Browsing by Author "García, D."

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Relevance of adjusted cut-off values in commercial serological immunoassays for Helicobacter pylori infection in children
    (2005) Harris, Paul R.; Perez-Perez, G.; Zylberberg, A.; Rollán, A.; Serrano, C.; Riera, F.; Einisman, H.; García, D.; Viviani, P.
    We assessed the sensitivity and specificity of H. pylori IgG and IgA with a commercial immunoassay performed in Chile and a second non-commercial immunoassay performed in a reference laboratory in the United States, in serum of 80 children and adults referred for gastrointestinal endoscopies in a developing country. Overall, 56% of the patients were infected with H. pylori based on rapid urease test and staining techniques on gastric biopsies. When Receiver Operator Curves (ROC) were developed, the sensitivity and specificity were similar for IgG and IgA. Both immunoassays exhibited better specificity, positive and negative predictive value (NPV) in children than in adults when cut-off values were corrected according to the local population than when they were assessed using the cut-off values pre-defined in other populations. These results underline the need to establish more precise cut-off values corrected in the local populations where assessments of antibodies as diagnostic markers of H. pylori infection are planning. © 2005 Springer Science+Business Media, Inc.
  • Thumbnail Image
    Item
    The Khorana score for prediction of venous thromboembolism in cancer patients : An individual patient data meta-analysis
    (2020) Van Es, N.; Ventresca, M.; Di Nisio, M.; Zhou, Q.; Noble, S.; Crowther, M.; Briel, M.; García, D.; Lyman, G. H.; Neumann Burotto, Gonzalo Ignacio; Macbeth, F.; Griffiths, G.; Iorio, A.; Mbuagbaw, L.; Brozek, J.; Guyatt, G.; Streiff, M. B.; Baldeh, T.; Florez, I. D.; Alma, O. G.; Agnelli, G.; Ageno, W.; Marcucci, M.; Bozas, G.; Zulian, G.; Maraveyas, A.; Lebeau, B.; Lecumberri, R.; Sideras, K.; Loprinzi, C.; McBane, R.; Pelzer, U.; Riess, H.; Solh, Z.; Perry, J.; Kahale, L. A.; Bossuyt, P. M.; Klerk, C.; Buller, H. R.; Akl, E. A.; Schunemann, H. J.
  • Thumbnail Image
    Item
    Use of heparins in patients with cancer : individual participant data meta-analysis of randomised trials study protocol
    (2016) Schunemann, H.; Ventresca, M.; Crowther, M.; Briel, M.; Zhou, Q.; García, D.; Lyman, G.; Iorio, A.; Beyene, J.; Neumann Burotto, Gonzalo Ignacio; Van Es, N.; Brozek, J.; Guyatt, G.; Levine, M.; Santesso, N.; Baldeh, T.