Browsing by Author "Gonzalez, F."

Now showing 1 - 6 of 6
  • Thumbnail Image
    Item
    Characterization of the phone-calls made to a poison center related to household and cosmetics products exposition in pediatrics
    (SOC CHILENA PEDIATRIA, 2019) Gonzalez, F.; Retamal, C.; Silva, L.; Cerda, P.; Medel, P.; Solari, S.; Mellado, R.; Rios, J. C.
    Introduction: Household cleaning products and cosmetics are necessary for daily life and widely used by the population. However, their use may not be risk-free, especially when they are not used or stored as recommended. It is important to characterize exposures, as this is useful for developing strategies to reduce morbidity, mortality, and health costs associated, especially in the child population. Objective: To describe reports associated with household cleaning products and cosmetics exposure in patients under the age of 12, reported to the Poison Information Center of the Catholic University of Chile (CITUC). Patients and Method: Descriptive cross-sectional study of phone calls to CITUC during 2016. The analyzed variables were age, sex, product, caller, caller and incident location, exposure circumstances, exposure route(s), symptoms, and severity from manual records and from the WHO's electronic record software 'INTOX Data Management System'. Results: 3,415 cases met the inclusion criteria. Children under the age of five represented 91% of the exposures, and 58.5% were male. 99.4% were accidental exposures, and 98.6% occurred at home. Family members (57%) and health personnel (42%) made the calls. 68.3% of the patients had no symptoms after exposure. The four products with the highest incidence were household bleach (27.6%), floor cleaners and polishers (13.1%), dish soap (7.9%), and perfume/cologne (5.8%). The main exposure route was by ingestion (89.4%). Conclusions: Household cleaning products and cosmetics are common causes of exposures especially in children under the age of five. Although these products have a low morbidity and mortality rate, it is important to educate the population to prevent possible poisonings in the child population.
  • Thumbnail Image
    Item
    Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor
    (2020) Abrigo, J.; Gonzalez, F.; Aguirre, F.; Tacchi, F.; Gonzalez, A.; Meza, M. P.; Simon, F.; Cabrera García, Daniel Alejandro; Arrese, Marco; Karpen, S.; Cabello Verrugio, Claudio Alejandro
  • Thumbnail Image
    Item
    La Reforma Agraria Chilena: Hechos Estilizados a la Luz de una Nueva Base de Datos
    (2017) Cuesta J. I.; Díaz Bahamonde, José Gregorio; Gallego Yáñez, Francisco; Gonzalez, F.; Marshall Rivera, Guillermo
  • No Thumbnail Available
    Item
    The European Solar Telescope
    (2022) Noda, C. Quintero; Schlichenmaier, R.; Bellot Rubio, L. R.; Lofdahl, M. G.; Khomenko, E.; Leenaarts, J.; Kuckein, C.; Gonzalez Manrique, S. J.; Gunar, S.; Nelson, C. J.; Rodriguez, J. de la Cruz; Tziotziou, K.; Tsiropoula, G.; Aulanier, G.; Aboudarham, J.; Allegri, D.; Alsina Ballester, E.; Amans, J. P.; Asensio Ramos, A.; Bailen, F. J.; Balaguer, M.; Baldini, V; Balthasar, H.; Barata, T.; Barczynski, K.; Barreto Cabrera, M.; Baur, A.; Bechet, C.; Beck, C.; Belio-Asin, M.; Bello-Gonzalez, N.; Belluzzi, L.; Bentley, R. D.; Berdyugina, S., V; Berghmans, D.; Berlicki, A.; Berrilli, F.; Berkefeld, T.; Bettonvil, F.; Bianda, M.; Bienes Perez, J.; Bonaque-Gonzalez, S.; Brajsa, R.; Bommier, V; Bourdin, P-A; BurgosMartin, J.; Calchetti, D.; Calcines, A.; Calvo