Browsing by Author "Larsson, A."
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- ItemEffects on Pulmonary Vascular Mechanics of Two Different Lung-Protective Ventilation Strategies in an Experimental Model of Acute Respiratory Distress Syndrome(2017) Santos, A.; Gómez, E.; Monge, M.; Retamal Montes, Jaime; Borges, J.; Tusman, G.; Hedenstierna, G.; Larsson, A.; Suarez, F.
- ItemHigh PEEP levels are associated with overdistension and tidal recruitment/derecruitment in ARDS patients(2015) Retamal Montes, Jaime; Bugedo Tarraza, Guillermo; Larsson, A.; Bruhn, Alejandro
- ItemHigh respirat ory rate is associated with early reduction of lungedema clearance in an experimental model of ARDS(2016) Retamal Montes, Jaime; Borges, J.; Bruhn, Alejandro; Cao, X.; Feinstein, R.; Hedenstierna, G.; Johansson, S.; Suarez, F.; Larsson, A.
- ItemHigh respiratory rate favors pulmonary edema in an experimental model of acute lung injury(2014) Retamal Montes, Jaime; Borges, J. B.; Suarez-Sipmann, F.; Bruhn, Alejandro; Hedenstierna, G.; Larsson, A.
- ItemOpen lung approach ventilation abolishes the negative effects of respiratory rate in experimental lung injury(2016) Retamal Montes, Jaime; Borges, J.; Bruhn, Alejandro; Feinstein, R.; Hedenstierna, G.; Suarez, F.; Larsson, A.
- ItemPhysiological and inflammatory consequences of high and low respiratory rate in acute respiratory distress syndrome(John Wiley and Sons Inc, 2021) Retamal, J.; Damiani, L.F.; Basoalto, R.; Bruhn, A.; Bugedo, G.; Benites, M.H.; Larsson, A.© 2021 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons LtdUsing protective mechanical ventilation strategies with low tidal volume is usually accompanied by an increment of respiratory rate to maintain adequate alveolar ventilation. However, there is no robust data that support the safety of a high respiratory rate concerning ventilator-induced lung injury. Several experimental animal studies have explored the effects of respiratory rate over lung physiology, using a wide range of frequencies and different models. Clinical evidence is scarce and restricted to the physiological impact of increased respiratory rate. Undoubtedly, the respiratory rate can influence respiratory mechanics in various ways as a factor of multiplication of the power of ventilation, and gas exchange, and also on alveolar dynamics. In this narrative review, we present our point of view over the main experimental and clinical evidence available regarding the effect of respiratory rate on ventilator-induced lung injury development.