Browsing by Author "Liopyris, K."
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- ItemAssociation of Multiple Aggregated Yellow-White Globules With Nonpigmented Basal Cell Carcinoma(2020) Navarrete Dechent, Cristián Patricio; Liopyris, K.; Rishpon, A.; Marghoob, N. G.; Cordova, M.; Dusza, S. W.; Sahu, A.; Kose, K.; Oliviero, M.; Rabinovitz, H.; Busam, K. J.; Marchetti, M. A.; Chen, C. C. J.; Marghoob, A. A.
- ItemHuman surface anatomy terminology for dermatology: a Delphi consensus from the International Skin Imaging Collaboration(2020) Navarrete-Dechent, C.; Liopyris, K.; Molenda, M. A.; Braun, R.; Curiel-Lewandrowski, C.; Dusza, S. W.; Guitera, P.; Hofmann-Wellenhof, R.; Kittler, H.; Lallas, A.; Malvehy, J.; Marchetti, M. A.; Oliviero, M.; Pellacani, G.; Puig, S.; Soyer, H. P.; Tejasvi, T.; Thomas, L.; Tschandl, P.; Scope, A.; Marghoob, A. A.; Halpern, A. C.Background There is no internationally vetted set of anatomic terms to describe human surface anatomy. Objective To establish expert consensus on a standardized set of terms that describe clinically relevant human surface anatomy. Methods We conducted a Delphi consensus on surface anatomy terminology between July 2017 and July 2019. The initial survey included 385 anatomic terms, organized in seven levels of hierarchy. If agreement exceeded the 75% established threshold, the term was considered 'accepted' and included in the final list. Terms added by the participants were passed on to the next round of consensus. Terms with <75% agreement were included in subsequent surveys along with alternative terms proposed by participants until agreement was reached on all terms. Results The Delphi included 21 participants. We found consensus (>= 75% agreement) on 361/385 (93.8%) terms and eliminated one term in the first round. Of 49 new terms suggested by participants, 45 were added via consensus. To adjust for a recently published International Classification of Diseases-Surface Topography list of terms, a third survey including 111 discrepant terms was sent to participants. Finally, a total of 513 terms reached agreement via the Delphi method. Conclusions We have established a set of 513 clinically relevant terms for denoting human surface anatomy, towards the use of standardized terminology in dermatologic documentation.
- ItemIncompletely excised lentigo maligna melanoma is associated with unpredictable residual disease: clinical features and the emerging role of reflectance confocal microscopy(2020) Navarrete-Dechent, C.; Aleissa, S.; Cordova, M.; Liopyris, K.; Lee, E. H.; Rossi, A. M.; Hollman, T.; Pulitzer, M.; Lezcano, C.; Busam, K. J.; Marghoob, A. A.; Chen, C-C J.; Nehal, K. S.Background Lentigo maligna/lentigo maligna melanoma (LM/LMM) poses a treatment and surgical challenge given unpredictable subclinical extension resulting in incomplete excision. Objectives To describe the demographic, clinical and pathologic characteristics of incompletely excisedLM/LMM. To evaluate the potential role of reflectance confocal microscopy (RCM). Patients and methods A retrospective review of a melanoma database at a tertiary cancer centre for patients referred with 'incompletely excisedLM/LMM' or 'incompletely excised melanoma' between October 2006 and July 2017. We recorded clinical and pathological data and surgical margins needed to clear the residualLM/LMM. The second part consisted of a prospective cohort of patients in whichRCMwas performed when presenting with incompletely excisedLM/LMM. Results We included a total of 67 patients (retrospective + prospective cohort); mean age was 64.9 (standard deviation: 11.3) years and 52.2% were males. For the retrospective cohort (n = 53), the mean scar size was 3.4 cm. The average initial margins excised prior to presentation were 4.8 mm (range 3-7 mm). The average additional margin needed to clear the residual, incompletely excisedLM/LMMwas 7.8 mm. For the prospective cohort (n = 14), there were no differences in age, gender or size when compared to the retrospective cohort.RCMhad a diagnostic accuracy of 78.6%, a sensitivity of 90.9%, a specificity of 33.3% and a positive predictive value of 83.3% for the detection of incompletely excisedLM/LMM. Conclusions Incompletely excisedLM/LMMis a poorly characterized clinical-pathological scenario that may require considerable extra margins for microscopic clearance.RCMmay emerge as a valuable tool for the evaluation of patients with incompletely excisedLM/LMM.
