatric thyroid nodules exhibit higher malignancy rates compared to adults and are associated with increased incidences of metastases and recurrences. The American Thyroid Association recommends surgery for indeterminate thyroid biopsies in children based on these higher malignancy risks, though this approach may lead to overtreatment. However, there remains a lack of comprehensive pediatric data to inform clinical decisions. This study examines the risk of malignancy (ROM) in pediatric thyroid nodules using the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) and assesses the diagnostic accuracy of fine-needle aspiration (FNA) biopsy compared to histological outcomes. Methods: A retrospective cross-sectional analysis was performed on patients under 19 years with thyroid nodules who underwent FNA and thyroidectomy at a tertiary care center. The sensitivity, specificity, positive predictive value, negative predictive value, and ROM of cytological biopsies were evaluated using TBSRTC criteria, with histology serving as the gold standard. Two analyses were conducted to assess diagnostic accuracy: (a) TBSRTC II as negative and TBSRTC VI as positive and (b) TBSRTC II as negative with TBSRTC V and VI as positive. For neoplasia detection, TBSRTC II was deemed negative, while TBSRTC IV, V, and VI were considered positive. TBSRTC categories III and I were excluded from the performance analysis and evaluated separately. Follicular neoplasm or lesions suspicious for follicular neoplasm (FN/SFN) were treated as positive outcomes, correlated with the presence of adenoma or carcinoma in the surgical specimen. Results: Of 75 nodules from 73 patients, 28 (37.3%) were benign and 47 (62.6%) malignant. No significant differences in gender or age were noted between groups. The ROM in each TBSRTC was Bethesda I 0/2, 0%; II 0/13, 0%; III 2/7, 29%: IV 6/14, 43%; V 10/10, 100%, and VI 29/29, 100%. A sensitivity of 78.38% and specificity of 100% for FNA in detecting malignancy was found, with an even higher sensitivity (100%) for detecting neoplasia in TBSRTC IV. Conclusions: This study reveals that indeterminate thyroid nodules in pediatric patients exhibit a higher rate of malignancy compared to adults, yet align with rates previously reported in the pediatric population. These findings highlight the critical need for guidelines tailored specifically to the management of thyroid nodules and thyroid cancer in children.
- ItemWarthin-like and classic papillary thyroid cancer have similar clinical presentation and prognosis(2020) Olmos Borzone, Roberto Ignacio; Muñoz, F.; Donoso Torres, Francisca Andrea; Mosso Gómez, Lorena; Lustig, Nicole; Solar González, Antonieta Alejandra; Droppelmann, Nicolás; Montero, P. H.; Montero Miranda, Pablo Hernán; López, J.; González, H. E.; Domínguez, J. M.; Bruera, M. J.; Ruiz Esquide, M.