Browsing by Author "Li, Shuo"

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    JUNO sensitivity to invisible decay modes of neutrons
    (Springer Nature, 2025) Abusleme Hoffman, Ángel Christian; Adam, Thomas; Adamowicz, Kai; Ahmad, Shakeel; Ahmed, Rizwan; Aiello, Sebastiano; Campeny, Agustín; Jeria Pérez, Ignacio Francisco; Ochoa-Ricoux, Juan Pedro; Walker Galdames, Pablo; Antonelli, Vito; Antoshkina, Tatiana; de André, João P. A. M.; Auguste, Didier; Bai, Weidong; Balashov, Nikita; Baldini, Wander; Barresi, Andrea; Basilico, Davide; Baussan, Eric; Bellato, Marco; Beretta, Marco; Bergnoli, Antonio; Bick, Daniel; Bieger, Lukas; Biktemerova, Svetlana; Birkenfeld, Thilo; Blake, Iwan; Blyth, Simon; Bolshakova, Anastasia; Bongrand, Mathieu; Breton, Dominique; Brigatti, Augusto; Brugnera, Riccardo; Bruno, Riccardo; Budano, Antonio; Busto, Jose; Cabrera, Anatael; Caccianiga, Barbara; Cai, Hao; Cai, Xiao; Cai, Yanke; Cai, Zhiyan; Callier, Stéphane; Calvez, Steven; Cammi, Antonio; An, Fengpeng; Cao, Chuanya; Cao, Guofu; Cao, Jun; Caruso, Rossella; Cerna, Cédric; Cerrone, Vanessa; Chang, Jinfan; Chang, Yun; Chatrabhuti, Auttakit; Chen, Chao; Chen, Guoming; Chen, Pingping; Chen, Shaomin; Chen, Xin; Chen, Yiming; Chen, Yixue; Chen, Yu; Chen, Zelin; Chen, Zhangming; Chen, Zhiyuan; Chen, Zikang; Cheng, Jie; Cheng, Yaping; Cheng, Yu C.; Chepurnov, Alexander; Chetverikov, Alexey; Chiesa, Davide; Chimenti, Pietro; Chin, Yen-Ting; Chou, Po-Lin; Chu, Ziliang; Chukanov, Artem; Claverie, Gérard; Clementi, Catia; Clerbaux, Barbara; Molla, Marta C.; Lorenzo, Selma C. D.; Coppi, Alberto; Corti, Daniele; Csakli, Simon; Cui, Chenyang; Corso, Flavio D.; Dalager, Olivia; Datta, Jaydeep; De La Taille, Christophe; Deng, Zhi; Deng, Ziyan; Ding, Xiaoyu; Ding, Xuefeng; Ding, Yayun; Dirgantara, Bayu; Dittrich, Carsten; Dmitrievsky, Sergey; Dohnal, Tadeas; Dolzhikov, Dmitry; Donchenko, Georgy; Dong, Jianmeng; Doroshkevich, Evgeny; Dou, Wei; Dracos, Marcos; Druillole, Frédéric; Du, Ran; Du, Shuxian; Duan, Yujie; Dugas, Katherine; Dusini, Stefano; Duyang, Hongyue; Eck, Jessica; Enqvist, Timo; Fabbri, Andrea; Fahrendholz, Ulrike; Fan, Lei; Fang, Jian; Fang, Wenxing; Fedoseev, Dmitry; Feng, Li-Cheng; Feng, Qichun; Ferraro, Federico; Fournier, Amélie; Fritsch, Fritsch; Gan, Haonan; Gao, Feng; Gao, Feng; Garfagnini, Alberto; Gavrikov, Arsenii; Giammarchi, Marco; Giudice, Nunzio; Gonchar, Maxim; Gong, Guanghua; Gong, Hui; Gornushkin, Yuri; Grassi, Marco; Gromov, Maxim; Gromov, Vasily; Gu, Minghao; Gu, Xiaofei; Gu, Yu; Guan, Mengyun; Guan, Yuduo; Guardone, Nunzio; Guizzetti, Rosa