- Item‘Inverse association between the total naevus count and melanoma thickness’(2020) Marghoob, N. G.; Liopyris, K.; Navarrete Dechent, Cristián Patricio; Dusza, S. W.; Balais, G.; Megaris, A.; Papageorgiou, C.; Apalla, Z.; Lallas, A.
- ItemManagement of complex head-and-neck basal cell carcinomas using a combined reflectance confocal microscopy/optical coherence tomography : a descriptive study(2020) Navarrete Dechent, Cristián Patricio; Aleissa, S.; Cordova, M.; Liopyris, K.; Sahu, A.; Rossi, A. M.; Lee, E. H.; Nehal, K. S.
- ItemMulticlass Artificial Intelligence in Dermatology : Progress but Still Room for Improvement(2020) Navarrete Dechent, Cristián Patricio; Liopyris, K.; Marchetti, M. A.
- ItemOptical imaging guided- ‘precision’ biopsy of skin tumors : a novel approach for targeted sampling and histopathologic correlation(2020) Navarrete Dechent, Cristián Patricio; Cordova, M.; Sahu, A.; Liopyris, K.; Rishpon, A.; Chen, C.; Rajadhyaksha, M.; Busam, K. J.; Marghoob, A. A.; Chen, C. S. J.
- ItemPerformance of a deep neural network in teledermatology: a single-centre prospective diagnostic study(2021) Munoz-Lopez, C.; Ramirez-Cornejo, C.; Marchetti, M. A.; Han, S. S.; Del Barrio-Diaz, P.; Jaque, A.; Uribe, P.; Majerson, D.; Curi, M.; Del Puerto, C.; Reyes-Baraona, F.; Meza-Romero, R.; Parra-Cares, J.; Araneda-Ortega, P.; Guzman, M.; Millan-Apablaza, R.; Nunez-Mora, M.; Liopyris, K.; Vera-Kellet, C.; Navarrete-Dechent, C.Background The use of artificial intelligence (AI) algorithms for the diagnosis of skin diseases has shown promise in experimental settings but has not been yet tested in real-life conditions.
- ItemReflectance confocal microscopy and dermoscopy aid in evaluating repigmentation within or adjacent to lentigo maligna melanoma surgical scars(2020) Navarrete Dechent, Cristián Patricio; Cordova, M.; Liopyris, K.; Rishpon, A.; Aleissa, S.; Rossi, A.M.; Lee, E.; Chen, C.C.J.; Busam, K.J.; Marghoob, A.A.; Nehal, K.S.
- ItemReflectance confocal microscopy confirms residual basal cell carcinoma on clinically negative biopsy sites before Mohs micrographic surgery : a prospective study(2019) Navarrete Dechent, Cristián Patricio; Córdova, M.; Aleissa, S.; Liopyris, K.; Dusza, S. W.; Phillips, W.; Rossi, A. M.; Lee, E. H.; Marghoob, A. A.; Nehal, K. S.
- ItemReflectance confocal microscopy-guided carbon dioxide laser ablation of low-risk basal cell carcinomas : a prospective study(2019) Navarrete Dechent, Cristián Patricio; Córdova, M.; Liopyris, K.; Yelamos, O.; Aleissa, S.; Hibler, B.; Sierra, H.; Sahu, A.; Blank, N.; Rajadhyaksha, M.; Rossi, A.