Browsing by Author "Hidalgo Acuña, Leonel Esteban"

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    A methodology for developing dermatological datasets: lessons from retrospective data collection for AI-based applications
    (2025) Pedro Pérez, Alma Alheli; Romero Jofré, Pamela Ignacia; Vidaurre, Soledad; Cabanas, Ana M.; Galaz, Atsuko; Hidalgo Acuña, Leonel Esteban; Carrasco, Karina; Tamez-Peña, José Gerardo; Díaz-Domínguez, Ricardo; Navarrete Dechent, Cristian Patricio; Mery Quiroz, Domingo Arturo
    Purpose The integration of artificial intelligence into dermatological research has underscored the need for robust and well-structured dermatological datasets. However, these datasets vary widely in their development processes, and there is currently no standard methodology to create such datasets. This work identifies three pressing needs for the building of dermatological datasets focus on skin tumor classification: the need for multimodal datasets, the definition of minimum metadata requirements, and the inclusion of underrepresented populations to address the scarcity of health data. Methods We propose a practical methodology to create dermatological datasets from clinical records, incorporating both images and patient metadata. The process consists of four key stages: getting the institutional review board approval and analysis of clinical information sources, data recording and structuring, processing of clinical data and images, and quality assessment. This methodology was derived from hands-on experience in building two datasets from Chilean and Mexican populations, respectively. Results The methodology allows the creation of well-structured datasets by simplifying data organization and enabling replication. Each step includes practical guidance for dealing with typical challenges, such as image metadata categorization and technical validation by dermatologists and computer scientists. Conclusion Our contribution offers a reproducible, scalable, and interdisciplinary framework for creating dermatological datasets, especially useful for countries initiating dataset creation. In addition to the methodological proposal, we highlight common pitfalls and offer recommendations to mitigate them.
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    Creating a dermatologic database for artificial intelligence, a Chilean experience, and advice from ChatGPT
    (John Wiley and Sons Inc, 2024) Hidalgo Acuña, Leonel Esteban; Salinas, María Paz; Sepúlveda, Javiera; Carrasco, Karina; Romero, Pamela; Pedro, Alma; Vidaurre, Soledad; Mery, Domingo; Navarrete Dechent, Cristian
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    Management of periocular keratinocyte carcinomas with Mohs micrographic surgery and predictors of complex reconstruction: a retrospective study
    (2023) Peirano, Dominga; Vargas Mancilla, Sebastián Enrique; Hidalgo Acuña, Leonel Esteban; Donoso Mendieta, Francisca; Abusleme, Eugenia; Sanhueza Zamora, Felipe Alberto; Cárdenas de la Torre, Consuelo Paz; Droppelmann, Katherine; Castro Ayala, Juan Camilo; Uribe González, Pablo Francisco; Zoroquiain Velez, José Pablo; Navarrete Dechent, Cristián Patricio
    Background: Skin cancer is the most frequent cancer worldwide and the most frequent periocular tumor. Keratinocyte Carcinomas (KC) located in periorificial areas, such as periocular tumors, are considered high-risk tumors. Mohs Micrographic Surgery (MMS) is considered the first line for the treatment of high-risk KC, providing a lower recurrence rate than conventional wide excision. Objective: To describe the clinical-pathological features of periocular KC treated with MMS in a tertiary university center in Chile. Methods: A single-center, retrospective study of patients with KC located on the periocular area, that underwent MMS between 2017---2022. MMS details were recorded. Results: One hundred thirteen patients with periocular carcinomas were included. The mean age was 59 ± 13 years; 52% were women. The most frequent location was the medial canthus (53%), followed by the lower eyelid (30.1%). The most frequent BCC histology was the nodular variant (59.3%). Regarding MMS, the average number of stages was 1.5 ± 0.7, and 54% of the cases required only 1 stage to achieve clear margins. To date, no recurrence has been reported. Tumors larger than 8.5 mm in largest diameter or 43.5 mm2were more likely to require complex reconstruction. Study limitations: Retrospective design and a relatively low number of patients in the SCC group. Possible selection bias, as larger or more complex cases, may have been referred to oculoplastic surgeons directly.