M.; Guo, Cong; Guo, Wanlei; Hagner, Caren; Han, Hechong; Han, Ran; Han, Yang; He, Jinhong; He, Miao; He, Wei; He, Xinhai; Heinz, Tobias; Hellmuth, Patrick; Heng, Yuekun; Herrera, Rafael; Hor, YuenKeung; Hou, Shaojing; Hsiung, Yee; Hu, Bei-Zhen; Hu, Hang; Hu, Jun; Hu, Peng; Hu, Shouyang; Hu, Tao; Hu, Yuxiang; Hu, Zhuojun; Huang, Guihong; Huang, Hanxiong; Huang, Jinhao; Huang, Junting; Huang, Kaixuan; Huang, Shengheng; Huang, Wenhao; Huang, Xin; Huang, Xingtao; Huang, Yongbo; Hui, Jiaqi; Huo, Lei; Huo, Wenju; Huss, Cédric; Hussain, Safeer; Imbert, Leonard; Ioannisian, Ara; Isocrate, Roberto; Jafar, Arshak; Jelmini, Beatrice; An, Qi; Ji, Xiaolu; Jia, Huihui; Jia, Junji; Jian, Siyu; Jiang, Cailian; Jiang, Di; Jiang, Guangzheng; Jiang, Wei; Jiang, Xiaoshan; Jiang, Xiaozhao; Jiang, Yixuan; Jing, Xiaoping; Jollet, Cécile; Kang, Li; Karaparabil, Rebin; Kazarian, Narine; Khan, Ali; Khatun, Amina; Khosonthongkee, Khanchai; Korablev, Denis; Kouzakov, Konstantin; Krasnoperov, Alexey; Kuleshov, Sergey; Kumaran, Sindhujha; Kutovskiy, Nikolay; Labit, Loïc; Lachenmaier, Tobias; Lai, Haojing; Landini, Cecilia; Leblanc, Sébastien; Lefevre, Frederic; Lei, Ruiting; Leitner, Rupert; Leung, Jason; Li, Demin; Li, Fei; Li, Fule; Li, Gaosong; Li, Hongjian; Li, Huang; Li, Jiajun; Li, Min; Li, Nan; Li, Qingjiang; Li, Ruhui; Li, Rui; Li, Shanfeng; Li, Shuo; Li, Tao; Li, Teng; Li, Weidong; Li, Weiguo; Li, Xiaomei; Li, Xiaonan; Li, Xinglong; Li, Yi; Li, Yichen; Li, Yufeng; Li, Zhaohan; Li, Zhibing; Li, Ziyuan; Li, Zonghai; Liang, An-An; Liang, Hao; Liang, Hao; Liao, Jiajun; Liao, Yilin; Liao, Yuzhong; Limphirat, Ayut; Lin, Guey-Lin; Lin, Shengxin; Lin, Tao; Ling, Jiajie; Ling, Xin; Lippi, Ivano; Liu, Caimei; Liu, Fang; Liu, Fengcheng; Liu, Haidong; Liu, Haotian; Liu, Hongbang; Liu, Hongjuan; Liu, Hongtao; Liu, Hongyang; Liu, Jianglai; Liu, Jiaxi; Liu, Jinchang; Liu, Min; Liu, Qian; Liu, Qin; Liu, Runxuan; Liu, Shenghui; Liu, Shubin; Liu, Shulin; Liu, Xiaowei; Liu, Xiwen; Liu, Xuewei; Liu, Yankai; Liu, Zhen; Loi, Lorenzo; Lokhov, Alexey; Lombardi, Paolo; Lombardo, Claudio; Loo, Kai; Lu, Chuan; Lu, Haoqi; Lu, Jingbin; Lu, Junguang; Lu, Meishu; Lu, Peizhi; Lu, Shuxiang; Lu, Xianguo; Lubsandorzhiev, Bayarto; Lubsandorzhiev, Sultim; Ludhova, Livia; Lukanov, Arslan; Luo, Fengjiao; Luo, Guang; Luo, Jianyi; Luo, Shu; Luo, Wuming; Luo, Xiaojie; Lyashuk, Vladimir; Ma, Bangzheng; Ma, Bing; Ma, Qiumei; Ma, Si; Ma, Xiaoyan; Ma, Xubo; Maalmi, Jihane; Mai, Jingyu; Malabarba, Marco; Malyshkin, Yury; Mandujano, Roberto C.; Mantovani, Fabio; Mao, Xin; Mao, Yajun; Mari, Stefano M.; Marini, Filippo; Martini, Agnese; Mayer, Matthias; Mayilyan, Davit; Mednieks, Ints; Meng, Yue; Meraviglia, Anita; Meregaglia, Anselmo; Meroni, Emanuela; Miramonti, Lino; Mohan, Nikhil; Montuschi, Michele; Reveco, Cristobal