Browsing by Author "Ksiazek, TG"

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    An outbreak of hantavirus pulmonary syndrome, Chile, 1997
    (1998) Toro, J; Vega, JD; Khan, AS; Mills, JN; Padula, P; Terry, W; Yadón, Z; Valderrama, R; Ellis, BA; Pavletic, C; Cerda, R; Zaki, S; Wun-Ju, S; Meyer, R; Tapia, M; Mansilla, C; Baro, M; Vergara, JA; Concha, M; Calderon, G; Enria, D; Peters, CJ; Ksiazek, TG
    An outbreak of 25 cases of Andes virus-associated hantavirus pulmonary syndrome (HPS) was recognized in southern Chile from July 1997 through January 1998. In addition to the HPS patients, three persons with mild hantaviral disease and one person with asymptomatic acute infection were identified. Epidemiologic studies suggested person-to-person transmission in two of three family clusters. Ecologic studies showed very high densities of several species of sigmodontine rodents in the area.
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    Hantavirus pulmonary syndrome in a Chilean patient with recent travel in Bolivia
    (1998) Espinoza, R; Vial, P; Noriega, LM; Johnson, A; Nichol, ST; Rollin, PE; Wells, R; Zaki, S; Reynolds, E; Ksiazek, TG
    A case of hantavirus pulmonary syndrome (HPS) was serologically confirmed in a critically ill patient in Santiago, Chile. The patient's clinical course had many similarities to that of other HPS patients in North and South America but was complicated by acute severe renal failure. The patient's history included self-reported urban and probable rural rodent exposure during travel in Bolivia. Comparison of a viral sequence from an acute-phase serum sample with other known hantaviruses showed that the hantavirus nucleic acid sequence from the patient was very similar to a virus recently isolated from rodents associated with HPS cases in Paraguay.