Tovar, J.; Campbell, R. J.; Carballo-Martin, Y.; Carbone, V; Carlin, E. S.; Carlsson, M.; Castro Lopez, J.; Cavaller, L.; Cavallini, F.; Cauzzi, G.; Cecconi, M.; Chulani, H. M.; Cirami, R.; Consolini, G.; Coretti, I; Cosentino, R.; Cozar-Castellano, J.; Dalmasse, K.; Danilovic, S.; Ovelar, M. De Juan; Del Moro, D.; del Pino Aleman, T.; del Toro Iniesta, J. C.; Denker, C.; Dhara, S. K.; Di Marcantonio, P.; Baso, C. J. Diaz; Diercke, A.; Dineva, E.; Diaz-Garcia, J. J.; Doerr, H-P; Doyle, G.; Erdelyi, R.; Ermolli, I; Escobar Rodriguez, A.; Esteban Pozuelo, S.; Faurobert, M.; Felipe, T.; Feller, A.; Feijoo Amoedo, N.; Femenia Castella, B.; Fernandes, J.; Ferro Rodriguez, I; Figueroa, I; Fletcher, L.; Franco Ordovas, A.; Gafeira, R.; Gardenghi, R.; Gelly, B.; Giorgi, F.; Gisler, D.; Giovannelli, L.; Gonzalez, F.; Gonzalez, J. B.; Gonzalez-Cava, J. M.; Gonzalez Garcia, M.; Gomory, P.; Gracia, F.; Grauf, B.; Greco, V; Grivel, C.; Guerreiro, N.; Guglielmino, S. L.; Hammerschlag, R.; Hanslmeier, A.; Hansteen, V; Heinzel, P.; Hernandez-Delgado, A.; Hernandez Suarez, E.; Hidalgo, S. L.; Hill, F.; Hizberger, J.; Hofmeister, S.; Jagers, A.; Janett, G.; Jarolim, R.; Jess, D.; Jimenez Mejias, D.; Jolissaint, L.; Kamlah, R.; Kapitan, J.; Kasparova, J.; Keller, C. U.; Kentischer, T.; Kiselman, D.; Kleint, L.; Klvana, M.; Kontogiannis, I; Krishnappa, N.; Labrosse, N.; Lagg, A.; Degl'Innocenti, E. Landi; Langlois, M.; Lafon, M.; Laforgue, D.; Le Men, C.; Lepori, B.; Lepreti, F.; Lindberg, B.; Lilje, P. B.; Ariste, A. Lopez; Lopez Fernandez, V. A.; Lopez Jimenez, A. C.; Lopez Lopez, R.; Sainz, R. Manso; Marassi, A.; Marco de la Rosa, J.; Marino, J.; Marrero, J.; Martin, A.; Martin Galvez, A.; Martin Hernando, Y.; Masciadri, E.; MartinezGonzalez, M.; Matta-Gomez, A.; Mato, A.; Mathioudakis, M.; Matthews, S.; Mein, P.; Merlos Garcia, F.; Moity, J.; Montilla, I; Molinaro, M.; Molodij, G.; Montoya, L. M.; Munari, M.; Murabito, M.; Nunez Cagigal, M.; Oliviero, M.; Orozco Suarez, D.; Ortiz, A.; Padilla-Hernandez, C.; Paez Mana, E.; Paletou, F.; Pancorbo, J.; Pastor Canedo, A.; Yabar, A. Pastor; Peat, A. W.; Pedichini, F.; Peixinho, N.; Penate, J.; Perez de Taoro, A.; Peter, H.; Petrovay, K.; Piazzesi, R.; Pietropaolo, E.; Pleier, O.; Poedts, S.; Potzi, W.; Podladchikova, T.; Prieto, G.; Quintero Nehrkorn, J.; Ramelli, R.; Ramos Sapena, Y.; Rasilla, J. L.; Reardon, K.; Rebolo, R.; Regalado Olivares, S.; Reyes Garcia-Talavera, M.; Riethmuller, T. L.; Rimmele, T.; Rodriguez Delgado, H.; Rodriguez Gonzalez, N.; Rodriguez-Losada, J. A.; Rodriguez Ramos, L. F.; Romano, P.; Roth, M.; vander Voort, L. Rouppe; Rudawy, P.; Ruiz de Galarreta, C.; Rybak, J.; Salvade, A.; Sanchez-Capuchino, J.; Sanchez Rodriguez, M. L.; Sangiorgi, M.; Sayede, F.; Scharmer, G.; Scheiffelen, T.; Schmidt, W.; Schmieder, B.; Scire, C.; Scuderi, S.; Siegel, B.; Sigwarth, M.; Simoes, P. J. A.; Snik, F.; Sliepen, G.; Sobotka, M.; Socas-Navarro, H.; Sola La Serna, P.; Solanki, S. K.; Soler Trujillo, M.; Soltau, D.; Sordini, A.; Sosa Mendez, A.; Stangalini, M.; Steiner, O.; Stenflo, J. O.; Stepan, J.; Strassmeier, K. G.; Sudar, D.; Suematsu, Y.; Sutterlin, P.; Tallon, M.; Temmer, M.; Tenegi, F.; Tritschler, A.; Trujillo Bueno, J.; Turchi, A.; Utz, D.; van Harten, G.; VanNoort, M.; van Werkhoven, T.; Vansintjan, R.; Vaz Cedillo, J. J.; Vega Reyes, N.; Verma, M.; Veronig, A. M.; Viavattene, G.; Vitas, N.; Vogler, A.; von der Luhe, O.; Volkmer, R.; Waldmann, T. A.; Walton, D.; Wisniewska, A.; Zeman, J.; Zeuner, F.; Zhang, L. Q.; Zuccarello, F.; Collados, M.