M.; Nastasi, Massimiliano; Naumov, Dmitry V.; Naumova, Elena; Navas-Nicolas, Diana; Nemchenok, Igor; Thi, Minh T. N.; Nikolaev, Alexey; Ning, Feipeng; Ning, Zhe; Nunokawa, Hiroshi; Oberauer, Lothar; Andronico, Giuseppe; Olshevskiy, Alexander; Orestano, Domizia; Ortica, Fausto; Othegraven, Rainer; Paoloni, Alessandro; Parker, George; Parmeggiano, Sergio; Patsias, Achilleas; Pei, Yatian; Pelicci, Luca; Peng, Anguo; Peng, Haiping; Peng, Yu; Peng, Zhaoyuan; Percalli, Elisa; Perrin, Willy; Perrot, Frédéric; Petitjean, Pierre-Alexandre; Petrucci, Fabrizio; Pilarczyk, Oliver; Rico, Luis F. P.; Popov, Artyom; Poussot, Pascal; Previtali, Ezio; Qi, Fazhi; Qi, Ming; Qi, Xiaohui; Qian, Sen; Qian, Xiaohui; Qian, Zhen; Qiao, Hao; Qin, Zhonghua; Qiu, Shoukang; Qu, Manhao; Qu, Zhenning; Ranucci, Gioacchino; Re, Alessandra; Rebii, Abdel; Redchuk, Mariia; Reina, Gioele; Ren, Bin; Ren, Jie; Ren, Yuhan; Ricci, Barbara; Rientong, Komkrit; Rifai, Mariam; Roche, Mathieu; Rodphai, Narongkiat; Romani, Aldo; Roskovec, Bedřich; Ruan, Xichao; Rybnikov, Arseniy; Sadovsky, Andrey; Saggese, Paolo; Sandanayake, Deshan; Sangka, Anut; Sava, Giuseppe; Sawangwit, Utane; Schever, Michaela; Schwab, Cédric; Schweizer, Konstantin; Selyunin, Alexandr; Serafini, Andrea; Settimo, Mariangela; Shao, Junyu; Sharov, Vladislav; Shi, Hexi; Shi, Jingyan; Shi, Yanan; Shutov, Vitaly; Sidorenkov, Andrey; Šimkovic, Fedor; Singhal, Apeksha; Sirignano, Chiara; Siripak, Jaruchit; Sisti, Monica; Smirnov, Mikhail; Smirnov, Oleg; Sokolov, Sergey; Songwadhana, Julanan; Soonthornthum, Boonrucksar; Sotnikov, Albert; Sreethawong, Warintorn; Stahl, Achim; Stanco, Luca; Stankevich, Konstantin; Steiger, Hans; Steinmann, Jochen; Sterr, Tobias; Stock, Matthias R.; Strati, Virginia; Strizh, Michail; Studenikin, Alexander; Su, Aoqi; Su, Jun; Su, Jun; Sun, Guangbao; Sun, Shifeng; Sun, Xilei; Sun, Yongjie; Sun, Yongzhao; Sun, Zhengyang; Suwonjandee, Narumon; Takenaka, Akira; Tan, Xiaohan; Tang, Jian; Tang, Jingzhe; Tang, Qiang; Tang, Quan; Tang, Xiao; Hariharan, Vidhya T.; Tkachev, Igor; Tmej, Tomas; Torri, Marco D. C.; Triossi, Andrea; Trzaska, Wladyslaw; Tung, Yu-Chen; Tuve, Cristina; Ushakov, Nikita; Vedin, Vadim; Venettacci, Carlo; Verde, Giuseppe; Vialkov, Maxim; Viaud, Benoit; Vollbrecht, Cornelius M.; Sturm, Katharina