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    Manejo de carcinomas queratinocíticos perioculares com cirurgia micrográfica de Mohs e preditores de reconstrução complexa: estudo retrospectivo
    (2024) Peirano, Dominga; Vargas, Sebastián; Hidalgo Acuña, Leonel Esteban; Donoso Mena, Francisca; Albuseme, Eugenia; Sanhueza Zamora, Felipe Alberto; Cardenas De La Torre, Consuelo Paz; Droppelmann Droppelmann, Katherine Ann; Castro, Juan Camilo; Uribe González, Pablo Francisco; Zoroquiain Vélez, José Pablo; Navarrete Dechent, Cristian Patricio
    Fundamentos: O câncer de pele é o tipo mais frequente em todo o mundo e o mais frequente tumor periocular. Os carcinomas queratinocíticos (CQ) localizados em áreas perioculares são considerados tumores de alto risco. A cirurgia micrográfica de Mohs (CMM) é considerada a primeira linha para o tratamento do CQ de alto risco, com menor taxa de recorrência do que a excisão ampla convencional. Objetivo: Descrever as características clinico-patológicas do CQ periocular tratado com CMM em um centro universitário terciário no Chile. Métodos: Estudo retrospectivo unicêntrico de pacientes com CQ localizado na região periocular, submetidos à CMM entre 2017 e 2022. Detalhes da CMM foram registrados. Resultados: Foram incluídos 113 pacientes com carcinomas perioculares. A média de idade foi de 59 ± 13 anos; 52% eram mulheres. A localização mais frequente foi o canto medial do olho (53%), seguido da pálpebra inferior (30,1%). O tipo histológico mais frequente de carcinoma basocelular (CBC) foi o nodular (59,3%). Em relação à CMM, o número médio de estágios foi de 1,5 ± 0,7, e 54% dos casos necessitaram de apenas um estágio para atingir margens livres. Até o momento, nenhuma recorrência foi relatada. Tumores maiores que 8,5 mm em seu maior diâmetro ou 43,5 mm² foram mais propensos a necessitar de reconstrução complexa.
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    The role of ultraviolet-induced fluorescence dermatoscopy for the detection of multiple aggregated yellow-white globules in basal cell carcinoma
    (American Academy of Dermatology, Inc., 2024) Navarrete Dechent, Cristian Patricio; Pietkiewicz, Pawel; Astronave, Gisel; Marghoob, Nadeem G.; Dusza, Stephen W.; Lorenzoni Gaete, María Josefina; Boleira, Manuela; Cristopher, Michael; Valdivia Agüero, Rosario del Pilar; Bustos, Sergio; Jaimes, Natalia; Kurpis, María; Hidalgo Acuña, Leonel Esteban; Abarzúa Araya, Alvaro Rodrigo; Zoroquiain Velez, José Pablo; Uribe González, Pablo Francisco; Cárdenas de la Torre, Consuelo Paz; Droppelmann Droppelmann Katherine Ann; Marghoob, Ashfaq A.
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    Ultraviolet induced fluorescent dermoscopy for the diagnosis of skin tumors: A multicenter study
    (2025) Navarrete Dechent, Cristian Patricio; Pietkiewicz, Pawel; Abarzua Araya, Alvaro Rodrigo; Valdivia Agüero, Rosario Del Pilar; Dusza, Stephen W.; Anriot, Julien; Garces Cea, Javiera; Villagran Essmann, Sofia Paz; Bustos Crisostomo, Sergio Eduardo; González Valdes, Sebastián Alejandro; Ibañez Ibañez, Samuel; Boleira, Manuela; Jaimes, Natalia; Swanson, David; Hidalgo Acuña, Leonel Esteban; Droppelmann Droppelmann, Katherine Ann; Cardenas De La Torre, Consuelo Paz; Uribe González, Pablo Francisco; Marghoob, Ashfaq A.
    Abstract:BackgroundUltraviolet-induced fluorescent dermoscopy (UVFD) is a novel dermoscopic technique that has shown potential to improve diagnostic accuracy for select conditions in small case series. However, its performance has not yet been assessed in a large cohort of cutaneous tumors.ObjectiveTo evaluate the role of UVFD in cutaneous tumors.MethodsThis retrospective, multicenter study included consecutive lesions assessed at three tertiary care clinics in Chile, France, and Poland. Standard polarized dermoscopic images and UVFD images were independently reviewed by two expert dermoscopists, with consensus evaluation. Established dermoscopic criteria, as well as border definition and the presence of “ochre color,” were specifically assessed.Results551 lesions were included. The most frequent diagnosis was basal cell carcinoma (28.2%) followed by melanocytic nevus (18.6%), and melanoma (12.8%). Keratin, comedo-like openings, and fissures and ridges were better seen under UVFD. The border definition of lesions was also better seen under UVFD. Ochre color was seen under UVFD mostly in invasive melanomas.LimitationsRetrospective study. Some tumors were underrepresented.ConclusionUVFD enhances specific keratin-related dermoscopic structures and colors. It also provides for better border delineation and may help in identifying invasive melanomas via the presence of ochre color.