    The European Solar Telescope (EST) is a project aimed at studying the magnetic connectivity of the solar atmosphere, from the deep photosphere to the upper chromosphere. Its design combines the knowledge and expertise gathered by the European solar physics community during the construction and operation of state-of-the-art solar telescopes operating in visible and near-infrared wavelengths: the Swedish 1m Solar Telescope, the German Vacuum Tower Telescope and GREGOR, the French Telescope Heliographique pour l'etude du Magnetisme et des Instabilites Solaires, and the Dutch Open Telescope. With its 4.2 m primary mirror and an open configuration, EST will become the most powerful European ground-based facility to study the Sun in the coming decades in the visible and near-infrared bands. EST uses the most innovative technological advances: the first adaptive secondary mirror ever used in a solar telescope, a complex multi-conjugate adaptive optics with deformable mirrors that form part of the optical design in a natural way, a polarimetrically compensated telescope design that eliminates the complex temporal variation and wavelength dependence of the telescope Mueller matrix, and an instrument suite containing several (etalon-based) tunable imaging spectropolarimeters and several integral field unit spectropolarimeters. This publication summarises some fundamental science questions that can be addressed with the telescope, together with a complete description of its major subsystems.
  • Thumbnail Image
    Item
  • No Thumbnail Available
    Item
    Trans-ancestry genome wide association study of childhood body mass index identifies novel loci and age specific effects
    (2025) Downie, C.G.; Shrestha, P.; Okello, S.; Yaser, M.; Lee, H.H.; Wang, Y.; Krishnan, M.; Chen, H.-H.; Justice, A.E.; Chittoor, G.; Josyula, N.S.; Gahagan, S.; Blanco, E.; Burrows, R.; Correa-Burrows, P.; Albala, C.; Santos Martin, José Luis; Angel, B.; Lozoff, B.; Hartwig, F. P.; Horta, B.; Brina, K. R.; Isasi, C.R.; Qi, Q.; Gallo, L. C.; Perreira, K. M.; Thyagarajan, B.; Daviglus, M.; Van Horn, L.; Gonzalez, F.; Bradfield, J.P.; Hakonarson, H.; Grant, S.F.A.; Below, J.E.; Felix, J.; Graff, M.; Divaris, K.; North, K.E.
    Over the past 30 years, obesity prevalence has markedly increased globally, including among children. Although genome-wide association studies (GWASs) have identified over 1,000 genetic loci associated with obesity-related traits in adults, the genetic architecture of childhoodobesity is less well characterized. Moreover, most childhood obesity GWASs havebeenrestrictedto severelyobese children,in relatively small sample sizes, and in primarily European-ancestry populations. To identify genetic loci associated with early-childhood body mass index (BMI), we performed GWAS of BMI Z scores in eight ancestrally diverse cohorts: ZOE 2.0 cohort, the Santiago Longitudinal Study (SLS), the Vanderbilt University BioVU biobank, the Geisinger MyCode Health Initiative biobank, Study of Latino (SOL) Youth, Pelotas (Brazil) Birth Cohort, Cameron County Hispanic Cohort (CCHC), and Viva La Familia cohort. We subsequently performed inverse-variance-weighted fixed-effect meta-analysis of these results with previously published GWAS summary statistics of BMIZscores of children in the Early GrowthGenetics (EGG) Consortium and the Norwegian Mother andChild Cohort (MoBa), constituting a final total of 84,804 individuals. We identified 39 genome-wide significant loci associated with childhood BMI, including three putatively novel loci (EFNA5 and DTWD2, RP11-2N5.1 on chromosome 5, and LSM14A on chromosome 19). We also observed a dynamic nature of genetic loci-BMI associations across the life course, with distinct effects across childhood and adulthood, highlighting possible critical periods for early-childhood interventions. These findings strengthen calls for larger population-based studies of children across age strata and across diverse populations.