Browsing by Author "Florin, Carla"

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    Four-month-old with severe PIK3CA-related overgrowth spectrum disorder successfully treated with alpelisb
    (2024) Cossio, Maria-Laura; Rodriguez, Josefina; Flores, Juan Carlos; De Barbieri, Florencia; Flores, Alvaro; Marin, Jose; Florin, Carla; Cuevas, Francisco; Gutierrez, Monserrat
    PIK3CA-related overgrowth spectrum (PROS) encompasses different clinical entities caused by somatic activating mutations in PIK3CA. Among PROS, CLOVES syndrome represents a severe phenotype with poor survival rate. We present the case of a 4-month-old girl with CLOVES syndrome successfully treated with alpelisib, a PIKC3A inhibitor.
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    Retroauricular Island Flap as an Innovation for Microtia Ear Reconstruction
    (LIPPINCOTT WILLIAMS & WILKINS, 2010) Gloria Morovic, Carmen; Searle, Susana; Vidal, Claudia; Florin, Carla
    The use of a local island flap, designed with retroauricular skin, is an excellent, simple, and reproducible innovation to the classic microtia ear reconstruction, allowing adequate coverage of the cartilage framework, specifically of the conchal area, sparing tense skin closure, reducing skin suffering and necrosis, with a better aesthetic result achieving the naturally depressed concha aspect. The flap design and surgical technique is described. This flap was used in 13 consecutive microtia ear reconstructions in our unit, no complications were encountered, and aesthetic results were excellent.
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    Salival Fistulae: A Rare Complication After Microtic Ear Reconstruction
    (LIPPINCOTT WILLIAMS & WILKINS, 2011) Gloria Morovic, Carmen; Florin, Carla; Searle, Susana; Vidal, Claudia
    Parotid fistulae are a very infrequent complication after ear reconstruction in microtia when the local conditions are favorable. We report 2 cases of salival fistulae after microtic ear reconstruction. Timing of the diagnosis is important to decide the treatment. We recommend conservative management by restricted citric diet in early postoperative salival fistulae and Botox injections in the case that it persists.