v.; Vorobel, Vit; Voronin, Dmitriy; Votano, Lucia; Anfimov, Nikolay; Wang, Caishen; Wang, Chung-Hsiang; Wang, En; Wang, Guoli; Wang, Hanwen; Wang, Jian; Wang, Jun; Wang, Li; Wang, Lu; Wang, Meng; Wang, Meng; Wang, Mingyuan; Wang, Qianchuan; Wang, Ruiguang; Wang, Sibo; Wang, Siguang; Wang, Wei; Wang, Wenshuai; Wang, Xi; Wang, Xiangyue; Wang, Yangfu; Wang, Yaoguang; Wang, Yi; Wang, Yi; Wang, Yifang; Wang, Yuanqing; Wang, Yuyi; Wang, Zhe; Wang, Zheng; Wang, Zhimin; Watcharangkool, Apimook; Wei, Wei; Wei, Wei; Wei, Wenlu; Wei, Yadong; Wei, Yuehuan; Wen, Liangjian; Weng, Jun; Wiebusch, Christopher; Wirth, Rosmarie; Wu, Chengxin; Wu, Diru; Wu, Qun; Wu, Yinhui; Wu, Yiyang; Wu, Zhi; Wurm, Michael; Wurtz, Jacques; Wysotzki, Christian; Xi, Yufei; Xia, Dongmei; Xian, Shishen; Xiang, Ziqian; Xiao, Fei; Xiao, Xiang; Xie, Xiaochuan; Xie, Yijun; Xie, Yuguang; Xin, Zhao; Xing, Zhizhong; Xu, Benda; Xu, Cheng; Xu, Donglian; Xu, Fanrong; Xu, Hangkun; Xu, Jiayang; Xu, Jilei; Xu, Jing; Xu, Jinghuan; Xu, Meihang; Xu, Xunjie; Xu, Yin; Xu, Yu; Yan, Baojun; Yan, Qiyu; Yan, Taylor; Yan, Xiongbo; Yan, Yupeng; Yang, Changgen; Yang, Chengfeng; Yang, Fengfan; Yang, Jie; Yang, Lei; Yang, Pengfei; Yang, Xiaoyu; Yang, Yifan; Yang, Yixiang; Yang, Zekun; Yao, Haifeng; Ye, Jiaxuan; Ye, Mei; Ye, Ziping; Yermia, Frédéric; You, Zhengyun; Yu, Boxiang; Yu, Chiye; Yu, Chunxu; Yu, Guojun; Yu, Hongzhao; Yu, Miao; Yu, Xianghui; Yu, Zeyuan; Yu, Zezhong; Yuan, Cenxi; Yuan, Chengzhuo; Yuan, Ying; Yuan, Zhenxiong; Yue, Baobiao; Zafar, Noman; Zamogilnyi, Kirill; Zavadskyi, Vitalii; Zeng, Fanrui; Zeng, Shan; Zeng, Tingxuan; Zeng, Yuda; Zhan, Liang; Zhang, Aiqiang; Zhang, Bin; Zhang, Binting; Zhang, Feiyang; Zhang, Hangchang; Zhang, Haosen; Zhang, Honghao; Zhang, Jialiang; Zhang, Jiawen; Zhang, Jie; Zhang, Jingbo; Zhang, Jinnan; Zhang, Junwei; Zhang, Lei; Zhang, Peng; Zhang, Ping; Zhang, Qingmin; Zhang, Shiqi; Zhang, Shu; Zhang, Shuihan; Zhang, Siyuan; Zhang, Tao; Zhang, Xiaomei; Zhang, Xin; Zhang, Xuantong; Zhang, Yibing; Zhang, Yinhong; Zhang, Yiyu; Zhang, Yongpeng; Zhang, Yu; Zhang, Yuanyuan; Zhang, Yumei; Zhang, Zhenyu; Zhang, Zhijian; Zhao, Jie; Zhao, Rong; Zhao, Runze; Zhao, Shujun; Zhao, Tianhao; Zheng, Hua; Zheng, Yangheng; Zhou, Jing; Zhou, Li; Zhou, Nan; Zhou, Shun; Zhou, Tong; Zhou, Xiang; Zhou, Xing; Zhu, Jingsen; Zhu, Kangfu; Zhu, Kejun; Zhu, Zhihang; Zhuang, Bo; Zhuang, Honglin; Zong, Liang; Zou, Jiaheng; JUNO Collaboration
    We explore the decay of bound neutrons in the JUNO liquid scintillator detector into invisible particles (e.g., n → 3 ν or n n → 2 ν ), which do not produce an observable signal. The invisible decay includes two decay modes: n → inv and n n → inv . The invisible decays of s-shell neutrons in 12 C will leave a highly excited residual nucleus. Subsequently, some de-excitation modes of the excited residual nuclei can produce a time- and space-correlated triple coincidence signal in the JUNO detector. Based on a full Monte Carlo simulation informed with the latest available data, we estimate all backgrounds, including inverse beta