Browsing by Author "Gonzalez, R"

Now showing 1 - 10 of 10
  • Thumbnail Image
    Item
    A short cervix in women with preterm labor and intact membranes: A risk factor for microbial invasion of the amniotic cavity
    (MOSBY-ELSEVIER, 2005) Gomez, R; Romero, R; Nien, JK; Chaiworapongsa, T; Medina, L; Kim, YM; Yoon, BH; Carstens, M; Espinoza, J; Iams, JD; Gonzalez, R
    Objective: The purpose of this study was to determine whether there was a relationship between sonographic cervical length and the presence of culture-proven microbial invasion of the ammotic cavity in women with preterm labor and intact membranes.
  • Thumbnail Image
    Item
    Comparison of isoflurane, halothane and fentanyl in patients with decreased ejection fraction undergoing coronary surgery
    (AUSTRALIAN SOC ANAESTHETISTS, 1996) Urzua, J; Serra, M; Lema, G; Canessa, R; Gonzalez, R; Meneses, G; Irarrazaval, M; Moran, S
    The aim of the study was to compare three anaesthetic agents in patients with ejection fraction below 0.40 subjected to coronary revascularization surgery. Twenty-five elective coronary surgical patients with ejection fraction below 0.40 were prospectively studied. Premedication was pethidine 1 mg/kg and induction was fentanyl 0.03 mg/kg and pancuronium 0.1 mg/kg. The patients were randomized to one of three maintenance techniques (fentanyl, isoflurane or halothane).
  • Thumbnail Image
    Item
    Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse Intestine
    (ELSEVIER SCIENCE BV, 1995) Chianale, J; Vollrath, V; Wielandt, AM; Miranda, S; Gonzalez, R; Fresno, AM; Quintana, C; Gonzalez, S; Andrade, L; Guzman, S
    P-glycoprotein is a multidrug transporter encoded by the mdr3 gene in the mouse intestinal epithelium. The aims of this study were to characterize the mdr3 gene expression in the cephalocaudal axis of the intestine in adult animals and during perinatal development, and to define the molecular mechanism responsible for the heterogeneous expression of the gene along the cephalocaudal axis. RNA extracted from stomach, duodenum, jejunum, ileum, cecum and colon was hybridized by slot blot and Northern blot using a mdr3 cDNA probe. The regulation of gene expression was investigated examining the rate of transcription by nuclear run-off analysis. Transport studies of rhodamine 123, a substrate of P-glycoprotein, were performed in everted jejunum and ileum. The level of mdr3 mRNA and P-glycoprotein found in ileum was 6-fold higher than the level found in duodenum. The regional pattern of mdr3 gene expression is established in the intestine of 10-day-old animals. Similar mdr3 hybridization signal in nuclear run-off assay was found in nuclei of enterocytes isolated from jejunum and ileum, suggesting that the heterogeneous expression of the mdr3 gene in the cephalocaudal axis of the small bowel may be predominantly regulated at the post-transcriptional level. Transport rate of rhodamine 123 from the serosal to mucosal side in everted ileum was higher than the rate of transport found in jejunum. These results indicate that enterocytes of the ileum may be more actively involved in the P-glycoprotein-mediated transport of xenobiotics into the intestinal lumen.
  • Thumbnail Image
    Item
    Effect of primary coronary angioplasty on left ventricular function and myocardial perfusion as determined by Tc-99m sestamibi scintigraphy
    (EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2001) Castro, PF; Corbalan, R; Baeza, R; Nazzal, C; Greig, DP; Miranda, FP; Gonzalez, R; Marchant, E; Olea, E; Larrain, G
    Twenty-foul consecutive patients undergoing primary angioplasty were systematically studied with technetium-99m sestamibi myocardial scanning before intervention at 72 hours and at 3 months. Treatment with primary angioplasty was associated with a significant early decrease in the perfusion defect size, followed by a later improvement in left ventricular dimensions and ejection fraction.
  • Thumbnail Image
    Item
    Effects of glucose-insulin-potassium solution on myocardial salvage and left ventricular function after primary angioplasty
    (LIPPINCOTT WILLIAMS & WILKINS, 2003) Castro, PF; Larrain, G; Baeza, R; Corbalan, R; Nazzal, C; Greig, DP; Miranda, FP; Perez, O; Acevedo, M; Marchant, E; Olea, E; Gonzalez, R
    Objective. To evaluate the effects of glucose-insulin-potassium (GIK) therapy on infarct size and left ventricular function when used as an adjuvant therapy to primary angioplasty.
  • Thumbnail Image
    Item
    Generalization of positive attitude as a function of subgroup and superordinate group identifications in intergroup contact
    (JOHN WILEY & SONS LTD, 2003) Gonzalez, R; Brown, R
    The role of category salience in mediating the effects of intergroup contact was examined. One theoretical model proposes that some psychological salience of subgroup categories is necessary to facilitate the generalization of attitude change beyond the immediate contact situation. Another argues that a re-categorization of the subgroups into a new superordinate category is more beneficial, whilst a third suggests that de-categorizing the situation entirely is optimal. An alternative view, which combines the first two models, proposes a Dual Identity strategy (simultaneous high superordinate and high subgroup categorization) as an important mediator of the relationship between contact variables and intergroup attitudes. In the study, participants (N = 114) undertook a cooperative intergroup task under four conditions of category salience: 'subgroup', 'superordinate', 'superordinate and subgroup', and,no group salience'. Evaluative ratings and symbolic reward allocations both for the groups encountered (contact) and those outside the situation (generalization) provided measures of intergroup bias. Bias within the contact situation was mainly eliminated in all conditions. However on the more generalized bias measures, only the 'superordinate' and 'superordinate and subgroup' (Dual Identity strategy) conditions maintained this low level; in the other two conditions intergroup bias resurfaced. A combination of the first two models is proposed. Copyright (C) 2002 John Wiley Sons, Ltd.
  • Thumbnail Image
    Item
    Idiopathic vaginal bleeding during pregnancy as the only clinical manifestation of intrauterine infection
    (TAYLOR & FRANCIS LTD, 2005) Gomez, R; Romero, R; Nien, JK; Medina, L; Carstens, M; Kim, YM; Chaiworapongsa, T; Espinoza, J; Gonzalez, R
    Objective. To determine the frequency and clinical significance of microbial invasion of the amniotic cavity (MIAC) in patients with vaginal bleeding in the absence of placenta previa, preterm labor or preterm premature rupture of membranes (PROM).
  • No Thumbnail Available
    Item
    Radiofrequency catheter ablation of slow-pathway conduction. Experience in 30 cases
    (SOC MEDICA SANTIAGO, 1995) Vergara, I; Acevedo, M; Fajuri, A; Cambon, AM; Rosas, A; Gonzalez, R
    Atrioventricular nodal reentry tachycardia (AVNRT) is one of the most frequent mechanism of paroxysmal supraventricular tachycardia. In these patient tachycardia is maintained due to anterograde conduction through a slow pathway and retrograde conduction to the atrium via a fast pathway. We present herein our experience in ablation of the slow pathway. Since January 1993, 30 consecutive patients with AVNRT underwent attempted catheter ablation of the slow pathway. Mean age was 35 +/- 3.7 years. All patients has symptomatic tachycardia and six had history of syncope. Electrophysiologic studies revealed AVNRT in all patients, in addition, two patients had a left accessory pathway. Slow pathway ablation was performed with a Mansfield 7 F catheter, guided by both fluoroscopic positioning and endocardial signals. A mean of 13 bursts were applied. in the 30 patients conduction through the slow pathway was interrupted, and thus tachycardia was no longer inducible. Retrograde conduction post ablation was evaluated in 17 of the 30 patients, significant changes were observed in three of them. One patient developed second degree AV block and a permanent observed in three of them. One patient developed second degree AV block and a permanent pacemaker was implanted. Another patient had recurrence of tachycardia three months post ablation. After a second attempt she is arrhythmia free. Patients have been followed for a mean of 15.7 +/- 2.5 months and are asymptomatic in the absence of antiarrhythmic therapy.
  • No Thumbnail Available
    Item
    Reduction in neonatal mortality in Chile between 1990 and 2000
    (2006) Gonzalez, R; Merialdi, M; Lincetto, O; Lauer, J; Becerra, C; Castro, R; García, P; Saugstad, OD; Villar, J
    OBJECTIVE. Our objective with this article was to describe the declining trend in neonatal mortality in Chile between 1990 and 2000 and examine potential causal factors.
  • Thumbnail Image
    Item
    Successful liver transplantation and delivery in a woman with fulminant hepatic failure occurring during the second trimester of pregnancy
    (WILEY, 2006) Jarufe, N; Soza, A; Perez Ayuso, RM; Poblete, JA; Gonzalez, R; Guajardo, M; Hernandez, V; Riquelme, A; Arrese, M; Martinez, J
    Background: Severe liver dysfunction occurring during pregnancy is an unusual but dramatic event that poses special technical and ethical issues because it involves two lives. Methods an Results: We report the case of a 35-year-old woman with cryptogenic fulminant hepatic failure who underwent successful orthotopic liver transplantation at 22 weeks of pregnancy. After a relatively uneventful post-operative course she delivered a normal offspring at the 27th week of gestation. There were no obstetrical complications and neonatal outcome was excellent. After a year of follow-up, the patient is doing well,and the newborn has exhibited normal psychomotor and weight/height development. Conclusions: This case illustrates the challenge of treating fulminant hepatic failure during pregnancy and demonstrates that liver transplantation is a feasible therapeutic option for treatment of patients with this condition, allowing successful completion of pregnancy.