decay events of the reactor antineutrino ν ¯ e , natural radioactivity, cosmogenic isotopes and neutral current interactions of atmospheric neutrinos. Pulse shape discrimination and multivariate analysis techniques are employed to further suppress backgrounds. With two years of exposure, JUNO is expected to give an order of magnitude improvement compared to the current best limits. After 10 years of data taking, the JUNO expected sensitivities at a 90% confidence level are τ / B ( n → inv ) > 5.0 × 10 31 years and τ / B ( n n → inv ) > 1.4 × 10 32 years .
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    Reactive Oxygen Species Potentiate the P2X(2) Receptor Activity through Intracellular Cys(430)
    (SOC NEUROSCIENCE, 2009) Coddou, Claudio; Codocedo, Juan F.; Li, Shuo; Lillo, Juan G.; Acuna Castillo, Claudio; Bull, Paulina; Stojilkovic, Stanko S.; Huidobro Toro, J. Pablo
    P2X receptor channels (P2XRs) are allosterically modulated by several compounds, mainly acting at the ectodomain of the receptor. Like copper, mercury, a metal that induces oxidative stress in cells, also stimulates the activity of P2X(2)R and inhibits the activity of P2X(4)R. However, the mercury modulation is not related to the extracellular residues critical for copper modulation. To identify the site(s) for mercury action, we generated two chimeras using the full size P2X(2) subunit, termed P2X(2a), and a splice variant lacking a 69 residue segment in the C terminal, termed P2X(2b), as the donors for intracellular and transmembrane segments and the P2X(4) subunit as the donor for ectodomain segment of chimeras. The potentiating effect of mercury on ATP-induced current was preserved in Xenopus oocytes expressing P2X(4/2a) chimera but was absent in oocytes expressing P2X(4/2b) chimera. Site-directed mutagenesis experiments revealed that the Cys(430) residue mediates effects of mercury on the P2X(2a)R activity. Because mercury could act as an oxidative stress inducer, we also tested whether hydrogen peroxide (H2O2) and mitochondrial stress inducers myxothiazol and rotenone mimicked mercury effects. These experiments, done in both oocytes and human embryonic kidney HEK293 cells, revealed that these compounds potentiated the ATP-evoked P2X(2a)R and P2X(4/2a)R currents but not P2X(2b)R and P2X(2a)-C430A and P2X(2a)-C430S mutant currents, whereas antioxidants dithiothreitrol and N-acetylcysteine prevented the H2O2 potentiation. Alkylation of Cys(430) residue with methylmethane-thiosulfonate also abolished the mercury and H2O2 potentiation. Altogether, these results are consistent with the hypothesis that the Cys(430) residue is an intracellular P2X(2a)R redox sensor.